Professor | 资治科 | 数字化转型顾问

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Name

资治科

Contact Information

zk.zi@siat.ac.cn

Language ability

中文, 德语, 英语

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2005-08--2008-10 博士: 德国洪堡大学 2002-09--2005-07 硕士: 清华大学 1998-09--2002-06 学士: 中南民族大学
Work Experience	2022-07~现在 - 中国科学院深圳先进技术研究院 - 研究员 2019-01~2022-06 - 德国联邦风险评估研究所 - 终身科学研究员 2014-05~2018-12 - 德国马克斯普朗克分子遗传所 - 研究员、课题组长 (Group Leader, PI) 2009-11~2014-04 - 德国弗莱堡大学 - 项目组长 2009-01~2009-10 - 德国洪堡大学 - 博士后

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Areas of Focus	系统生物学生物信息学
Publications	Liebig’s law of the minimum in the TGF-β/SMAD pathway, 通讯作者, 2024 Machine learning unveils RNA polymerase II binding as a predictor for SMAD2‐dependent transcription dynamics in response to Actvin signalling, 通讯作者, 2024 PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes, 第6作者, 2023 Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications, 第3作者, 2020 Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest, 通讯作者, 2020 Molecular Engineering of the TGF-β Signaling Pathway, 通讯作者, 2019 eDetect: A Fast Error Detection and Correction Tool for Live Cell Imaging Data Analysis, 通讯作者, 2019 Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21, 通讯作者, 2019 Spatiotemporal Control of TGF- β Signaling with Light, 通讯作者, 2018 Quantitative analysis of transient and sustained transforming growth factor‐β signaling dynamics, 通讯作者, 2011 SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models, 通讯作者, 2011 Time-Dependent Quantitative Multicomponent Control of the G(1)-S Network by the Stress-Activated Protein Kinase Hog1 upon Osmostress, 第2作者, 2011

Areas of Focus

系统生物学
生物信息学

Publications

Liebig’s law of the minimum in the TGF-β/SMAD pathway, 通讯作者, 2024
Machine learning unveils RNA polymerase II binding as a predictor for SMAD2‐dependent transcription dynamics in response to Actvin signalling, 通讯作者, 2024
PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes, 第6作者, 2023
Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications, 第3作者, 2020
Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest, 通讯作者, 2020
Molecular Engineering of the TGF-β Signaling Pathway, 通讯作者, 2019
eDetect: A Fast Error Detection and Correction Tool for Live Cell Imaging Data Analysis, 通讯作者, 2019
Tissue-Specific Chk1 Activation Determines Apoptosis by Regulating the Balance of p53 and p21, 通讯作者, 2019
Spatiotemporal Control of TGF- β Signaling with Light, 通讯作者, 2018
Quantitative analysis of transient and sustained transforming growth factor‐β signaling dynamics, 通讯作者, 2011
SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models, 通讯作者, 2011
Time-Dependent Quantitative Multicomponent Control of the G(1)-S Network by the Stress-Activated Protein Kinase Hog1 upon Osmostress, 第2作者, 2011

系统生物学: 计算生物学建模模拟网络分析路径分析动态系统生物系统定量生物学系统理论综合生物学生物信息学: 数据分析基因组学蛋白质组学序列比对机器学习计算工具生物数据库算法开发转录组学结构生物学

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