Areas of Focus
- 活性新天然产物的发掘
- 天然产物生物合成与创制
- 高附加值小分子化学品的微生物创制
Work Experience
- 2019.02-至今: 上海交通大学生命科学技术学院，长聘教轨副教授，博导
- 2014.02-2018.08: 美国加州大学洛杉矶分校，博士后
- 2013.05-2014.01: 中科院上海有机化学研究所，副研究员
- 2010.07-2013.05: 中科院上海有机化学研究所，助理研究员
Academic Background & Achievements
- 2004-2010: 博士, 中国科学院上海有机化学研究所
- 1999-2003: 学士, 武汉大学化学与分子科学学院
Publications
- Xue X.-X., Chen L., Tang M.-C.* “Genome Mining Discovery of a New Benzazepine Alkaloid Pseudofisnin A from the Marine Fungus Neosartorya pseudofischeri F27-1.” Antibiotics (Basel) 2022, 11, 1444., Xue X.-X., Chen L., Tang M.-C.*, 2022
- Yu C.#, Chen L.#, Gao Y.-L., Liu J., Li P.-L., Zhang M.-L., Li Q., Zhang H.-D.*, Tang M.-C.*, Li L.* “Discovery and Biosynthesis of Macrophasetins from the Plant Pathogen Fungus Macrophomina phaseolina.” Front. Microbiol. 2022, 13, 1056392., Yu C., Chen L., Gao Y.-L., Liu J., Li P.-L., Zhang M.-L., Li Q., Zhang H.-D.*, Tang M.-C.*, Li L.*, 2022
- Tang M.-C., Shen C., Deng Z., Ohashi M., Tang Y.* “Combinatorial Biosynthesis of Terpenoids through Mixing-and-Matching Sesquiterpene Cyclase and Cytochrome P450 Pairs.” Org. Lett. 2022, 24, 4783-4787., Tang M.-C., Shen C., Deng Z., Ohashi M., Tang Y.*, 2022
- Liu L., Tang M.-C.*, Tang Y.* “Fungal Highly Reducing Polyketide Synthases Biosynthesize Salicylaldehydes that are Precursors to Epoxycyclohexenol Natural Products.” J. Am. Chem. Soc. 2019, 141, 19538-19541., Liu L., Tang M.-C.*, Tang Y.*, 2019
- Tan D.#, Jamieson C. S.#, Ohashi M., Tang M.-C.*, Houk K. N.*, Tang Y.* “Genome-mined Diels-Alderase catalyzes the formation of the cis-octahydrodecalins of varicidin A and B.” J. Am. Chem. Soc. 2019,141, 769-773., Tan D., Jamieson C. S., Ohashi M., Tang M.-C.*, Houk K. N.*, Tang Y.*, 2019
- Tang M.-C.#, Fischer C. R.#, Chari J. V., Tan D., Suresh S., Chu A., Miranda M., Smith J., Zhang Z., Garg N., St Onge R. P.*, Tang Y.* “Thioesterase-catalyzed aminoacylation and thiolation of polyketides in fungi.” J. Am. Chem. Soc. 2019, 141, 8198-8206., Tang M.-C., Fischer C. R., Chari J. V., Tan D., Suresh S., Chu A., Miranda M., Smith J., Zhang Z., Garg N., St Onge R. P.*, Tang Y.*, 2019
