Areas of Focus
- Targeted Antitumor Drugs
- Nucleoside Antiviral Drugs
- Total Synthesis of Antitumor Natural Products
Work Experience
- 2005-01 to Present - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Researcher
- 2002-01 to 2003-12 - Tsinghua Yuanxing Biopharmaceutical Technology - Chief Scientific Officer/Vice President
- 2002-01 to 2004-12 - Shanghai Jiao Tong University - Professor
- 1992-09 to 2001-12 - Gilead Sciences - Senior Scientist/Project Leader
- 1990-09 to 1992-08 - Duke University - Postdoctoral Researcher
Academic Background & Achievements
- 1985-09 to 1989-08 PhD: University of Pittsburgh
- 1984-09 to 1985-05 English Training: Sun Yat-sen University
- 1980-09 to 1984-07 Bachelor's: Fudan University
Publications
- Design, synthesis, and in vitro biological evaluation of novel 6-methyl-7-substituted-7-deaza purine nucleoside analogs as anti-influenza A agents, Jiancun Zhang, 2016
- Targeting tumor-associated immune suppression with selective protein kinase A type I (PKAI) inhibitors may enhance cancer immunotherapy, Jiancun Zhang, 2016
- Synthesis and Evaluation of 2'-Deoxy-2'-Spirodiflurocyclopropyl Nucleoside Analogs, Jiancun Zhang, 2016
- Dichotomous role of protein kinase A type I (PKAI) in the tumor microenvironment: A potential target for ‘two-in-one’ cancer chemoimmunotherapeutics, Jiancun Zhang, 2015
- Synthesis and biological evaluation of 3,5-disubstituted-4-alkynylisoxozales as a novel class of HSP90 inhibitors., Jiancun Zhang, 2015
- Syntheses of Indolizidine Alkaloids from Cascade Cross-Coupling of gem-Dibromoolefins, Jiancun Zhang, 2014
- Copper-Catalyzed Intramolecular Dehydrogenative Aminooxygenation: Direct Access to Formyl Substituted Aromatic N-Heterocycles, Jiancun Zhang, 2011
- A Practical Synthesis of 2-Aroylindoles from N-(2-Formylphenyl)trifluoroacetamides in PEG-400, Jiancun Zhang, 2011
- Practical one-pot protocol for the syntheses of 2-chloro-pyrrolo[3,2-d]pyrimidines, Jiancun Zhang, 2011
- A Direct Intramolecular C-H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles from N-Aryl-2-aminopyridines, Jiancun Zhang, 2010
- N,N -Di-Boc-Substituted Thiourea as a Novel and Mild Thioacylating Agent Applicable for the Synthesis of Thiocarbonyl Compounds, Jiancun Zhang, 2010
- Facile synthesis of 2-bromoindoles by ligandfree CuI-catalyzed intramolecular crosscoupling of gem- dibromoolefins, Jiancun Zhang, 2010
- A Formal Total Synthesis of Fostriecin by a Convergent Approach, Jiancun Zhang, 2010
- Dimerization of CPAP Orchestrates Centrosome Cohesion Plasticity, Jiancun Zhang, 2010
- Facile synthesis of benzoxazoles from 1,1-dibromoethenes, Jiancun Zhang, 2010
- Highly stereoselective synthesis of 20-deoxy-b-ribonucleosides via a 3’-(N-acetyl)-glycyl- directing group, Jiancun Zhang, 2010
