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孙杰
Medical School
浙江大学
浙江
Language: 英语, 中文
表观遗传学
血液肿瘤
恶性
调控
癌症
干细胞
祖细胞
Tet2
Sirt1
Mds
Areas of Focus
- 恶性血液系统肿瘤的表观遗传调控
Work Experience
- 2021.2至今 - 浙江大学医学院 - 百人计划研究员
- 2019.4-2020.12 - 美国希望之城国家医学中心 - Staff Scientist
- 2017.6-2019.4 - 美国希望之城国家医学中心 - 博士后
Academic Background & Achievements
- 2014.2-2017.6 浙江大学医学院肿瘤学专业博士 (2015.10-2017.6在美国希望之城国家医学中心联合培养)
- 2007.9-2010.3 浙江大学医学院肿瘤学专业硕士
- 2003.9-2007.6 浙江大学生命科学院生物技术专业学士
Publications
- SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function, Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L, 2018
- Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells, Wang H, Sun J*, Zhang B, Zhao D, Tong H, Wu H, Li X, Luo Y, Dong D, Yao Y, McDonald T, Stein AS, Al Malki MM, Pichiorri F, Carlesso N, Kuo YH, Marcucci G, Li L, Jin J, 2021
- HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML, Huang F, Sun J*, Chen W, He X, Zhu Y, Dong H, Wang H, Li Z, Zhang L, Khaled S, Marcucci G, Huang J, Li L, 2020
- Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion, Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, Qin X, Prince E, Xie J, Qin H, Li W, Shen C, Sun J, Kulkarni P, Weng H, Huang H, Chen Z, Zhang B, Wu X, Olsen MJ, Müschen M, Marcucci G, Salgia R, Li L, Fathi AT, Li Z, Mulloy JC, Wei M, Horne D, Chen J, 2020
- Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL-rearranged acute lymphoblastic leukemia, Zhu Y, He X, Lin YC, Dong H, Zhang L, Chen X, Wang Z, Shen Y, Li M, Wang H, Sun J, Nguyen LX, Zhang H, Jiang W, Yang Y, Chen J, Müschen M, Chen CW, Konopleva MY, Sun W, Jin J, Carlesso N, Marcucci G, Luo Y, Li L, 2019
- PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia, He X, Zhu Y, Lin YC, Li M, Du J, Dong H, Sun J, Zhu L, Wang H, Ding Z, Zhang L, Zhang L, Zhao D, Wang Z, Wu H, Zhang H, Jiang W, Xu Y, Jin J, Shen Y, Perry J, Zhao X, Zhang B, Liu S, Xue SL, Shen B, Chen CW, Chen J, Khaled S, Kuo YH, Marcucci G, Luo Y, Li L, 2019
Awards
- ASH abstract Achievement Award (2017): 美国血液学会
- ASH abstract Achievement Award (2016): 美国血液学会
- 浙江省自然科学奖三等奖 (2016)
- 浙江省自然科学奖二等奖 (2020)
