Professor | Jiacheng Bi | Asia Growth Partners

Name	Jiacheng Bi
Contact Information	jc.bi@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

Name

Jiacheng Bi

Contact Information

jc.bi@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2008-09--2014-06 PhD: University of Science and Technology of China 2004-09--2008-06 Bachelor's: South China University of Technology
Work Experience	2018-12~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher 2016-08~2018-12 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Assistant Researcher 2014-09~2016-08 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Postdoctoral Researcher
Awards	Chinese Society for Immunology Young Scholar Award (2018): Special Prize, National Level Chinese Academy of Sciences President's Excellence Award (2014): First Prize, Institute Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2008-09--2014-06 PhD: University of Science and Technology of China
2004-09--2008-06 Bachelor's: South China University of Technology

Work Experience

2018-12~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
2016-08~2018-12 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Assistant Researcher
2014-09~2016-08 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Postdoctoral Researcher

Awards

Chinese Society for Immunology Young Scholar Award (2018): Special Prize, National Level
Chinese Academy of Sciences President's Excellence Award (2014): First Prize, Institute Level

Areas of Focus	Basic Immunology of NK Cells Tumor Immunology
Publications	Checkpoint TIPE2 Limits the Helper Functions of NK Cells in Supporting Antitumor CD8(+) T Cells, Jiacheng Bi, 2023 TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells, Jiacheng Bi, 2023 Synthetic immunology and future NK cell immunotherapy, Jiacheng Bi, 2022 CD226: a potent driver of antitumor immunity that needs to be maintained, Jiacheng Bi, 2021 Exogenous oxidative stress suppresses IL-33 -driven proliferation programming in group 2 innate lymphoid cells, Jiacheng Bi, 2021 Increased expression of adenosine A3 receptor in tumor-infiltrating natural killer cells, Jiacheng Bi, 2021 Increased expression of adenosine A3 receptor in tumor-infiltrating NK cells, Jiacheng Bi, 2021 A natural product, Piperlongumine (PL), increases tumor cells sensitivity to NK cell killing, Jiacheng Bi, 2021 TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity, Jiacheng Bi, 2021 Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis, Jiacheng Bi, 2020 Molecular Regulation of NK Cell Maturation, Jiacheng Bi, 2020 IL-33-induced reactive oxygen species are required for optimal metabolic programming in group 2 innate lymphoid cells, Jiacheng Bi, 2020 Polyglutamine protein in tumor cells sensitizes tumor cells to natural killer cell cytolysis, Jiacheng Bi, 2020 NK Cell Dysfunction and Checkpoint Immunotherapy, Jiacheng Bi, 2019 Genetic reprogramming for NK cell cancer immunotherapy with CRISPR/Cas9, Jiacheng Bi, 2019 NK cell exhaustion and NK-based checkpoint blockade immunotherapy, Jiacheng Bi, 2019 Blockade of the checkpoint receptor tigit prevents nk cell exhaustion and elicits potent anti-tumor immunity, Jiacheng Bi, 2018 Impaired cytolytic activity of asthma-associated natural killer cells is linked to dysregulated transcriptional program in energy metabolism, Jiacheng Bi, 2018 JSI-124 inhibits IgE production in an IgE B cell line., Jiacheng Bi, 2017 Silencing c-Rel in macrophages dampens Th1 and Th17 immune responses and alleviates experimental autoimmune encephalomyelitis in mice, Jiacheng Bi, 2017 NK Cells Alleviate Lung Inflammation by Negatively Regulating Group 2 Innate Lymphoid Cells., Jiacheng Bi, 2017 NK Cell exhaustion., Jiacheng Bi, 2017 Cloning, expression of human IgE-Fc and generation of mouse anti-human IgE monoclonal antibody, Jiacheng Bi, 2016 T-Cell Ig and ITIM Domain Regulates Natural Killer Cell Activation in Murine Acute Viral Hepatitis, Jiacheng Bi, 2014 TIGIT Safeguards Liver Regeneration Through Regulating Natural Killer Cell-Hepatocyte Crosstalk, Jiacheng Bi, 2014

Areas of Focus

Basic Immunology of NK Cells
Tumor Immunology

Publications

Checkpoint TIPE2 Limits the Helper Functions of NK Cells in Supporting Antitumor CD8(+) T Cells, Jiacheng Bi, 2023
TIPE2 deletion improves the therapeutic potential of adoptively transferred NK cells, Jiacheng Bi, 2023
Synthetic immunology and future NK cell immunotherapy, Jiacheng Bi, 2022
CD226: a potent driver of antitumor immunity that needs to be maintained, Jiacheng Bi, 2021
Exogenous oxidative stress suppresses IL-33 -driven proliferation programming in group 2 innate lymphoid cells, Jiacheng Bi, 2021
Increased expression of adenosine A3 receptor in tumor-infiltrating natural killer cells, Jiacheng Bi, 2021
Increased expression of adenosine A3 receptor in tumor-infiltrating NK cells, Jiacheng Bi, 2021
A natural product, Piperlongumine (PL), increases tumor cells sensitivity to NK cell killing, Jiacheng Bi, 2021
TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity, Jiacheng Bi, 2021
Artemisinin sensitizes tumor cells to NK cell-mediated cytolysis, Jiacheng Bi, 2020
Molecular Regulation of NK Cell Maturation, Jiacheng Bi, 2020
IL-33-induced reactive oxygen species are required for optimal metabolic programming in group 2 innate lymphoid cells, Jiacheng Bi, 2020
Polyglutamine protein in tumor cells sensitizes tumor cells to natural killer cell cytolysis, Jiacheng Bi, 2020
NK Cell Dysfunction and Checkpoint Immunotherapy, Jiacheng Bi, 2019
Genetic reprogramming for NK cell cancer immunotherapy with CRISPR/Cas9, Jiacheng Bi, 2019
NK cell exhaustion and NK-based checkpoint blockade immunotherapy, Jiacheng Bi, 2019
Blockade of the checkpoint receptor tigit prevents nk cell exhaustion and elicits potent anti-tumor immunity, Jiacheng Bi, 2018
Impaired cytolytic activity of asthma-associated natural killer cells is linked to dysregulated transcriptional program in energy metabolism, Jiacheng Bi, 2018
JSI-124 inhibits IgE production in an IgE B cell line., Jiacheng Bi, 2017
Silencing c-Rel in macrophages dampens Th1 and Th17 immune responses and alleviates experimental autoimmune encephalomyelitis in mice, Jiacheng Bi, 2017
NK Cells Alleviate Lung Inflammation by Negatively Regulating Group 2 Innate Lymphoid Cells., Jiacheng Bi, 2017
NK Cell exhaustion., Jiacheng Bi, 2017
Cloning, expression of human IgE-Fc and generation of mouse anti-human IgE monoclonal antibody, Jiacheng Bi, 2016
T-Cell Ig and ITIM Domain Regulates Natural Killer Cell Activation in Murine Acute Viral Hepatitis, Jiacheng Bi, 2014
TIGIT Safeguards Liver Regeneration Through Regulating Natural Killer Cell-Hepatocyte Crosstalk, Jiacheng Bi, 2014

Nk Cells Immunology Tumor Cancer Therapy Immune Response Cell Biology Molecular Biology Cytotoxicity Immunotherapy

Yuliang Feng - Southern University of Science and Technology

Jialing Liu - Southern University of Science and Technology

Jun Tian - Southern University of Science and Technology

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