Professor | 魏言欢 | 数字化转型顾问

Name	魏言欢
Contact Information	weiyh@sinh.ac.cn
Language ability	中文, 英语
Province	上海

Name

魏言欢

Contact Information

weiyh@sinh.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2002-09--2007-07 博士: 中国科学院华南植物研究所 1998-09--2002-07 学士: 四川大学
Work Experience	2016-03~现在 - 中国科学院上海营养与健康研究所 - 副研究员 2014-09~2015-09 - 北卡罗莱纳大学教堂山分校 - 青年骨干访问学者 2007-07~2016-03 - 复旦大学 - 青年骨干教师
Awards	第一届全国系统生物学大会二等奖 (2019)

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2002-09--2007-07 博士: 中国科学院华南植物研究所
1998-09--2002-07 学士: 四川大学

Work Experience

2016-03~现在 - 中国科学院上海营养与健康研究所 - 副研究员
2014-09~2015-09 - 北卡罗莱纳大学教堂山分校 - 青年骨干访问学者
2007-07~2016-03 - 复旦大学 - 青年骨干教师

Awards

第一届全国系统生物学大会二等奖 (2019)

Areas of Focus	癌症中关键RNA剪接异常的系统挖掘、机制解析和人工调控环形RNA加工的分子机理研究和新型环形RNA药物系统研发
Publications	RNA therapeutics: new vaccination and beyond, 魏欢欢, 梁亮亮, 王泽峰, 2023 A flexible, efficient, and scalable platform to produce circular RNAs as new therapeutics, 杨赟, 魏欢欢, 陈楚赟, 张恺, 韦彤, 汤辰翔, 李泽阳, 王泽峰, 2022 Extensive Dysregulation of SLK Splicing in Cancers Impacts Metastasis, 杨英群, 胡玥, 张思蕊, 李杰夫, 姚睿捷, 张文静, 孙玉, 孙靖, 杨赟, 王泽峰, 魏欢欢, 2022 A systematic survey of PRMT interactomes reveals the key roles of arginine methylation in the global control of RNA splicing and translation, 魏欢欢, 范晓娟, 胡玥, 田晓旭, 郭萌, 毛苗伟, 方兆元, 吴平, 高帅鑫, 彭超, 杨赟, 王泽峰, 2021 RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H, 张思睿, 鲍玉芳, 沈先峰, 潘云健, 孙玉, 肖曼, 陈克轩, 魏欢欢, 左继, 大卫·萨芬, 宗伟星, 孙义华, 王泽峰, 王永波, 2020 Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning, 毛苗伟, 胡玥, 杨赟, 钱雅洁, 魏欢欢, 范伟, 杨毅, 李晓玲, 王泽峰, 2018 Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells, 魏欢欢, 刘元龙, 王阳, 陆倩云, 杨雪蓉, 李杰夫, 王泽峰, 2017 Conformational Features of ACE-Inhibitory Valine-Isoleucine-Proline Tripeptide in Aqueous Medium According to Molecular Dynamic Simulations and 2D-NMR Spectroscopy, 齐春艳, 陈琳, 魏欢欢, 张荣, 黄国栋, 吴文娟, 2016 A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation, 杨帆, 余静, 韩伟, 范晓娟, 钱海丽, 魏欢欢, 蔡宜轩, 赵金耀, 张文静, 刘权, 孟松树, 王阳, 王泽峰, 2016 Engineering RNA-binding proteins with diverse activities, 魏欢欢, 王泽峰, 2015 U0126 inhibits pancreatic cancer progression via the KRAS signaling pathway in a zebrafish xenotransplantation model, 郭萌, 魏欢欢, 胡静莹, 孙少阳, 龙江, 王旭, 2015 DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation, 孙瑞新, 吴怡, 王玉雄, 臧坤, 魏欢欢, 王芳年, 余敏, 2015 Paecilomycins J–M, four new β-resorcylic acid lactones from Paecilomyces sp. SC0924, 徐良雄, 吴平, 魏欢欢, 薛静华, 胡小鹏, 魏小艺, 2013 Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following Fc epsilon RI Aggregation, 方晓云, 郎永江, 王玉雄, 莫伟, 魏欢欢, 谢建辉, 余敏, 2012 Monocillin II Inhibits Human Breast Cancer Growth Partially by Inhibiting MAPK Pathways and CDK2 Thr160 Phosphorylation, 魏欢欢, 徐良雄, 余敏, 张玲, 王慧杰, 魏小艺, 阮媛媛, 2012 Sesquiterpenes and Lignans from Tephrosia vogelii, 魏欢欢, 徐汉宏, 谢海辉, 徐良翔, 魏小艺, 2009 Chemical constituents of the seeds of Ammopiptanthus (Leguminosae) and their systematic and ecological significance, 魏欢欢, 吴平, 葛学军, 刘美芳, 魏小艺, 2007

Areas of Focus

癌症中关键RNA剪接异常的系统挖掘、机制解析和人工调控
环形RNA加工的分子机理研究和新型环形RNA药物系统研发

Publications

RNA therapeutics: new vaccination and beyond, 魏欢欢, 梁亮亮, 王泽峰, 2023
A flexible, efficient, and scalable platform to produce circular RNAs as new therapeutics, 杨赟, 魏欢欢, 陈楚赟, 张恺, 韦彤, 汤辰翔, 李泽阳, 王泽峰, 2022
Extensive Dysregulation of SLK Splicing in Cancers Impacts Metastasis, 杨英群, 胡玥, 张思蕊, 李杰夫, 姚睿捷, 张文静, 孙玉, 孙靖, 杨赟, 王泽峰, 魏欢欢, 2022
A systematic survey of PRMT interactomes reveals the key roles of arginine methylation in the global control of RNA splicing and translation, 魏欢欢, 范晓娟, 胡玥, 田晓旭, 郭萌, 毛苗伟, 方兆元, 吴平, 高帅鑫, 彭超, 杨赟, 王泽峰, 2021
RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H, 张思睿, 鲍玉芳, 沈先峰, 潘云健, 孙玉, 肖曼, 陈克轩, 魏欢欢, 左继, 大卫·萨芬, 宗伟星, 孙义华, 王泽峰, 王永波, 2020
Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning, 毛苗伟, 胡玥, 杨赟, 钱雅洁, 魏欢欢, 范伟, 杨毅, 李晓玲, 王泽峰, 2018
Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells, 魏欢欢, 刘元龙, 王阳, 陆倩云, 杨雪蓉, 李杰夫, 王泽峰, 2017
Conformational Features of ACE-Inhibitory Valine-Isoleucine-Proline Tripeptide in Aqueous Medium According to Molecular Dynamic Simulations and 2D-NMR Spectroscopy, 齐春艳, 陈琳, 魏欢欢, 张荣, 黄国栋, 吴文娟, 2016
A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation, 杨帆, 余静, 韩伟, 范晓娟, 钱海丽, 魏欢欢, 蔡宜轩, 赵金耀, 张文静, 刘权, 孟松树, 王阳, 王泽峰, 2016
Engineering RNA-binding proteins with diverse activities, 魏欢欢, 王泽峰, 2015
U0126 inhibits pancreatic cancer progression via the KRAS signaling pathway in a zebrafish xenotransplantation model, 郭萌, 魏欢欢, 胡静莹, 孙少阳, 龙江, 王旭, 2015
DNA methylation regulates bromodomain-containing protein 2 expression during adipocyte differentiation, 孙瑞新, 吴怡, 王玉雄, 臧坤, 魏欢欢, 王芳年, 余敏, 2015
Paecilomycins J–M, four new β-resorcylic acid lactones from Paecilomyces sp. SC0924, 徐良雄, 吴平, 魏欢欢, 薛静华, 胡小鹏, 魏小艺, 2013
Shp2 Activates Fyn and Ras to Regulate RBL-2H3 Mast Cell Activation following Fc epsilon RI Aggregation, 方晓云, 郎永江, 王玉雄, 莫伟, 魏欢欢, 谢建辉, 余敏, 2012
Monocillin II Inhibits Human Breast Cancer Growth Partially by Inhibiting MAPK Pathways and CDK2 Thr160 Phosphorylation, 魏欢欢, 徐良雄, 余敏, 张玲, 王慧杰, 魏小艺, 阮媛媛, 2012
Sesquiterpenes and Lignans from Tephrosia vogelii, 魏欢欢, 徐汉宏, 谢海辉, 徐良翔, 魏小艺, 2009
Chemical constituents of the seeds of Ammopiptanthus (Leguminosae) and their systematic and ecological significance, 魏欢欢, 吴平, 葛学军, 刘美芳, 魏小艺, 2007

Rna剪接癌症基因组 Tcga 分子机制 Rna调控天然产物甲基化精氨酸生物功能

王瑾 - 武汉大学

Area of Focus
肿瘤 | 免疫学 | 癌症 | 细胞反应 | 免疫系统 | 肿瘤学 | 研究 | 治疗 | 分子机制 | 临床应用

范成鹏 - 武汉大学

沈坤 - 武汉大学

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