Professor | Naixia Zhang | Asia Growth Partners

Name	Naixia Zhang
Contact Information	nxzhang@mail.shcnc.ac.cn
Language ability	Chinese, English
Province	Shanghai

Name

Naixia Zhang

Contact Information

nxzhang@mail.shcnc.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1994.9 - 1998.7 Bachelor of Science in Medicinal Chemistry: Peking University Health Science Center 1998.9 - 2003.7 Ph.D. in Structural Biology: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 2004.5 - 2008.6 Postdoctoral Research: University of Minnesota
Work Experience	2010-10 - Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher 2008-05 - 2010-02 - University of Minnesota - Research Assistant Professor 2004-05 - 2008-05 - University of Minnesota - Postdoctoral Researcher 2003-08 - 2004-05 - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1994.9 - 1998.7 Bachelor of Science in Medicinal Chemistry: Peking University Health Science Center
1998.9 - 2003.7 Ph.D. in Structural Biology: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
2004.5 - 2008.6 Postdoctoral Research: University of Minnesota

Work Experience

2010-10 - Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
2008-05 - 2010-02 - University of Minnesota - Research Assistant Professor
2004-05 - 2008-05 - University of Minnesota - Postdoctoral Researcher
2003-08 - 2004-05 - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Researcher

Areas of Focus	NMR technology and computer molecular simulation technology to study interactions between proteins and between drug target proteins and small molecules; NMR metabolomics research related to diseases
Publications	Sodium Oligomannate Electrostatically Binds to Aβ and Blocks Its Aggregation, Zhou, Chen, Zhang, Jingjing, Luo, Xinwen, Lian, Fulin, Zeng, Yangyang, Zhang, Zhenqing, Zhang, Haiyan, Zhang, Naixia, 2023 Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines, Gao, Jing, Zhou, Chen, Zhong, Yan, Shi, Li, Luo, Xuanyang, Su, Haixia, Li, Minjun, Xu, Yechun, Zhang, Naixia, Zhou, Hu, 2023 Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment, Qing Wang, Sheng Yao, Ze-xian Yang, Chen Zhou, Yu Zhang, Ye Zhang, Lei Zhang, Jin-Tian Li, Zhi-Jian Xu, Wei-Liang Zhu, Nai-Xia Zhang, Yang Ye, Lin-Yin Feng, 2023 Structure-based discovery of potent USP28 inhibitors derived from Vismodegib, Di Zhou, Zhuo Xu, Yaodong Huang, Hui Wang, Xiaoli Zhu, Wentao Zhang, Weiwei Song, Tong Gao, Tongchao Liu, Meng Wang, Li Shi, Naixia Zhang, Bing Xiong, 2023 Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1, Zhu, Mengying, Wang, Hui, Ding, Yiluan, Yang, Yuanyuan, Xu, Zhuo, Shi, Li, Zhang, Naixia, 2022 High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases, Xiao, Senhao, Guo, Siqi, Han, Jie, Sun, Yanli, Wang, Mingchen, Chen, Yantao, Fang, Xueyu, Yang, Feng, Mu, Yajuan, Zhang, Liang, Ding, Yiluan, Zhang, Naixia, Jiang, Hualiang, Chen, Kaixian, Zhao, Kehao, Luo, Cheng, Chen, Shijie, 2022 Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis, Mao, Jianhua, Zhu, Kongkai, Long, Zhangbiao, Zhang, Huimin, Xiao, Bing, Xi, Wenda, Wang, Yun, Huang, Jiansong, Liu, Jingqiu, Shi, Xiaofeng, Jiang, Hao, Lu, Tian, Wen, Yi, Zhang, Naixia, Meng, Qian, Zhou, Hu, Ruan, Zheng, Wang, Jin, Luo, Cheng, Xi, Xiaodong, 2022 Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule, Lan, Xiaofang, Olaleye, Olajide E, Lu, Junlan, Yang, Wei, Du, Feifei, Yang, Junling, Cheng, Chen, Shi, Yanhong, Wang, Fengqing, Zeng, Xueshan, Tian, Nannan, Liao, Peiwei, Yu, Xuan, Xu, Fang, Li, Yingfei, Wang, Hongtao, Zhang, Naixia, Jia, Weiwei, Li, Chuan, 2021 5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma, Wang, Shuni, Yang, Hong, Su, Mingbo, Lian, Fulin, Cong, Zhanqing, Wei, Rongrui, Zhou, Yubo, Li, Xingjun, Zheng, Xingling, Li, Chunpu, Fu, Xuhong, Han, Xu, Shi, Qiongyu, Li, Cong, Zhang, Naixia, Geng, Meiyu, Liu, Hong, Li, Jia, Huang, Xun, Wang, Jiang, 2021 Protective Effects of 28-O-Cafeoyl Betulin (B-CA) on the Cerebral Cortex of Ischemic Rats Revealed by a NMR-Based Metabolomics Analysis (vol 89, pg 631, 2020), Liu, Xia, Ruan, Zhi, Shao, Xingcheng, Feng, Hongxuan, Wu, Lei, Wang, Wei, Wang, Hongmin, Mu, Hongyan, Zhang, Rujun, Zhao, Weimin, Zhang, Haiyan, Zhang, Naixia, 2021

Areas of Focus

NMR technology and computer molecular simulation technology to study interactions between proteins and between drug target proteins and small molecules; NMR metabolomics research related to diseases

Publications

Sodium Oligomannate Electrostatically Binds to Aβ and Blocks Its Aggregation, Zhou, Chen, Zhang, Jingjing, Luo, Xinwen, Lian, Fulin, Zeng, Yangyang, Zhang, Zhenqing, Zhang, Haiyan, Zhang, Naixia, 2023
Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines, Gao, Jing, Zhou, Chen, Zhong, Yan, Shi, Li, Luo, Xuanyang, Su, Haixia, Li, Minjun, Xu, Yechun, Zhang, Naixia, Zhou, Hu, 2023
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment, Qing Wang, Sheng Yao, Ze-xian Yang, Chen Zhou, Yu Zhang, Ye Zhang, Lei Zhang, Jin-Tian Li, Zhi-Jian Xu, Wei-Liang Zhu, Nai-Xia Zhang, Yang Ye, Lin-Yin Feng, 2023
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib, Di Zhou, Zhuo Xu, Yaodong Huang, Hui Wang, Xiaoli Zhu, Wentao Zhang, Weiwei Song, Tong Gao, Tongchao Liu, Meng Wang, Li Shi, Naixia Zhang, Bing Xiong, 2023
Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1, Zhu, Mengying, Wang, Hui, Ding, Yiluan, Yang, Yuanyuan, Xu, Zhuo, Shi, Li, Zhang, Naixia, 2022
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases, Xiao, Senhao, Guo, Siqi, Han, Jie, Sun, Yanli, Wang, Mingchen, Chen, Yantao, Fang, Xueyu, Yang, Feng, Mu, Yajuan, Zhang, Liang, Ding, Yiluan, Zhang, Naixia, Jiang, Hualiang, Chen, Kaixian, Zhao, Kehao, Luo, Cheng, Chen, Shijie, 2022
Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis, Mao, Jianhua, Zhu, Kongkai, Long, Zhangbiao, Zhang, Huimin, Xiao, Bing, Xi, Wenda, Wang, Yun, Huang, Jiansong, Liu, Jingqiu, Shi, Xiaofeng, Jiang, Hao, Lu, Tian, Wen, Yi, Zhang, Naixia, Meng, Qian, Zhou, Hu, Ruan, Zheng, Wang, Jin, Luo, Cheng, Xi, Xiaodong, 2022
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule, Lan, Xiaofang, Olaleye, Olajide E, Lu, Junlan, Yang, Wei, Du, Feifei, Yang, Junling, Cheng, Chen, Shi, Yanhong, Wang, Fengqing, Zeng, Xueshan, Tian, Nannan, Liao, Peiwei, Yu, Xuan, Xu, Fang, Li, Yingfei, Wang, Hongtao, Zhang, Naixia, Jia, Weiwei, Li, Chuan, 2021
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma, Wang, Shuni, Yang, Hong, Su, Mingbo, Lian, Fulin, Cong, Zhanqing, Wei, Rongrui, Zhou, Yubo, Li, Xingjun, Zheng, Xingling, Li, Chunpu, Fu, Xuhong, Han, Xu, Shi, Qiongyu, Li, Cong, Zhang, Naixia, Geng, Meiyu, Liu, Hong, Li, Jia, Huang, Xun, Wang, Jiang, 2021
Protective Effects of 28-O-Cafeoyl Betulin (B-CA) on the Cerebral Cortex of Ischemic Rats Revealed by a NMR-Based Metabolomics Analysis (vol 89, pg 631, 2020), Liu, Xia, Ruan, Zhi, Shao, Xingcheng, Feng, Hongxuan, Wu, Lei, Wang, Wei, Wang, Hongmin, Mu, Hongyan, Zhang, Rujun, Zhao, Weimin, Zhang, Haiyan, Zhang, Naixia, 2021

Nmr Molecular Simulation Protein Interactions Drug Targets Small Molecules Metabolomics Disease Research Structural Biology Biochemistry Computational Biology

Ning Jia - Southern University of Science and Technology

Ming-Yuan Su - Southern University of Science and Technology

Ji Yanxiao - Wuhan University

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