Professor | Cheng Ma | Asia Growth Partners

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Name	Cheng Ma
Contact Information	mac4@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

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Name

Cheng Ma

Contact Information

mac4@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical
Academic Background & Achievements	2005-2009 Bachelor's Degree: Zhejiang University 2008-2009 Master's Degree: University of Leeds 2009-2013 PhD: University of Leeds Built and managed the protein platform at Zhejiang University School of Medicine Published research in high-impact journals such as Science Bulletin, Cell Reports, and Nature Granted 1 invention patent and 2 utility model patents Developed a virtual simulation teaching platform for protein purification
Work Experience	2022.12-present - Zhejiang University - Head of Protein Platform, School of Medicine 2016.12-2022.12 - Zhejiang University - Head of Protein Platform, School of Medicine 2013.07-2016.11 - Cardiff University - Postdoctoral/Assistant Researcher
Awards	Zhejiang Province Third Prize in Analytical Testing Science and Technology

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Academic Background & Achievements

2005-2009 Bachelor's Degree: Zhejiang University
2008-2009 Master's Degree: University of Leeds
2009-2013 PhD: University of Leeds
Built and managed the protein platform at Zhejiang University School of Medicine
Published research in high-impact journals such as Science Bulletin, Cell Reports, and Nature
Granted 1 invention patent and 2 utility model patents
Developed a virtual simulation teaching platform for protein purification

Work Experience

2022.12-present - Zhejiang University - Head of Protein Platform, School of Medicine
2016.12-2022.12 - Zhejiang University - Head of Protein Platform, School of Medicine
2013.07-2016.11 - Cardiff University - Postdoctoral/Assistant Researcher

Awards

Zhejiang Province Third Prize in Analytical Testing Science and Technology

Areas of Focus	Expression, purification, and characterization of membrane proteins and protein complexes Functional and structural biology of metal ion transporters and channel proteins
Publications	Evolutionary trajectory of TRPM2 channel activation by adenosine diphosphate ribose and calcium, C. Ma, Y. Luo, C. Zhang, C. Cheng, N. Hua, X. Liu, J. Wu, L. Qin, P. Yu, J. Luo, F. Yang, L-H. Jiang, G. Zhang, W. Yang, 2024 Considerations in production of the prokaryotic ZIP family transporters for structural and functional studies, Ma C, Gong C, 2024 ACE2 models of frequently contacted animals provide clues of their SARS-CoV-2 S protein affinity and viral susceptibility, Ma C, Gong C, 2021 Expression, Purification and Characterization of a ZIP Family Transporter from Desulfovibrio vulgaris, Ma C, Gong C, 2021 Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel, Yu X, Xie Y, Zhang X, Ma C, Liu L, Zhen W, Xu L, Zhang J, Liang Y, Zhao L, Gao X, Yu P, Luo J, Jiang LH, Nie Y, Yang F, Guo J, Yang W, 2021 Gastrodia elata and parishin ameliorate aging induced 'leaky gut' in mice: correlation with gut microbiota, Gong CX, Ma C, Irge DD, Li SM, Chen SM, Zhou SX, Zhao XX, Li HY, Li JY, Yang YM, Xiang L, Zhang Q, 2023 TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly, Yao W., Chen Y., Chen Y., Zhao P., Liu J., Zhang Y., Jiang Q., Wu C., Xie Y., Fan S., Ye M., Wang Y., Feng Y., Bai X., Fan M., Feng S., Wang J., Cui Y., Xia H., Ma C., Xie Z., Zhang L., Sun Q., Liu W. & Yi C., 2023 Structural basis of GPBAR activation and bile acid recognition, Yang F, Mao C, Guo L, Lin J, Ming Q, Xiao P, Wu X, Shen Q, Guo S, Shen DD, Lu R, Zhang L, Huang S, Ping Y, Zhang C, Ma C, Zhang K, Liang X, Shen Y, Nan F, Yi F, Luca VC, Zhou J, Jiang C, Sun JP, Xie X, Yu X, Zhang Y, 2020 Structural basis for activation of the growth hormone-releasing hormone receptor, Zhou F, Zhang H, Cong Z, Zhao LH, Zhou Q, Mao C, Cheng X, Shen DD, Cai X, Ma C, Wang Y, Dai A, Zhou Y, Sun W, Zhao F, Zhao S, Jiang H, Jiang Y, Yang D, Eric Xu H, Zhang Y, Wang MW, 2020 Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel, Xu L, Han Y, Chen X, Aierken A, Wen H, Zheng W, Wang H, Lu X, Zhao Z, Ma C, Liang P, Yang W, Yang S, Yang F, 2020 De Novo Design of Peptidic Positive Allosteric Modulators Targeting TRPV1 with Analgesic Effects, Xu L, Zhang H, Wang Y, Lu X, Zhao Z, Ma C, Yang S, Yarov-Yarovoy V, Tian Y, Zheng J, Yang F, 2021 Effects of calcium-binding sites in the S2-S3 loop on human and Nematostella vectensis TRPM2 channel gating processes, Luo YH, Yu XF, Ma C, Yang F, Yang W, 2019

Areas of Focus

Expression, purification, and characterization of membrane proteins and protein complexes
Functional and structural biology of metal ion transporters and channel proteins

Publications

Evolutionary trajectory of TRPM2 channel activation by adenosine diphosphate ribose and calcium, C. Ma, Y. Luo, C. Zhang, C. Cheng, N. Hua, X. Liu, J. Wu, L. Qin, P. Yu, J. Luo, F. Yang, L-H. Jiang, G. Zhang, W. Yang, 2024
Considerations in production of the prokaryotic ZIP family transporters for structural and functional studies, Ma C, Gong C, 2024
ACE2 models of frequently contacted animals provide clues of their SARS-CoV-2 S protein affinity and viral susceptibility, Ma C, Gong C, 2021
Expression, Purification and Characterization of a ZIP Family Transporter from Desulfovibrio vulgaris, Ma C, Gong C, 2021
Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel, Yu X, Xie Y, Zhang X, Ma C, Liu L, Zhen W, Xu L, Zhang J, Liang Y, Zhao L, Gao X, Yu P, Luo J, Jiang LH, Nie Y, Yang F, Guo J, Yang W, 2021
Gastrodia elata and parishin ameliorate aging induced 'leaky gut' in mice: correlation with gut microbiota, Gong CX, Ma C, Irge DD, Li SM, Chen SM, Zhou SX, Zhao XX, Li HY, Li JY, Yang YM, Xiang L, Zhang Q, 2023
TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly, Yao W., Chen Y., Chen Y., Zhao P., Liu J., Zhang Y., Jiang Q., Wu C., Xie Y., Fan S., Ye M., Wang Y., Feng Y., Bai X., Fan M., Feng S., Wang J., Cui Y., Xia H., Ma C., Xie Z., Zhang L., Sun Q., Liu W. & Yi C., 2023
Structural basis of GPBAR activation and bile acid recognition, Yang F, Mao C, Guo L, Lin J, Ming Q, Xiao P, Wu X, Shen Q, Guo S, Shen DD, Lu R, Zhang L, Huang S, Ping Y, Zhang C, Ma C, Zhang K, Liang X, Shen Y, Nan F, Yi F, Luca VC, Zhou J, Jiang C, Sun JP, Xie X, Yu X, Zhang Y, 2020
Structural basis for activation of the growth hormone-releasing hormone receptor, Zhou F, Zhang H, Cong Z, Zhao LH, Zhou Q, Mao C, Cheng X, Shen DD, Cai X, Ma C, Wang Y, Dai A, Zhou Y, Sun W, Zhao F, Zhao S, Jiang H, Jiang Y, Yang D, Eric Xu H, Zhang Y, Wang MW, 2020
Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel, Xu L, Han Y, Chen X, Aierken A, Wen H, Zheng W, Wang H, Lu X, Zhao Z, Ma C, Liang P, Yang W, Yang S, Yang F, 2020
De Novo Design of Peptidic Positive Allosteric Modulators Targeting TRPV1 with Analgesic Effects, Xu L, Zhang H, Wang Y, Lu X, Zhao Z, Ma C, Yang S, Yarov-Yarovoy V, Tian Y, Zheng J, Yang F, 2021
Effects of calcium-binding sites in the S2-S3 loop on human and Nematostella vectensis TRPM2 channel gating processes, Luo YH, Yu XF, Ma C, Yang F, Yang W, 2019

Membrane Proteins Protein Complexes Expression Purification Characterization Metal Ion Transporters Channel Proteins Functional Biology Structural Biology Biochemistry

Xiaohui Cang - Zhejiang University

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