Areas of Focus
- Synthetic machinery of natural products such as erythromycin and penicillin
- Synthetic machinery for lovastatin and related compounds
- Cryo-EM techniques for protein structure analysis
Work Experience
- 2007 - Present: Shanghai Jiao Tong University, Associate Researcher
Academic Background & Achievements
- 2007 - Present: Associate Researcher at the State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University
- 2011-2013: Tang Scholar at University of California, Berkeley
Publications
- C-N bond formation by a polyketide synthase, Wang J, Wang X, Li X, Kong L, Du Z, Li D, Gou L, Wu H, Cao W, Wang X, Lin S, Shi T, Deng Z, Wang Z, Liang J, 2023
- Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain, Wang J, Li D, Chen L, Cao W, Kong L, Zhang W, Croll T, Deng Z, Liang J, Wang Z, 2022
- Structural basis for the biosynthesis of Lovastatin, Wang J, Liang J, Chen L, Zhang W, Kong L, Peng C, Su C, Tang Y, Deng X, Wang Z, 2021
- An in vitro DNA Phosphorothioate Modification Reaction, Pu T, Mei Z, Zhang W, Liang W, Zhou X, Liang J, Deng Z, Wang Z, 2020
- Phosphorothioated DNA is shielded from oxidative damage, Pu T, Liang J, Mei Z, Yang Y, Wang J, Zhang W, Liang W, Zhou X, Deng Z, Wang Z, 2019
- Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882, Wu H, Liang J, Gou L, Wu Q, Liang W, Zhou X, Bruce IJ, Deng Z, Wang Z, 2018
- Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882, Wu H, Liang J, Wang J, Liang W, Gou L, Wu Q, Zhou X, Bruce IJ, Deng Z, Wang Z, 2018
- CRISPR/dCas9-Mediated Multiplex Gene Repression in Streptomyces, Zhao Y, Li L, Zheng G, Jiang W, Deng Z, Wang Z, Lu Y, 2018
- Phosphorothioate DNA as an antioxidant in bacteria, Xie X, Liang J, Pu T, Xu F, Yao F, Yang Y, Zhao Y, You D, Zhou X, Deng Z, Wang Z, 2012
- DNA modification by sulfur: analysis of the sequence recognition specificity surrounding the modification sites, Liang J, Wang Z, He X, Li J, Zhou X, Deng Z, 2007
