Professor | Jingdan Liang | Asia Growth Partners

Name	Jingdan Liang
Contact Information	jdliang@sjtu.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Jingdan Liang

Contact Information

jdliang@sjtu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	PhD from Shanghai Jiao Tong University Visiting scholar at the Department of Cell Biology, University of California, Berkeley (Feb 2011 - Feb 2013)
Work Experience	Current: Works at the State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University
Awards	Pujiang Plan Special Urgent Talent

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

PhD from Shanghai Jiao Tong University
Visiting scholar at the Department of Cell Biology, University of California, Berkeley (Feb 2011 - Feb 2013)

Work Experience

Current: Works at the State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University

Awards

Pujiang Plan Special Urgent Talent

Areas of Focus	Sulfur modification of DNA and its implications in oligonucleotide drugs Structural and mechanistic studies of natural product synthesis machinery using cryo-EM Physiological significance of DNA phosphorothioate modifications
Publications	C-N bond formation by a polyketide synthase, Liang J* et al., 2023 Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain, Liang J* et al., 2022 Structural basis for the biosynthesis of Lovastatin, Liang J et al., 2021 Phosphorothioated DNA is shielded from oxidative damage, Liang J et al., 2019 An in vitro DNA Phosphorothioate Modification Reaction, Liang J* et al., 2020 Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882, Liang J et al., 2018 Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882, Liang J et al., 2018 DNA Phosphorothioate Modification Plays a Role in Peroxides Resistance in Streptomyces lividans, Liang J* et al., 2016 Phosphorothioate DNA as an antioxidant in bacteria, Liang J et al., 2012 DNA modification by sulfur: analysis of the sequence recognition specificity surrounding the modification sites, Liang J et al., 2007

Areas of Focus

Sulfur modification of DNA and its implications in oligonucleotide drugs
Structural and mechanistic studies of natural product synthesis machinery using cryo-EM
Physiological significance of DNA phosphorothioate modifications

Publications

C-N bond formation by a polyketide synthase, Liang J* et al., 2023
Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain, Liang J* et al., 2022
Structural basis for the biosynthesis of Lovastatin, Liang J et al., 2021
Phosphorothioated DNA is shielded from oxidative damage, Liang J et al., 2019
An in vitro DNA Phosphorothioate Modification Reaction, Liang J* et al., 2020
Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882, Liang J et al., 2018
Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882, Liang J et al., 2018
DNA Phosphorothioate Modification Plays a Role in Peroxides Resistance in Streptomyces lividans, Liang J* et al., 2016
Phosphorothioate DNA as an antioxidant in bacteria, Liang J et al., 2012
DNA modification by sulfur: analysis of the sequence recognition specificity surrounding the modification sites, Liang J et al., 2007

Sulfur Dna Modification Oligonucleotide Drugs Cryo-Em Natural Products Synthesis Phosphorothioate Physiology

Zhijun Wang - Shanghai Jiao Tong University

Zhijun Wang - Shanghai Jiao Tong University

Xinyi He - Shanghai Jiao Tong University

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