Professor | Yong Zhang | Asia Growth Partners

Name	Yong Zhang
Contact Information	yzhang2011@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

Name

Yong Zhang

Contact Information

yzhang2011@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	Bachelor: Xinjiang University Master: Shanghai Institute of Materia Medica, Chinese Academy of Sciences PhD: Fudan University, Molecular Genetics and Biochemistry Postdoctoral Researcher: University of Texas at Austin Visiting Scholar: Michigan State University
Work Experience	Current - Shanghai Jiao Tong University - Associate Researcher
Awards	2019: Jiangsu Province Yangzhong Innovative Talent 'Jiang Yan Plan'

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

Bachelor: Xinjiang University
Master: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
PhD: Fudan University, Molecular Genetics and Biochemistry
Postdoctoral Researcher: University of Texas at Austin
Visiting Scholar: Michigan State University

Work Experience

Current - Shanghai Jiao Tong University - Associate Researcher

Awards

2019: Jiangsu Province Yangzhong Innovative Talent 'Jiang Yan Plan'

Areas of Focus	Enzyme molecular design and cascade enzyme system assembly Protein structure analysis and molecular mechanism elucidation Inhibitor design and synthesis
Publications	Ordered Coimmobilization of Multimeric Enzyme Arrays with Enhanced Biocatalytic Cascade Performance, Mohamed Yassin Ali, Qing Chang, Yuerong Su, Jinhong Wu, Quande Yan, Liang Yin, Yong Zhang, and Yan Feng, 2021 Highly Efficient Biosynthesis of Glycyrrhetinic Acid Glycoside Derivatives Using an Artificial Biocatalyst Cascade, Mohamed Yassin Ali, Qing Chang, Guo Xiang, Yong Zhang, Yan Feng, 2021 Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method, Yumeng Tan, Yong Zhang, Yunbin Han, Hao Liu, Haifeng Chen, Fuqiang Ma, Stephen G Withers, Yan Feng, Guangyu Yang, 2019 Structure of an Endogalactosylceramidase from Rhodococcus hoagii 103S Reveals the Molecular Basis of its Substrate Specificity, Liuqing Chen, Qing Chang, Guangyu Yang, Yong Zhang, Yan Feng, 2019 Self-Assembled Multimeric-Enzyme Nanoreactor for Robust and Efficient Biocatalysis, Liang Yin, Xiang Guo, Lu Liu, Yong Zhang, Yan Feng, 2018 Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions, Md Anarul Hoque, Yong Zhang, Liuqing Chen, Guangyu Yang, Mst Afroza Khatun, Haifeng Chen, Liu Hao, Yan Feng, 2017 Structure features of GH10 xylanase from Caldicellulosiruptor bescii: implication for its thermophilic adaption and substrate binding preference, Yong Zhang, Jiao An, Guangyu Yang, Xiaofei Zhang, Yuan Xie, Liuqing Chen, Yan Feng, 2016 Synthesis, biological evaluation and molecular docking of 2-phenyl- benzo[d] oxazole- 7-carboxamide derivatives as potential Staphylococcus aureus sortaseA inhibitors, Yong Zhang, Jian Bao, Xinxian Deng, Wan He, Jiajun Fan, Lei Fu, 2016 Synthesis, biological evaluation and molecular docking analysis of 2-phenyl-benzofuran-3-carboxamide as a potential inhibitors of Sortase A, Wan He, Yong Zhang, Jian Bao, Xinxian Deng, Jennifer Batara, Shawn Casey, Faqin Jiang, Lei Fu, 2016 Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue, Yong Zhang, Mengmeng Zhang and Yan Zhang*, 2011

Areas of Focus

Enzyme molecular design and cascade enzyme system assembly
Protein structure analysis and molecular mechanism elucidation
Inhibitor design and synthesis

Publications

Ordered Coimmobilization of Multimeric Enzyme Arrays with Enhanced Biocatalytic Cascade Performance, Mohamed Yassin Ali, Qing Chang, Yuerong Su, Jinhong Wu, Quande Yan, Liang Yin, Yong Zhang*, and Yan Feng*, 2021
Highly Efficient Biosynthesis of Glycyrrhetinic Acid Glycoside Derivatives Using an Artificial Biocatalyst Cascade, Mohamed Yassin Ali, Qing Chang, Guo Xiang, Yong Zhang*, Yan Feng*, 2021
Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method, Yumeng Tan, Yong Zhang, Yunbin Han, Hao Liu, Haifeng Chen, Fuqiang Ma, Stephen G Withers, Yan Feng, Guangyu Yang*, 2019
Structure of an Endogalactosylceramidase from Rhodococcus hoagii 103S Reveals the Molecular Basis of its Substrate Specificity, Liuqing Chen, Qing Chang, Guangyu Yang, Yong Zhang*, Yan Feng*, 2019
Self-Assembled Multimeric-Enzyme Nanoreactor for Robust and Efficient Biocatalysis, Liang Yin, Xiang Guo, Lu Liu, Yong Zhang*, Yan Feng*, 2018
Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions, Md Anarul Hoque, Yong Zhang, Liuqing Chen, Guangyu Yang, Mst Afroza Khatun, Haifeng Chen, Liu Hao, Yan Feng*, 2017
Structure features of GH10 xylanase from Caldicellulosiruptor bescii: implication for its thermophilic adaption and substrate binding preference, Yong Zhang, Jiao An, Guangyu Yang, Xiaofei Zhang, Yuan Xie, Liuqing Chen, Yan Feng*, 2016
Synthesis, biological evaluation and molecular docking of 2-phenyl- benzo[d] oxazole- 7-carboxamide derivatives as potential Staphylococcus aureus sortaseA inhibitors, Yong Zhang, Jian Bao, Xinxian Deng, Wan He, Jiajun Fan, Lei Fu*, 2016
Synthesis, biological evaluation and molecular docking analysis of 2-phenyl-benzofuran-3-carboxamide as a potential inhibitors of Sortase A, Wan He, Yong Zhang, Jian Bao, Xinxian Deng, Jennifer Batara, Shawn Casey, Faqin Jiang*, Lei Fu*, 2016
Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue, Yong Zhang, Mengmeng Zhang and Yan Zhang*, 2011

Enzyme Design Biocatalysis Protein Engineering Molecular Dynamics X-Ray Crystallography Substrate Specificity Cascade Reactions Biochemical Analysis Molecular Design Inhibitor Synthesis

Guangyu Yang - Shanghai Jiao Tong University

Guangyu Yang - Shanghai Jiao Tong University

Yong Zhang - Shanghai Jiao Tong University

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