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Guilong Zhao
Medical School
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Contact
Drug Chemistry Drug Synthesis Drug Discovery Development Pharmacology Medicinal Chemistry Synthesis Biological Evaluation Structure-Activity Relationship Pharmacophore Modeling
Areas of Focus
  • Drug Chemistry
  • Drug Synthesis Chemistry
  • Drug Discovery and Development
Academic Background & Achievements
  • 2005-09 to 2008-06 PhD: Shandong University
  • 2002-09 to 2005-06 Master's: Qingdao University of Science and Technology
  • 1999-09 to 2002-06 Bachelor's: Liaocheng University
Publications
  • Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel α2δ ligands for the treatment of chronic neuropathic pain, Guilong Zhao, 2023
  • Review of voltage-gated calcium channel α2δ subunit ligands for the treatment of chronic neuropathic pain and insight into structure-activity relationship (SAR) by pharmacophore modeling, Guilong Zhao, 2022
  • Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020), Jingwei Wu, Huan Zhang, Guilong Zhao, Runling Wang, 2021
  • Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout, Jingwei Wu, Ling Yin, Yuqiang Liu, Huan Zhang, Yafei Xie, Runling Wang, Guilong Zhao, 2019
  • Nickel-Catalyzed Amidoalkylation Reaction of gamma-Hydroxy Lactams: An Access to 3-Substituted Isoindolinones, Shuo Zhang, Xinhua Shi, Jichao Li, Zitong Hou, Zihe Song, Xiaofeng Su, Dan Peng, Feng Wang, Yitao Yu, Guilong Zhao, 2019
  • Release of Amino- or Carboxy-Containing Compounds Triggered by HOCl: Application for Imaging and Drug Design, Peng Wei, Lingyan Liu, Ying Wen, Guilong Zhao, Fengfeng Xue, Wei Yuan, Ruohan Li, Yaping Zhong, Mengfan Zhang, Tao Yi, 2019
  • Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor, Wenqing Cai, Jingwei Wu, Wei Liu, Yafei Xie, Yuqiang Liu, Shuo Zhang, Weiren Xu, Lida Tang, Jianwu Wang, Guilong Zhao, 2018
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