Professor | 谭昌恒 | 数字化转型顾问

Name	谭昌恒
Contact Information	chtan@simm.ac.cn
Language ability	中文, 英语
Province	上海

Name

谭昌恒

Contact Information

chtan@simm.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	1996-08--2001-07 博士: 中国科学院上海药物研究所 1989-09--1993-07 学士: 南昌大学
Work Experience	2009-09~现在 - 中国科学院上海药物研究所 - 研究员 2005-09~2009-09 - 中国科学院上海药物研究所 - 副研究员 2001-07~2005-08 - 中国科学院上海药物研究所 - 助理研究员 1993-07~1996-08 - 南昌大学 - 助教

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

1996-08--2001-07 博士: 中国科学院上海药物研究所
1989-09--1993-07 学士: 南昌大学

Work Experience

2009-09~现在 - 中国科学院上海药物研究所 - 研究员
2005-09~2009-09 - 中国科学院上海药物研究所 - 副研究员
2001-07~2005-08 - 中国科学院上海药物研究所 - 助理研究员
1993-07~1996-08 - 南昌大学 - 助教

Areas of Focus	从事药学基础研究和创新药物研发，主要包括中草药、民间药和其他天然产物的活性物质基础研究，以及天然活性成分的结构优化研究。
Publications	Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson., Wang, AiZhu, Han, Hua, Fang, QiangQiang, Tan, ChangHeng, 2023 Identification of a class of potent USP25/28 inhibitors with broad spectrum of anti-tumor activity., Jin Peng, Kun Jiang, Xiao Sun, Lingzhi Wu, Jiewei Wang, Xiaomei Xi, Xu Tan, Tingbo Liang, Changheng Tan, Pumin Zhang, 2022 Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson., Wang, AiZhu, Fang, QiangQiang, Feng, TongTong, Wei, RenJie, Jiang, Kun, Lu, Qun, Tan, ChangHeng, 2021 Structurally diverse polyprenylated acylphloroglucinols from Hypericum uralum Buch.-Ham. ex D. Don., Fang, QiangQiang, Feng, TongTong, Wang, AiZhu, He, WanYing, Wei, RenJie, Lu, Qun, Tan, ChangHeng, 2021 Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides., Wang, XiaoFeng, Zhu, Zhengdan, Hao, TingTing, Fang, QiangQiang, Jiang, Kun, Qu, ShiJin, Zuo, JiangPin, Zhu, Weiliang, He, ShiJun, Tan, ChangHeng, 2020 Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-beta clearance., Pan, RuiYuan, Ma, Jun, Kong, XiangXi, Wang, XiaoFeng, Li, ShuoShuo, Qi, XiaoLong, Yan, YuHan, Cheng, Jinbo, Liu, Qingsong, Jin, Wanzhu, Tan, ChangHeng, Yuan, Zengqiang, 2019 Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia., Wang, WanPing, Jiang, Kun, Zhang, Ping, Shen, KaiKai, Qu, ShiJin, Yu, XiaoPing, Tan, ChangHeng, 2018 Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein., Liu, Zulong, Zhu, Hengrui, Qu, Shijin, Tang, Lisha, Cao, Lihuan, Yu, Wenbo, Yang, Xianmei, Jiang, Songmin, Zhu, Dayuan, Tan, Changheng, Yu, Long, 2018 Deep eutectic solvents used as extraction solvent for the determination of flavonoids from Camellia oleifera flowers by high-performance liquid chromatography., Ma, Yaqian, Liu, Menghan, Tan, Ting, Yan, Aiping, Guo, Lan, Jiang, Kun, Tan, Changheng, Wan, Yiqun, 2018 Structurally diverse stilbene dimers from Gnetum montanum Markgr.: studies on the H-1 chemical shift differences between dimeric stilbene epimers correlating to the relative configurations., Zhai, YiMing, Jiang, Kun, Qu, ShiJin, Luo, HongFeng, Tan, JunJie, Tan, ChangHeng, 2016

Areas of Focus

从事药学基础研究和创新药物研发，主要包括中草药、民间药和其他天然产物的活性物质基础研究，以及天然活性成分的结构优化研究。

Publications

Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson., Wang, AiZhu, Han, Hua, Fang, QiangQiang, Tan, ChangHeng, 2023
Identification of a class of potent USP25/28 inhibitors with broad spectrum of anti-tumor activity., Jin Peng, Kun Jiang, Xiao Sun, Lingzhi Wu, Jiewei Wang, Xiaomei Xi, Xu Tan, Tingbo Liang, Changheng Tan, Pumin Zhang, 2022
Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson., Wang, AiZhu, Fang, QiangQiang, Feng, TongTong, Wei, RenJie, Jiang, Kun, Lu, Qun, Tan, ChangHeng, 2021
Structurally diverse polyprenylated acylphloroglucinols from Hypericum uralum Buch.-Ham. ex D. Don., Fang, QiangQiang, Feng, TongTong, Wang, AiZhu, He, WanYing, Wei, RenJie, Lu, Qun, Tan, ChangHeng, 2021
Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides., Wang, XiaoFeng, Zhu, Zhengdan, Hao, TingTing, Fang, QiangQiang, Jiang, Kun, Qu, ShiJin, Zuo, JiangPin, Zhu, Weiliang, He, ShiJun, Tan, ChangHeng, 2020
Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-beta clearance., Pan, RuiYuan, Ma, Jun, Kong, XiangXi, Wang, XiaoFeng, Li, ShuoShuo, Qi, XiaoLong, Yan, YuHan, Cheng, Jinbo, Liu, Qingsong, Jin, Wanzhu, Tan, ChangHeng, Yuan, Zengqiang, 2019
Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia., Wang, WanPing, Jiang, Kun, Zhang, Ping, Shen, KaiKai, Qu, ShiJin, Yu, XiaoPing, Tan, ChangHeng, 2018
Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein., Liu, Zulong, Zhu, Hengrui, Qu, Shijin, Tang, Lisha, Cao, Lihuan, Yu, Wenbo, Yang, Xianmei, Jiang, Songmin, Zhu, Dayuan, Tan, Changheng, Yu, Long, 2018
Deep eutectic solvents used as extraction solvent for the determination of flavonoids from Camellia oleifera flowers by high-performance liquid chromatography., Ma, Yaqian, Liu, Menghan, Tan, Ting, Yan, Aiping, Guo, Lan, Jiang, Kun, Tan, Changheng, Wan, Yiqun, 2018
Structurally diverse stilbene dimers from Gnetum montanum Markgr.: studies on the H-1 chemical shift differences between dimeric stilbene epimers correlating to the relative configurations., Zhai, YiMing, Jiang, Kun, Qu, ShiJin, Luo, HongFeng, Tan, JunJie, Tan, ChangHeng, 2016

药学创新药物研发中草药民间药天然产物活性物质研究结构优化天然活性成分药物发现药理学

虞沂 - 武汉大学

周宇波 - 中国科学院大学

洪葵 - 武汉大学

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