Professor | Changheng Tan | Asia Growth Partners

Name	Changheng Tan
Contact Information	chtan@simm.ac.cn
Language ability	Chinese, English
Province	Shanghai

Name

Changheng Tan

Contact Information

chtan@simm.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1996-08--2001-07 PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences 1989-09--1993-07 Bachelor: Nanchang University
Work Experience	2009-09~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher 2005-09~2009-09 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher 2001-07~2005-08 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher 1993-07~1996-08 - Nanchang University - Teaching Assistant

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1996-08--2001-07 PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1989-09--1993-07 Bachelor: Nanchang University

Work Experience

2009-09~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
2005-09~2009-09 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
2001-07~2005-08 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher
1993-07~1996-08 - Nanchang University - Teaching Assistant

Areas of Focus	Basic research in pharmacy and innovative drug development, including active substance research of traditional Chinese medicine, folk medicine, and other natural products, as well as structural optimization of natural active ingredients.
Publications	Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson., Wang, AiZhu, Han, Hua, Fang, QiangQiang, Tan, ChangHeng, 2023 Identification of a class of potent USP25/28 inhibitors with broad spectrum of anti-tumor activity., Jin Peng, Kun Jiang, Xiao Sun, Lingzhi Wu, Jiewei Wang, Xiaomei Xi, Xu Tan, Tingbo Liang, Changheng Tan, Pumin Zhang, 2022 Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson., Wang, AiZhu, Fang, QiangQiang, Feng, TongTong, Wei, RenJie, Jiang, Kun, Lu, Qun, Tan, ChangHeng, 2021 Structurally diverse polyprenylated acylphloroglucinols from Hypericum uralum Buch.-Ham. ex D. Don., Fang, QiangQiang, Feng, TongTong, Wang, AiZhu, He, WanYing, Wei, RenJie, Lu, Qun, Tan, ChangHeng, 2021 Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides., Wang, XiaoFeng, Zhu, Zhengdan, Hao, TingTing, Fang, QiangQiang, Jiang, Kun, Qu, ShiJin, Zuo, JiangPin, Zhu, Weiliang, He, ShiJun, Tan, ChangHeng, 2020 Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-beta clearance., Pan, RuiYuan, Ma, Jun, Kong, XiangXi, Wang, XiaoFeng, Li, ShuoShuo, Qi, XiaoLong, Yan, YuHan, Cheng, Jinbo, Liu, Qingsong, Jin, Wanzhu, Tan, ChangHeng, Yuan, Zengqiang, 2019 Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia., Wang, WanPing, Jiang, Kun, Zhang, Ping, Shen, KaiKai, Qu, ShiJin, Yu, XiaoPing, Tan, ChangHeng, 2018 Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein., Liu, Zulong, Zhu, Hengrui, Qu, Shijin, Tang, Lisha, Cao, Lihuan, Yu, Wenbo, Yang, Xianmei, Jiang, Songmin, Zhu, Dayuan, Tan, Changheng, Yu, Long, 2018 Deep eutectic solvents used as extraction solvent for the determination of flavonoids from Camellia oleifera flowers by high-performance liquid chromatography., Ma, Yaqian, Liu, Menghan, Tan, Ting, Yan, Aiping, Guo, Lan, Jiang, Kun, Tan, Changheng, Wan, Yiqun, 2018 Structurally diverse stilbene dimers from Gnetum montanum Markgr.: studies on the H-1 chemical shift differences between dimeric stilbene epimers correlating to the relative configurations., Zhai, YiMing, Jiang, Kun, Qu, ShiJin, Luo, HongFeng, Tan, JunJie, Tan, ChangHeng, 2016

Areas of Focus

Basic research in pharmacy and innovative drug development, including active substance research of traditional Chinese medicine, folk medicine, and other natural products, as well as structural optimization of natural active ingredients.

Publications

Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson., Wang, AiZhu, Han, Hua, Fang, QiangQiang, Tan, ChangHeng, 2023
Identification of a class of potent USP25/28 inhibitors with broad spectrum of anti-tumor activity., Jin Peng, Kun Jiang, Xiao Sun, Lingzhi Wu, Jiewei Wang, Xiaomei Xi, Xu Tan, Tingbo Liang, Changheng Tan, Pumin Zhang, 2022
Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson., Wang, AiZhu, Fang, QiangQiang, Feng, TongTong, Wei, RenJie, Jiang, Kun, Lu, Qun, Tan, ChangHeng, 2021
Structurally diverse polyprenylated acylphloroglucinols from Hypericum uralum Buch.-Ham. ex D. Don., Fang, QiangQiang, Feng, TongTong, Wang, AiZhu, He, WanYing, Wei, RenJie, Lu, Qun, Tan, ChangHeng, 2021
Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides., Wang, XiaoFeng, Zhu, Zhengdan, Hao, TingTing, Fang, QiangQiang, Jiang, Kun, Qu, ShiJin, Zuo, JiangPin, Zhu, Weiliang, He, ShiJun, Tan, ChangHeng, 2020
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-beta clearance., Pan, RuiYuan, Ma, Jun, Kong, XiangXi, Wang, XiaoFeng, Li, ShuoShuo, Qi, XiaoLong, Yan, YuHan, Cheng, Jinbo, Liu, Qingsong, Jin, Wanzhu, Tan, ChangHeng, Yuan, Zengqiang, 2019
Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia., Wang, WanPing, Jiang, Kun, Zhang, Ping, Shen, KaiKai, Qu, ShiJin, Yu, XiaoPing, Tan, ChangHeng, 2018
Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein., Liu, Zulong, Zhu, Hengrui, Qu, Shijin, Tang, Lisha, Cao, Lihuan, Yu, Wenbo, Yang, Xianmei, Jiang, Songmin, Zhu, Dayuan, Tan, Changheng, Yu, Long, 2018
Deep eutectic solvents used as extraction solvent for the determination of flavonoids from Camellia oleifera flowers by high-performance liquid chromatography., Ma, Yaqian, Liu, Menghan, Tan, Ting, Yan, Aiping, Guo, Lan, Jiang, Kun, Tan, Changheng, Wan, Yiqun, 2018
Structurally diverse stilbene dimers from Gnetum montanum Markgr.: studies on the H-1 chemical shift differences between dimeric stilbene epimers correlating to the relative configurations., Zhai, YiMing, Jiang, Kun, Qu, ShiJin, Luo, HongFeng, Tan, JunJie, Tan, ChangHeng, 2016

Pharmacy Innovative Drug Development Traditional Chinese Medicine Folk Medicine Natural Products Active Substance Research Structural Optimization Natural Active Ingredients Drug Discovery Pharmacology

Kui Hong - Wuhan University

Lian Duan - Wuhan University

Bingzheng Shen - Wuhan University

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