Professor | 孙杰 | 数字化转型顾问

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Name	孙杰
Contact Information	sunjiehm@zju.edu.cn
Language ability	英语, 中文
Province	浙江

Upload Avatar (500 x 500)

Name

孙杰

Contact Information

sunjiehm@zju.edu.cn

Language ability

英语, 中文

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Medical
Academic Background & Achievements	2014.2-2017.6 浙江大学医学院肿瘤学专业博士 (2015.10-2017.6在美国希望之城国家医学中心联合培养) 2007.9-2010.3 浙江大学医学院肿瘤学专业硕士 2003.9-2007.6 浙江大学生命科学院生物技术专业学士
Work Experience	2021.2至今 - 浙江大学医学院 - 百人计划研究员 2019.4-2020.12 - 美国希望之城国家医学中心 - Staff Scientist 2017.6-2019.4 - 美国希望之城国家医学中心 - 博士后
Awards	ASH abstract Achievement Award (2017): 美国血液学会 ASH abstract Achievement Award (2016): 美国血液学会浙江省自然科学奖三等奖 (2016) 浙江省自然科学奖二等奖 (2020)

University/Lab Affiliation and Title

浙江大学

Faculty

Medical

Academic Background & Achievements

2014.2-2017.6 浙江大学医学院肿瘤学专业博士 (2015.10-2017.6在美国希望之城国家医学中心联合培养)
2007.9-2010.3 浙江大学医学院肿瘤学专业硕士
2003.9-2007.6 浙江大学生命科学院生物技术专业学士

Work Experience

2021.2至今 - 浙江大学医学院 - 百人计划研究员
2019.4-2020.12 - 美国希望之城国家医学中心 - Staff Scientist
2017.6-2019.4 - 美国希望之城国家医学中心 - 博士后

Awards

ASH abstract Achievement Award (2017): 美国血液学会
ASH abstract Achievement Award (2016): 美国血液学会
浙江省自然科学奖三等奖 (2016)
浙江省自然科学奖二等奖 (2020)

Areas of Focus	恶性血液系统肿瘤的表观遗传调控
Publications	SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L, 2018 Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells, Wang H, Sun J, Zhang B, Zhao D, Tong H, Wu H, Li X, Luo Y, Dong D, Yao Y, McDonald T, Stein AS, Al Malki MM, Pichiorri F, Carlesso N, Kuo YH, Marcucci G, Li L, Jin J, 2021 HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML, Huang F, Sun J, Chen W, He X, Zhu Y, Dong H, Wang H, Li Z, Zhang L, Khaled S, Marcucci G, Huang J, Li L, 2020 Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion, Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Müschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J, 2020 Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia, Zhu Y, He X, Lin YC, Dong H, Zhang L, Chen X, Wang Z, Shen Y, Li M, Wang H, Sun J, Nguyen LX, Zhang H, Jiang W, Yang Y, Chen J, Müschen M, Chen CW, Konopleva MY, Sun W, Jin J, Carlesso N, Marcucci G, Luo Y, Li L, 2019 PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia, He X, Zhu Y, Lin YC, Li M, Du J, Dong H, Sun J, Zhu L, Wang H, Ding Z, Zhang L, Zhang L, Zhao D, Wang Z, Wu H, Zhang H, Jiang W, Xu Y, Jin J, Shen Y, Perry J, Zhao X, Zhang B, Liu S, Xue SL, Shen B, Chen CW, Chen J, Khaled S, Kuo YH, Marcucci G, Luo Y, Li L, 2019

Areas of Focus

恶性血液系统肿瘤的表观遗传调控

Publications

SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L, 2018
Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells, Wang H, Sun J*, Zhang B, Zhao D, Tong H, Wu H, Li X, Luo Y, Dong D, Yao Y, McDonald T, Stein AS, Al Malki MM, Pichiorri F, Carlesso N, Kuo YH, Marcucci G, Li L, Jin J, 2021
HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML, Huang F, Sun J*, Chen W, He X, Zhu Y, Dong H, Wang H, Li Z, Zhang L, Khaled S, Marcucci G, Huang J, Li L, 2020
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion, Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Müschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J, 2020
Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia, Zhu Y, He X, Lin YC, Dong H, Zhang L, Chen X, Wang Z, Shen Y, Li M, Wang H, Sun J, Nguyen LX, Zhang H, Jiang W, Yang Y, Chen J, Müschen M, Chen CW, Konopleva MY, Sun W, Jin J, Carlesso N, Marcucci G, Luo Y, Li L, 2019
PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia, He X, Zhu Y, Lin YC, Li M, Du J, Dong H, Sun J, Zhu L, Wang H, Ding Z, Zhang L, Zhang L, Zhao D, Wang Z, Wu H, Zhang H, Jiang W, Xu Y, Jin J, Shen Y, Perry J, Zhao X, Zhang B, Liu S, Xue SL, Shen B, Chen CW, Chen J, Khaled S, Kuo YH, Marcucci G, Luo Y, Li L, 2019

表观遗传学血液肿瘤恶性调控癌症干细胞祖细胞 Tet2 Sirt1 Mds

钱鹏旭 - 浙江大学

Area of Focus
干细胞 | 造血 | 血液 | 再生 | 移植 | 表观遗传调控 | 基因表达 | 癌症 | 治疗 | 纳米技术

黄建 - 浙江大学

尹亚飞 - 浙江大学

Area of Focus
非编码Rna | 染色质 | 基因表达 | 干细胞 | 分化 | 超级增强子 | Lncrna | 调控 | 转录 | 多能性

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