Mancheng Tang
Life Science
Shanghai Jiao Tong University
Shanghai
Language: Chinese, English
Contact
Biocontrol Trichoderma Genome Mining Heterologous Expression Natural Products Biosynthesis Enzymatic Mechanisms Synthetic Biology Chiral Centers Microbial Synthesis
Areas of Focus
  • Discovery of bioactive natural products
  • Biosynthesis and creation of natural products
  • Microbial creation of high-value small molecule chemicals
Work Experience
  • 2019.02-present: Shanghai Jiao Tong University, School of Life Sciences and Biotechnology, Associate Professor, Doctoral Supervisor
  • 2014.02-2018.08: University of California, Los Angeles, Postdoctoral Researcher
  • 2013.05-2014.01: Shanghai Institute of Organic Chemistry, CAS, Associate Researcher
  • 2010.07-2013.05: Shanghai Institute of Organic Chemistry, CAS, Assistant Researcher
Academic Background & Achievements
  • 2004-2010: PhD, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
  • 1999-2003: Bachelor, College of Chemistry and Molecular Sciences, Wuhan University
Publications
  • Genome Mining Discovery of a New Benzazepine Alkaloid Pseudofisnin A from the Marine Fungus Neosartorya pseudofischeri F27-1., Xue X.-X., Chen L., Tang M.-C.*, 2022
  • Discovery and Biosynthesis of Macrophasetins from the Plant Pathogen Fungus Macrophomina phaseolina., Yu C., Chen L., Gao Y.-L., Liu J., Li P.-L., Zhang M.-L., Li Q., Zhang H.-D.*, Tang M.-C.*, Li L.*, 2022
  • Combinatorial Biosynthesis of Terpenoids through Mixing-and-Matching Sesquiterpene Cyclase and Cytochrome P450 Pairs., Tang M.-C., Shen C., Deng Z., Ohashi M., Tang Y.*, 2022
  • Fungal Highly Reducing Polyketide Synthases Biosynthesize Salicylaldehydes that are Precursors to Epoxycyclohexenol Natural Products., Liu L., Tang M.-C.*, Tang Y.*, 2019
  • Genome-mined Diels-Alderase catalyzes the formation of the cis-octahydrodecalins of varicidin A and B., Tan D., Jamieson C. S., Ohashi M., Tang M.-C.*, Houk K. N.*, Tang Y.*, 2019
  • Thioesterase-catalyzed aminoacylation and thiolation of polyketides in fungi., Tang M.-C., Fischer C. R., Chari J. V., Tan D., Suresh S., Chu A., Miranda M., Smith J., Zhang Z., Garg N., St Onge R. P.*, Tang Y.*, 2019
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