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Chengyu Zou
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English, German
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Neurodegenerative Diseases Cell Death Inflammation Ripk1 Als Alzheimer'S Disease Microglia Endothelial Cell Death Ischemic Brain Injury Necroptosis
Areas of Focus
  • Neurodegenerative Diseases
  • Cell Death and Inflammation
Work Experience
  • 2016-03~2021-01 - Harvard Medical School - Postdoctoral Researcher
  • 2011-09~2015-11 - Ludwig Maximilian University of Munich - PhD
  • 2008-09~2011-06 - Chongqing University - Master's
  • 2004-09~2008-06 - Southwest University - Bachelor's
Academic Background & Achievements
  • 2011-09--2015-11 PhD: Ludwig Maximilian University of Munich
  • 2008-09--2011-06 Master's: Chongqing University
  • 2004-09--2008-06 Bachelor's: Southwest University
Publications
  • Elevated peripheral levels of receptor-interacting protein kinase 1 (RIPK1) and IL-8 as biomarkers of human amyotrophic lateral sclerosis, 8th Author, 2023
  • Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury, 2nd Author, 2023
  • Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO), 8th Author, 2022
  • Microglial Dysfunction in Neurodegenerative Diseases via RIPK1 and ROS, 11th Author, 2022
  • Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, 3rd Author, 2022
  • Genetic Regulation of RIPK1 and Necroptosis, 2nd Author, 2021
  • A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis, 11th Author, 2021
  • Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer’s Disease, 1st Author, 2020
  • NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation, 1st Author, 2020
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