Areas of Focus
- 从事药学基础研究和创新药物研发,主要包括中草药、民间药和其他天然产物的活性物质基础研究,以及天然活性成分的结构优化研究。
Work Experience
- 2009-09~现在 - 中国科学院上海药物研究所 - 研究员
- 2005-09~2009-09 - 中国科学院上海药物研究所 - 副研究员
- 2001-07~2005-08 - 中国科学院上海药物研究所 - 助理研究员
- 1993-07~1996-08 - 南昌大学 - 助教
Academic Background & Achievements
- 1996-08--2001-07 博士: 中国科学院上海药物研究所
- 1989-09--1993-07 学士: 南昌大学
Publications
- Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson., Wang, AiZhu, Han, Hua, Fang, QiangQiang, Tan, ChangHeng, 2023
- Identification of a class of potent USP25/28 inhibitors with broad spectrum of anti-tumor activity., Jin Peng, Kun Jiang, Xiao Sun, Lingzhi Wu, Jiewei Wang, Xiaomei Xi, Xu Tan, Tingbo Liang, Changheng Tan, Pumin Zhang, 2022
- Acmoxanthones A-E, New Lavandulated Xanthones from Hypericum acmosepalum N. Robson., Wang, AiZhu, Fang, QiangQiang, Feng, TongTong, Wei, RenJie, Jiang, Kun, Lu, Qun, Tan, ChangHeng, 2021
- Structurally diverse polyprenylated acylphloroglucinols from Hypericum uralum Buch.-Ham. ex D. Don., Fang, QiangQiang, Feng, TongTong, Wang, AiZhu, He, WanYing, Wei, RenJie, Lu, Qun, Tan, ChangHeng, 2021
- Alopecines A-E, five chloro-containing matrine-type alkaloids with immunosuppressive activities from the seeds of Sophora alopecuroides., Wang, XiaoFeng, Zhu, Zhengdan, Hao, TingTing, Fang, QiangQiang, Jiang, Kun, Qu, ShiJin, Zuo, JiangPin, Zhu, Weiliang, He, ShiJun, Tan, ChangHeng, 2020
- Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-beta clearance., Pan, RuiYuan, Ma, Jun, Kong, XiangXi, Wang, XiaoFeng, Li, ShuoShuo, Qi, XiaoLong, Yan, YuHan, Cheng, Jinbo, Liu, Qingsong, Jin, Wanzhu, Tan, ChangHeng, Yuan, Zengqiang, 2019
- Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia., Wang, WanPing, Jiang, Kun, Zhang, Ping, Shen, KaiKai, Qu, ShiJin, Yu, XiaoPing, Tan, ChangHeng, 2018
- Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein., Liu, Zulong, Zhu, Hengrui, Qu, Shijin, Tang, Lisha, Cao, Lihuan, Yu, Wenbo, Yang, Xianmei, Jiang, Songmin, Zhu, Dayuan, Tan, Changheng, Yu, Long, 2018
- Deep eutectic solvents used as extraction solvent for the determination of flavonoids from Camellia oleifera flowers by high-performance liquid chromatography., Ma, Yaqian, Liu, Menghan, Tan, Ting, Yan, Aiping, Guo, Lan, Jiang, Kun, Tan, Changheng, Wan, Yiqun, 2018
- Structurally diverse stilbene dimers from Gnetum montanum Markgr.: studies on the H-1 chemical shift differences between dimeric stilbene epimers correlating to the relative configurations., Zhai, YiMing, Jiang, Kun, Qu, ShiJin, Luo, HongFeng, Tan, JunJie, Tan, ChangHeng, 2016