Professor | 陆云昆 | 数字化转型顾问

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Name	陆云昆
Contact Information	kevenloo1@zju.edu.cn
Language ability	中文, 英文
Province	浙江

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Name

陆云昆

Contact Information

kevenloo1@zju.edu.cn

Language ability

中文, 英文

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Medical
Academic Background & Achievements	本科生物信息学: 哈尔滨医科大学硕士细胞生物学: 浙江大学, 导师: 周天华教授博士细胞生物学: 浙江大学, 导师: 祝赛勇研究员
Work Experience	2023-08 - 至今: 助理研究员, 浙江大学医学院附属邵逸夫医院国家工程研究中心实验室

University/Lab Affiliation and Title

浙江大学

Faculty

Medical

Academic Background & Achievements

本科生物信息学: 哈尔滨医科大学
硕士细胞生物学: 浙江大学, 导师: 周天华教授
博士细胞生物学: 浙江大学, 导师: 祝赛勇研究员

Work Experience

2023-08 - 至今: 助理研究员, 浙江大学医学院附属邵逸夫医院国家工程研究中心实验室

Areas of Focus	肝胆恶性肿瘤中转座元件的潜在作用机制研究肝胆恶性肿瘤中免疫代谢微环境恶性肿瘤中表观遗传图谱构建
Publications	N-acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling, Zhensheng Hu#, Yunkun Lu#, Jie Cao#, Lianyu Lin#, Xi Chen, Ziyu Zhou, Jiaqi Pu, Guo Chen, Xiaojie Ma, Qian Deng, Yan Jin, Liling Jiang, Yuhan Li, Tengwei Li, Jianzhao Liu* & Saiyong Zhu, 2024 ACLS4 could be a potential therapeutic target for severe acute pancreatitis, Feng Guo#, Yunkun Lu#, Lijun Du, Xiuliu Guo, Jinyan Xie & Xiujun Cai, 2024 A fast chemical reprogramming system promotes cell identity transition through a diapause-like state, Xi Chen#, Yunkun Lu#, Leyun Wang, Xiaojie Ma, Jiaqi Pu, Lianyu Lin, Qian Deng, Yuhan Li, Weiyun Wang, Yan Jin, Zhensheng Hu, Ziyu Zhou, Guo Chen, Liling Jiang, Hao Wang, Xiaoyang Zhao, Xiangwei He, Junfen Fu, Holger A. Russ, Wei Li & Saiyong Zhu, 2023 Harnessing endogenous transcription factors directly by small molecules for chemically induced pluripotency inception, Yan Jin#, Yunkun Lu# , Lianyu Lin, Chao Liu, Xiaojie Ma, Xi Chen, Ziyu Zhou, Zhensheng Hu, Jiaqi Pu, Guo Chen, Qian Deng, Liling Jiang, Yuhan Li, Yulong Zhao, Hao Wang, Junfen Fu, Wei Li & Saiyong Zhu, 2023 N6-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis, Xiaojie Ma#, Jie Cao#, Ziyu Zhou#, Yunkun Lu#, Qin Li, Yan Jin, Guo Chen, Weiyun Wang, Wenyan Ge, Xi Chen, Zhensheng Hu, Xiao Shu, Qian Deng, Jiaqi Pu, Chengzhen Liang, Junfen Fu, Jianzhao Liu & Saiyong Zhu, 2022 MiR-95-3p acts as a prognostic marker and promotes cervical cancer progression by targeting VCAM1, Sijie Feng#, Yunkun Lu#, Lisha Sun#, Shuangying Hao, Zhiqiang Liu, Fangyuan Yang, Lin Zhang, Ting Wang, Lihong Jiang, Juan Zhang, Shuyan Liu, Hui Pang, Zhenhui Wang & Hong Wang, 2022 Exploring specific prognostic biomarkers in triple-negative breast cancer, Chang Bao#, Yunkun Lu#, Jishun Chen#, Danni Chen, Weiyang Lou, Bisha Ding, Liang Xu & Weimin Fan, 2019 Identification of prognostic biomarkers for cervical cancer based on programmed cell death-related genes and assessment of their immune profile and response to drug therapy, Sijie Feng, Zhenhui Wang, Huizhen Zhang, Baohua Hou, Yanjun Xu, Shuangying Hao* & Yunkun Lu, 2023 CEP20 promotes invasion and metastasis of non-small cell lung cancer cells by depolymerizing microtubules, Sijie Feng#, Shuai Yuan#, Baohua Hou, Zhiqiang Liu, Yanjun Xu, Shuangying Hao & Yunkun Lu, 2023 The phase separation of extracellular matrix protein matrilin-3 from cancer-associated fibroblasts contributes to gastric cancer invasion, Yuliang Huang#, Xiaoyang Xu#, Yunkun Lu, Qiang Sun, Lu Zhang, Jiaqi Shao, Dingwei Chen, Yongxia Chang, Xiaoxia Sun, Wei Zhuo, Tianhua Zhou, 2024 Human expandable pancreatic progenitor–derived β cells ameliorate diabetes, Xiaojie Ma, Yunkun Lu, Ziyu Zhou, Qin Li, Xi Chen, Weiyun Wang, Yan Jin, Zhengsheng Hu, Guo Chen, Qian Deng, Weina Shang, Hao Wang, HongXing Fu, Xiangwei He, Xin-hua Feng & Saiyong Zhu, 2022 Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production, Weiyun Wang, Shaofang Ren, Yunkun Lu, Xi Chen, Juanjuan Qu, Xiaojie Ma, Qian Deng, Zhensheng Hu, Yan Jin, Ziyu Zhou, Wenyan Ge, Yibing Zhu, Nannan Yang, Qin Li, Jiaqi Pu, Guo Chen, Cunqi Ye, Hao Wang, Xiaoyang Zhao, Zhiqiang Liu & Saiyong Zhu*, 2021 MiR-93 suppresses tumorigenesis and enhances chemosensitivity of breast cancer via dual targeting E2F1 and CCND

Areas of Focus

肝胆恶性肿瘤中转座元件的潜在作用机制研究
肝胆恶性肿瘤中免疫代谢微环境
恶性肿瘤中表观遗传图谱构建

Publications

N-acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling, Zhensheng Hu#, Yunkun Lu#, Jie Cao#, Lianyu Lin#, Xi Chen, Ziyu Zhou, Jiaqi Pu, Guo Chen, Xiaojie Ma, Qian Deng, Yan Jin, Liling Jiang, Yuhan Li, Tengwei Li, Jianzhao Liu* & Saiyong Zhu*, 2024
ACLS4 could be a potential therapeutic target for severe acute pancreatitis, Feng Guo#, Yunkun Lu#, Lijun Du, Xiuliu Guo, Jinyan Xie* & Xiujun Cai*, 2024
A fast chemical reprogramming system promotes cell identity transition through a diapause-like state, Xi Chen#, Yunkun Lu#, Leyun Wang, Xiaojie Ma, Jiaqi Pu, Lianyu Lin, Qian Deng, Yuhan Li, Weiyun Wang, Yan Jin, Zhensheng Hu, Ziyu Zhou, Guo Chen, Liling Jiang, Hao Wang, Xiaoyang Zhao, Xiangwei He, Junfen Fu, Holger A. Russ, Wei Li & Saiyong Zhu*, 2023
Harnessing endogenous transcription factors directly by small molecules for chemically induced pluripotency inception, Yan Jin#, Yunkun Lu# , Lianyu Lin, Chao Liu, Xiaojie Ma, Xi Chen, Ziyu Zhou, Zhensheng Hu, Jiaqi Pu, Guo Chen, Qian Deng, Liling Jiang, Yuhan Li, Yulong Zhao, Hao Wang, Junfen Fu, Wei Li & Saiyong Zhu*, 2023
N6-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis, Xiaojie Ma#, Jie Cao#, Ziyu Zhou#, Yunkun Lu#, Qin Li, Yan Jin, Guo Chen, Weiyun Wang, Wenyan Ge, Xi Chen, Zhensheng Hu, Xiao Shu, Qian Deng, Jiaqi Pu, Chengzhen Liang, Junfen Fu, Jianzhao Liu* & Saiyong Zhu*, 2022
MiR-95-3p acts as a prognostic marker and promotes cervical cancer progression by targeting VCAM1, Sijie Feng#, Yunkun Lu#, Lisha Sun#, Shuangying Hao, Zhiqiang Liu, Fangyuan Yang, Lin Zhang, Ting Wang, Lihong Jiang, Juan Zhang, Shuyan Liu, Hui Pang, Zhenhui Wang* & Hong Wang*, 2022
Exploring specific prognostic biomarkers in triple-negative breast cancer, Chang Bao#, Yunkun Lu#, Jishun Chen#, Danni Chen, Weiyang Lou, Bisha Ding, Liang Xu & Weimin Fan*, 2019
Identification of prognostic biomarkers for cervical cancer based on programmed cell death-related genes and assessment of their immune profile and response to drug therapy, Sijie Feng, Zhenhui Wang, Huizhen Zhang, Baohua Hou, Yanjun Xu, Shuangying Hao* & Yunkun Lu*, 2023
CEP20 promotes invasion and metastasis of non-small cell lung cancer cells by depolymerizing microtubules, Sijie Feng#, Shuai Yuan#, Baohua Hou, Zhiqiang Liu, Yanjun Xu, Shuangying Hao* & Yunkun Lu*, 2023
The phase separation of extracellular matrix protein matrilin-3 from cancer-associated fibroblasts contributes to gastric cancer invasion, Yuliang Huang#, Xiaoyang Xu#, Yunkun Lu, Qiang Sun, Lu Zhang, Jiaqi Shao, Dingwei Chen, Yongxia Chang, Xiaoxia Sun, Wei Zhuo*, Tianhua Zhou*, 2024
Human expandable pancreatic progenitor–derived β cells ameliorate diabetes, Xiaojie Ma, Yunkun Lu, Ziyu Zhou, Qin Li, Xi Chen, Weiyun Wang, Yan Jin, Zhengsheng Hu, Guo Chen, Qian Deng, Weina Shang, Hao Wang, HongXing Fu, Xiangwei He, Xin-hua Feng & Saiyong Zhu*, 2022
Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production, Weiyun Wang, Shaofang Ren, Yunkun Lu, Xi Chen, Juanjuan Qu, Xiaojie Ma, Qian Deng, Zhensheng Hu, Yan Jin, Ziyu Zhou, Wenyan Ge, Yibing Zhu, Nannan Yang, Qin Li, Jiaqi Pu, Guo Chen, Cunqi Ye, Hao Wang, Xiaoyang Zhao, Zhiqiang Liu & Saiyong Zhu*, 2021
MiR-93 suppresses tumorigenesis and enhances chemosensitivity of breast cancer via dual targeting E2F1 and CCND

转座元件肝胆恶性肿瘤免疫代谢微环境表观遗传学肿瘤进展生物信息学多组学细胞生物学癌症研究

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