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Jie Sun
Medical School
Zhejiang University
Zhejiang
Language: English, Chinese
Epigenetics
Hematologic Tumors
Malignancy
Regulation
Cancer
Stem Cells
Progenitor Cells
Tet2
Sirt1
Mds
Areas of Focus
- Epigenetic regulation of malignant hematologic tumors
Work Experience
- 2021.2-present - Zhejiang University School of Medicine - Researcher under the Hundred Talents Program
- 2019.4-2020.12 - City of Hope National Medical Center, USA - Staff Scientist
- 2017.6-2019.4 - City of Hope National Medical Center, USA - Postdoctoral Fellow
Academic Background & Achievements
- 2014.2-2017.6 PhD in Oncology: Zhejiang University School of Medicine (Joint training at City of Hope National Medical Center, USA from 2015.10-2017.6)
- 2007.9-2010.3 Master's in Oncology: Zhejiang University School of Medicine
- 2003.9-2007.6 Bachelor's in Biotechnology: Zhejiang University School of Life Sciences
Publications
- SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L, 2018
- Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells, Wang H, Sun J*, Zhang B, Zhao D, Tong H, Wu H, Li X, Luo Y, Dong D, Yao Y, McDonald T, Stein AS, Al Malki MM, Pichiorri F, Carlesso N, Kuo YH, Marcucci G, Li L, Jin J, 2021
- HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML, Huang F, Sun J*, Chen W, He X, Zhu Y, Dong H, Wang H, Li Z, Zhang L, Khaled S, Marcucci G, Huang J, Li L, 2020
- Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion, Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Müschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J, 2020
- Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia, Zhu Y, He X, Lin YC, Dong H, Zhang L, Chen X, Wang Z, Shen Y, Li M, Wang H, Sun J, Nguyen LX, Zhang H, Jiang W, Yang Y, Chen J, Müschen M, Chen CW, Konopleva MY, Sun W, Jin J, Carlesso N, Marcucci G, Luo Y, Li L, 2019
- PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia, He X, Zhu Y, Lin YC, Li M, Du J, Dong H, Sun J, Zhu L, Wang H, Ding Z, Zhang L, Zhang L, Zhao D, Wang Z, Wu H, Zhang H, Jiang W, Xu Y, Jin J, Shen Y, Perry J, Zhao X, Zhang B, Liu S, Xue SL, Shen B, Chen CW, Chen J, Khaled S, Kuo YH, Marcucci G, Luo Y, Li L, 2019
Awards
- ASH abstract Achievement Award (2017): American Society of Hematology
- ASH abstract Achievement Award (2016): American Society of Hematology
- Third Prize of Zhejiang Provincial Natural Science Award (2016)
- Second Prize of Zhejiang Provincial Natural Science Award (2020)
