Areas of Focus
- Systematic exploration, mechanism analysis, and artificial regulation of key RNA splicing abnormalities in cancer
- Molecular mechanism research of circular RNA processing and development of new circular RNA drugs
Work Experience
- 2016-03~Present - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Associate Researcher
- 2014-09~2015-09 - University of North Carolina at Chapel Hill - Visiting Scholar
- 2007-07~2016-03 - Fudan University - Young Faculty Member
Academic Background & Achievements
- 2002-09--2007-07 Ph.D.: South China Botanical Garden, Chinese Academy of Sciences
- 1998-09--2002-07 Bachelor's: Sichuan University
Publications
- RNA therapeutics: new vaccination and beyond, Wei, Huan-Huan, Liang-Liang Zheng, Wang, Zefeng, 2023
- A flexible, efficient, and scalable platform to produce circular RNAs as new therapeutics, 杨赟, 魏欢欢, 陈楚赟, 张恺, 韦彤, 汤辰翔, 李泽阳, 王泽峰, 2022
- Extensive Dysregulation of SLK Splicing in Cancers Impacts Metastasis, 杨英群, 胡玥, 张思蕊, 李杰夫, 姚睿捷, 张文静, 孙玉, 孙靖, 杨赟, 王泽峰, 魏欢欢, 2022
- A systematic survey of PRMT interactomes reveals the key roles of arginine methylation in the global control of RNA splicing and translation, Wei, HuanHuan, Fan, XiaoJuan, Hu, Yue, Tian, XiaoXu, Guo, Meng, Mao, MiaoWei, Fang, ZhaoYuan, Wu, Ping, Gao, ShuaiXin, Peng, Chao, Yang, Yun, Wang, Zefeng, 2021
- RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H, Zhang, Sirui, Bao, Yufang, Shen, Xianfeng, Pan, Yunjian, Sun, Yue, Xiao, Man, Chen, Kexuan, Wei, Huanhuan, Zuo, Ji, Saffen, David, Zong, WeiXing, Sun, Yihua, Wang, Zefeng, Wang, Yongbo, 2020
- Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning, Mao, Miaowei, Hu, Yue, Yang, Yun, Qian, Yajie, Wei, Huanhuan, Fan, Wei, Yang, Yi, Li, Xiaoling, Wang, Zefeng, 2018
- Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells, Wei, HuanHuan, Liu, Yuanlong, Wang, Yang, Lu, Qianyun, Yang, Xuerong, Li, Jiefu, Wang, Zefeng, 2017
- Conformational Features of ACE-Inhibitory Valine-Isoleucine-Proline Tripeptide in Aqueous Medium According to Molecular Dynamic Simulations and 2D-NMR Spectroscopy, Qi, Chunyan, Chen, Lin, Wei, Huanhuan, Zhang, Rong, Huang, Guodong, Wu, Wenjuan, 2016
- A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation, Yangfan Qi, Jing Yu, Wei Han, Xiaojuan Fan, Haili Qian, Huanhuan Wei, Yihsuan S Tsai, Jinyao Zhao, Wenjing Zhang, Quentin Liu, Songshu Meng, Yang Wang, Zefeng Wang, 2016
- Engineering RNA-binding proteins with diverse activities, Wei, Huanhuan, Wang, Zefeng, 2015
- U0126 inhibits pancreatic cancer progression via the KRAS signaling pathway in a zebrafish xenotransplantation model, Guo, Meng, Wei, Huanhuan, Hu, Jingying, Sun, Shaoyang, Long, Jiang, Wang, Xu, 2015
- DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation, Sun, Ruixin, Wu, Yi, Wang, Yuxiong, Zang, Kun, Wei, Huanhuan, Wang, Fangnian, Yu, Min, 2015
- Paecilomycins J–M, four new β-resorcylic acid lactones from Paecilomyces sp. SC0924, Liang-Xiong Xu, Ping Wu, Huan-Huan Wei, Jing-Hua Xue, Xiao-Peng Hu, Xiao-Yi Wei, 2013
- Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following Fc epsilon RI Aggregation, Fang, Xiaoyun, Lang, Yongjiang, Wang, Yuxiong, Mo, Wei, Wei, Huanhuan, Xie, Jianhui, Yu, Min, 2012
- Monocillin II Inhibits Human Breast Cancer Growth Partially by Inhibiting MAPK Pathways and CDK2 Thr160 Phosphorylation, Wei, Huanhuan, Xu, Liangxiong, Yu, Min, Zhang, Ling, Wang, Huijie, Wei, Xiaoyi, Ruan, Yuanyuan, 2012
- Sesquiterpenes and Lignans from Tephrosia vogelii, Wei, HuanHuan, Xu, HanHong, Xie, HaiHui, Xu, LiangXiang, Wei, XiaoYi, 2009
- Chemical constituents of the seeds of Ammopiptanthus (Leguminosae) and their systematic and ecological significance, Wei, Huanhuan, Wu, Ping, Ge, Xuejun, Liu, Meifang, Wei, Xiaoyi, 2007
Awards
- Second Prize, First National Systems Biology Conference (2019)
