Professor | Jie Sun | Asia Growth Partners

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Name	Jie Sun
Contact Information	sunjiehm@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

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Name

Jie Sun

Contact Information

sunjiehm@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2014.2-2017.6 PhD in Oncology: Zhejiang University School of Medicine (Joint training at City of Hope National Medical Center, USA from 2015.10-2017.6) 2007.9-2010.3 Master's in Oncology: Zhejiang University School of Medicine 2003.9-2007.6 Bachelor's in Biotechnology: Zhejiang University School of Life Sciences
Work Experience	2021.2-present - Zhejiang University School of Medicine - Researcher under the Hundred Talents Program 2019.4-2020.12 - City of Hope National Medical Center, USA - Staff Scientist 2017.6-2019.4 - City of Hope National Medical Center, USA - Postdoctoral Fellow
Awards	ASH abstract Achievement Award (2017): American Society of Hematology ASH abstract Achievement Award (2016): American Society of Hematology Third Prize of Zhejiang Provincial Natural Science Award (2016) Second Prize of Zhejiang Provincial Natural Science Award (2020)

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2014.2-2017.6 PhD in Oncology: Zhejiang University School of Medicine (Joint training at City of Hope National Medical Center, USA from 2015.10-2017.6)
2007.9-2010.3 Master's in Oncology: Zhejiang University School of Medicine
2003.9-2007.6 Bachelor's in Biotechnology: Zhejiang University School of Life Sciences

Work Experience

2021.2-present - Zhejiang University School of Medicine - Researcher under the Hundred Talents Program
2019.4-2020.12 - City of Hope National Medical Center, USA - Staff Scientist
2017.6-2019.4 - City of Hope National Medical Center, USA - Postdoctoral Fellow

Awards

ASH abstract Achievement Award (2017): American Society of Hematology
ASH abstract Achievement Award (2016): American Society of Hematology
Third Prize of Zhejiang Provincial Natural Science Award (2016)
Second Prize of Zhejiang Provincial Natural Science Award (2020)

Areas of Focus	Epigenetic regulation of malignant hematologic tumors
Publications	SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L, 2018 Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells, Wang H, Sun J, Zhang B, Zhao D, Tong H, Wu H, Li X, Luo Y, Dong D, Yao Y, McDonald T, Stein AS, Al Malki MM, Pichiorri F, Carlesso N, Kuo YH, Marcucci G, Li L, Jin J, 2021 HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML, Huang F, Sun J, Chen W, He X, Zhu Y, Dong H, Wang H, Li Z, Zhang L, Khaled S, Marcucci G, Huang J, Li L, 2020 Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion, Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Müschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J, 2020 Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia, Zhu Y, He X, Lin YC, Dong H, Zhang L, Chen X, Wang Z, Shen Y, Li M, Wang H, Sun J, Nguyen LX, Zhang H, Jiang W, Yang Y, Chen J, Müschen M, Chen CW, Konopleva MY, Sun W, Jin J, Carlesso N, Marcucci G, Luo Y, Li L, 2019 PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia, He X, Zhu Y, Lin YC, Li M, Du J, Dong H, Sun J, Zhu L, Wang H, Ding Z, Zhang L, Zhang L, Zhao D, Wang Z, Wu H, Zhang H, Jiang W, Xu Y, Jin J, Shen Y, Perry J, Zhao X, Zhang B, Liu S, Xue SL, Shen B, Chen CW, Chen J, Khaled S, Kuo YH, Marcucci G, Luo Y, Li L, 2019

Areas of Focus

Epigenetic regulation of malignant hematologic tumors

Publications

SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L, 2018
Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells, Wang H, Sun J*, Zhang B, Zhao D, Tong H, Wu H, Li X, Luo Y, Dong D, Yao Y, McDonald T, Stein AS, Al Malki MM, Pichiorri F, Carlesso N, Kuo YH, Marcucci G, Li L, Jin J, 2021
HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML, Huang F, Sun J*, Chen W, He X, Zhu Y, Dong H, Wang H, Li Z, Zhang L, Khaled S, Marcucci G, Huang J, Li L, 2020
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion, Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Müschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J, 2020
Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia, Zhu Y, He X, Lin YC, Dong H, Zhang L, Chen X, Wang Z, Shen Y, Li M, Wang H, Sun J, Nguyen LX, Zhang H, Jiang W, Yang Y, Chen J, Müschen M, Chen CW, Konopleva MY, Sun W, Jin J, Carlesso N, Marcucci G, Luo Y, Li L, 2019
PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia, He X, Zhu Y, Lin YC, Li M, Du J, Dong H, Sun J, Zhu L, Wang H, Ding Z, Zhang L, Zhang L, Zhao D, Wang Z, Wu H, Zhang H, Jiang W, Xu Y, Jin J, Shen Y, Perry J, Zhao X, Zhang B, Liu S, Xue SL, Shen B, Chen CW, Chen J, Khaled S, Kuo YH, Marcucci G, Luo Y, Li L, 2019

Epigenetics Hematologic Tumors Malignancy Regulation Cancer Stem Cells Progenitor Cells Tet2 Sirt1 Mds

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