Bachelor's Degree in Bioinformatics: Harbin Medical University
Master's Degree in Cell Biology: Zhejiang University, Mentor: Professor Tianhua Zhou
Ph.D. in Cell Biology: Zhejiang University, Mentor: Researcher Saiyong Zhu
2023-08 - Present: Assistant Researcher at National Engineering Research Center Laboratory, Zhejiang University School of Medicine Affiliated Sir Run Run Shaw Hospital
Research
Potential Mechanisms of Transposable Elements in Hepatobiliary Malignancies Immunometabolic Microenvironment in Hepatobiliary Malignancies Epigenetic Mapping in Malignant Tumors
N-acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling, Zhensheng Hu#, Yunkun Lu#, Jie Cao#, Lianyu Lin#, Xi Chen, Ziyu Zhou, Jiaqi Pu, Guo Chen, Xiaojie Ma, Qian Deng, Yan Jin, Liling Jiang, Yuhan Li, Tengwei Li, Jianzhao Liu* & Saiyong Zhu*, 2024
ACLS4 could be a potential therapeutic target for severe acute pancreatitis, Feng Guo#, Yunkun Lu#, Lijun Du, Xiuliu Guo, Jinyan Xie* & Xiujun Cai*, 2024
A fast chemical reprogramming system promotes cell identity transition through a diapause-like state, Xi Chen#, Yunkun Lu#, Leyun Wang, Xiaojie Ma, Jiaqi Pu, Lianyu Lin, Qian Deng, Yuhan Li, Weiyun Wang, Yan Jin, Zhensheng Hu, Ziyu Zhou, Guo Chen, Liling Jiang, Hao Wang, Xiaoyang Zhao, Xiangwei He, Junfen Fu, Holger A. Russ, Wei Li & Saiyong Zhu*, 2023
Harnessing endogenous transcription factors directly by small molecules for chemically induced pluripotency inception, Yan Jin#, Yunkun Lu# , Lianyu Lin, Chao Liu, Xiaojie Ma, Xi Chen, Ziyu Zhou, Zhensheng Hu, Jiaqi Pu, Guo Chen, Qian Deng, Liling Jiang, Yuhan Li, Yulong Zhao, Hao Wang, Junfen Fu, Wei Li & Saiyong Zhu*, 2023
N6-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis, Xiaojie Ma#, Jie Cao#, Ziyu Zhou#, Yunkun Lu#, Qin Li, Yan Jin, Guo Chen, Weiyun Wang, Wenyan Ge, Xi Chen, Zhensheng Hu, Xiao Shu, Qian Deng, Jiaqi Pu, Chengzhen Liang, Junfen Fu, Jianzhao Liu* & Saiyong Zhu*, 2022
MiR-95-3p acts as a prognostic marker and promotes cervical cancer progression by targeting VCAM1, Sijie Feng#, Yunkun Lu#, Lisha Sun#, Shuangying Hao, Zhiqiang Liu, Fangyuan Yang, Lin Zhang, Ting Wang, Lihong Jiang, Juan Zhang, Shuyan Liu, Hui Pang, Zhenhui Wang* & Hong Wang*, 2022
Exploring specific prognostic biomarkers in triple-negative breast cancer, Chang Bao#, Yunkun Lu#, Jishun Chen#, Danni Chen, Weiyang Lou, Bisha Ding, Liang Xu & Weimin Fan*, 2019
Identification of prognostic biomarkers for cervical cancer based on programmed cell death-related genes and assessment of their immune profile and response to drug therapy, Sijie Feng, Zhenhui Wang, Huizhen Zhang, Baohua Hou, Yanjun Xu, Shuangying Hao* & Yunkun Lu*, 2023
CEP20 promotes invasion and metastasis of non-small cell lung cancer cells by depolymerizing microtubules, Sijie Feng#, Shuai Yuan#, Baohua Hou, Zhiqiang Liu, Yanjun Xu, Shuangying Hao* & Yunkun Lu*, 2023
The phase separation of extracellular matrix protein matrilin-3 from cancer-associated fibroblasts contributes to gastric cancer invasion, Yuliang Huang#, Xiaoyang Xu#, Yunkun Lu, Qiang Sun, Lu Zhang, Jiaqi Shao, Dingwei Chen, Yongxia Chang, Xiaoxia Sun, Wei Zhuo*, Tianhua Zhou*, 2024
Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production, Weiyun Wang, Shaofang Ren, Yunkun Lu, Xi Chen, Juanjuan Qu, Xiaojie Ma, Qian Deng, Zhensheng Hu, Yan Jin, Ziyu Zhou, Wenyan Ge, Yibing Zhu, Nannan Yang, Qin Li, Jiaqi Pu, Guo Chen, Cunqi Ye, Hao Wang, Xiaoyang Zhao, Zhiqiang Liu & Saiyong Zhu*, 2021
MiR-93 suppresses tumorigenesis and enhances chemosensitivity of breast cancer via dual targeting E2F1 and CCND, Chang Bao#, Jishun Chen#, Danni Chen, Yunkun Lu, Weiyang Lou, Bisha Ding, Liang Xu & Weimin Fan*, 2020
MiR-129-5p induces cell cycle arrest through modulating HOXC10/Cyclin D1 to inhibit gastric cancer progression, Jiamin He, Qiwei Ge, Zhenghua Lin, Weiyi Shen, Renbin Lin, Jiaguo Wu, Boya Wang, Yunkun Lu, Luyi Chen, Xiaosun Liu, Wenfang Zheng, Ying Zhang, Lan Wang, Kan Wang, Liangjing Wang, Wei Zhuo* & Shujie Chen*, 2020
NudC-like protein 2 restrains centriole amplification by stabilizing HERC2, Min Li, Xiaoyang Xu, Jun Zhang, Min Liu, Wei Wang, Ya Gao, Qiang Sun, Jiayu Zhang, Yunkun Lu, Fangwei Wang, Wei Liu & Tianhua Zhou*, 2019
微丝的信号调控机制和体内功能, 陆云昆，谢珊珊，周天华*, 2019
Keywords
Transposable ElementsHepatobiliary MalignanciesImmunometabolismMicroenvironmentEpigeneticsTumor ProgressionBioinformaticsMulti-OmicsCell BiologyCancer Research
