Professor | Weiliang Zhu | Asia Growth Partners

Name	Weiliang Zhu
Contact Information	wlzhu@simm.ac.cn
Language ability	Chinese, English
Province	Shanghai

Name

Weiliang Zhu

Contact Information

wlzhu@simm.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1995-09--1998-04 Ph.D.: Shanghai Institute of Materia Medica, Chinese Academy of Sciences 1986-09--1988-07 Master's Degree: Department of Chemistry, Soochow University 1979-09--1983-07 Bachelor's Degree: School of Chemistry and Chemical Engineering, Yangzhou University
Work Experience	2009-04~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Director of Drug Discovery and Design Center 2004-07~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher, Doctoral Supervisor 1998-05~2004-07 - Life Sciences and Technology Center, Singapore Polytechnic - Lecturer 1989-08~1995-08 - Agricultural College, Yangzhou University - Assistant Lecturer, Lecturer 1983-08~1986-08 - Agricultural College, Yangzhou University - Assistant Lecturer

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1995-09--1998-04 Ph.D.: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1986-09--1988-07 Master's Degree: Department of Chemistry, Soochow University
1979-09--1983-07 Bachelor's Degree: School of Chemistry and Chemical Engineering, Yangzhou University

Work Experience

2009-04~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Director of Drug Discovery and Design Center
2004-07~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher, Doctoral Supervisor
1998-05~2004-07 - Life Sciences and Technology Center, Singapore Polytechnic - Lecturer
1989-08~1995-08 - Agricultural College, Yangzhou University - Assistant Lecturer, Lecturer
1983-08~1986-08 - Agricultural College, Yangzhou University - Assistant Lecturer

Areas of Focus	Molecular Simulation and Drug Design Medicinal Chemistry
Publications	Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo, Sanfeng Dong, Ke Hu, Yulong Shi, Guanli Wang, Dandan Yu, Yitian Zhao, Hui Zhang, Yingcong Wang, Haiguo Sun, Zhijian Xu, Qi Jia, Yiming Li, Yingxia Li, Bo Li, Jumei Shi, Weiliang Zhu, 2024 Preferred microenvironments of halogen bonds and hydrogen bonds revealed using statistics and QM/MM calculation studies, Liping Zhou, Jintian Li, Yulong Shi, Leyun Wu, Weiliang Zhu, Zhijian Xu, 2023 Development of a Novel 18F-Labeled Probe for PET Imaging of Estrogen Receptor beta, Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Weiliang Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng, 2023 Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma, Li Xu, Yingcong Wang, Guanli Wang, Shushan Guo, Dandan Yu, Qilin Feng, Ke Hu, Gege Chen, Bo Li, Zhijian Xu, Xinyan Jia, Yumeng Lu, Hui Zhang, Xuejie Gao, Shuaikang Chang, Huaping Wang, Xiaosong Wu, Dongliang Song, Guang Yang, Huabin Zhu, Jinfeng Zhou, Fenghuang Zhan, Weiliang Zhu, Jumei Shi, 2023 红景天苷通过抑制TNF-α/NF-κB通路改善C2C12细胞萎缩的研究, 莉萍陈, 艳蕾张, 梦玲马, 湘萍康, 勇张, 志建徐, 维良朱, 张斌龚, 2023

Areas of Focus

Molecular Simulation and Drug Design
Medicinal Chemistry

Publications

Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo, Sanfeng Dong, Ke Hu, Yulong Shi, Guanli Wang, Dandan Yu, Yitian Zhao, Hui Zhang, Yingcong Wang, Haiguo Sun, Zhijian Xu, Qi Jia, Yiming Li, Yingxia Li, Bo Li, Jumei Shi, Weiliang Zhu, 2024
Preferred microenvironments of halogen bonds and hydrogen bonds revealed using statistics and QM/MM calculation studies, Liping Zhou, Jintian Li, Yulong Shi, Leyun Wu, Weiliang Zhu, Zhijian Xu, 2023
Development of a Novel 18F-Labeled Probe for PET Imaging of Estrogen Receptor beta, Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Weiliang Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng, 2023
Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma, Li Xu, Yingcong Wang, Guanli Wang, Shushan Guo, Dandan Yu, Qilin Feng, Ke Hu, Gege Chen, Bo Li, Zhijian Xu, Xinyan Jia, Yumeng Lu, Hui Zhang, Xuejie Gao, Shuaikang Chang, Huaping Wang, Xiaosong Wu, Dongliang Song, Guang Yang, Huabin Zhu, Jinfeng Zhou, Fenghuang Zhan, Weiliang Zhu, Jumei Shi, 2023
红景天苷通过抑制TNF-α/NF-κB通路改善C2C12细胞萎缩的研究, 莉萍陈, 艳蕾张, 梦玲马, 湘萍康, 勇张, 志建徐, 维良朱, 张斌龚, 2023

Molecular Simulation Drug Design Computational Chemistry Pharmacophore Virtual Screening Protein-Ligand Interaction Binding Affinity Molecular Dynamics Structure-Based Drug Design Lead Optimization

Qiang Shao - University of Chinese Academy of Sciences

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