Professor | 朱维良 | 数字化转型顾问

Name

朱维良

Contact Information

wlzhu@simm.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	1995-09--1998-04 博士学位: 中国科学院上海药物研究所 1986-09--1988-07 硕士学位: 苏州大学化学系 1979-09--1983-07 学士学位: 扬州大学化学化工学院
Work Experience	2009-04~现在 - 中国科学院上海药物研究所 - 药物发现与设计中心主任 2004-07~现在 - 中国科学院上海药物研究所 - 研究员、博士生导师 1998-05~2004-07 - 新加坡理工学院生命科学技术中心 - 讲师 1989-08~1995-08 - 扬州大学农学院 - 助教、讲师 1983-08~1986-08 - 扬州大学农学院 - 助教

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

Work Experience

Areas of Focus	分子模拟与药物设计药物化学
Publications	Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo, Sanfeng Dong, Ke Hu, Yulong Shi, Guanli Wang, Dandan Yu, Yitian Zhao, Hui Zhang, Yingcong Wang, Haiguo Sun, Zhijian Xu, Qi Jia, Yiming Li, Yingxia Li, Bo Li, Jumei Shi, Weiliang Zhu, 2024 Preferred microenvironments of halogen bonds and hydrogen bonds revealed using statistics and QM/MM calculation studies, Liping Zhou, Jintian Li, Yulong Shi, Leyun Wu, Weiliang Zhu, Zhijian Xu, 2023 Development of a Novel 18F-Labeled Probe for PET Imaging of Estrogen Receptor beta, Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Weiliang Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng, 2023 Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma, Li Xu, Yingcong Wang, Guanli Wang, Shushan Guo, Dandan Yu, Qilin Feng, Ke Hu, Gege Chen, Bo Li, Zhijian Xu, Xinyan Jia, Yumeng Lu, Hui Zhang, Xuejie Gao, Shuaikang Chang, Huaping Wang, Xiaosong Wu, Dongliang Song, Guang Yang, Huabin Zhu, Jinfeng Zhou, Fenghuang Zhan, Weiliang Zhu, Jumei Shi, 2023 红景天苷通过抑制TNF-α/NF-κB通路改善C2C12细胞萎缩的研究, 莉萍陈, 艳蕾张, 梦玲马, 湘萍康, 勇张, 志建徐, 维良朱, 张斌龚, 2023

Areas of Focus

分子模拟与药物设计
药物化学

Publications

Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo, Sanfeng Dong, Ke Hu, Yulong Shi, Guanli Wang, Dandan Yu, Yitian Zhao, Hui Zhang, Yingcong Wang, Haiguo Sun, Zhijian Xu, Qi Jia, Yiming Li, Yingxia Li, Bo Li, Jumei Shi, Weiliang Zhu, 2024
Preferred microenvironments of halogen bonds and hydrogen bonds revealed using statistics and QM/MM calculation studies, Liping Zhou, Jintian Li, Yulong Shi, Leyun Wu, Weiliang Zhu, Zhijian Xu, 2023
Development of a Novel 18F-Labeled Probe for PET Imaging of Estrogen Receptor beta, Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Weiliang Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng, 2023
Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma, Li Xu, Yingcong Wang, Guanli Wang, Shushan Guo, Dandan Yu, Qilin Feng, Ke Hu, Gege Chen, Bo Li, Zhijian Xu, Xinyan Jia, Yumeng Lu, Hui Zhang, Xuejie Gao, Shuaikang Chang, Huaping Wang, Xiaosong Wu, Dongliang Song, Guang Yang, Huabin Zhu, Jinfeng Zhou, Fenghuang Zhan, Weiliang Zhu, Jumei Shi, 2023
红景天苷通过抑制TNF-α/NF-κB通路改善C2C12细胞萎缩的研究, 莉萍陈, 艳蕾张, 梦玲马, 湘萍康, 勇张, 志建徐, 维良朱, 张斌龚, 2023

分子模拟药物设计计算化学药效团虚拟筛选蛋白质-配体相互作用结合亲和力分子动力学基于结构的药物设计先导化合物优化

贺云娇 - 南方科技大学

贺云娇 - 南方科技大学

罗成 - 中国科学院大学

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