Professor | Hua Cai | Asia Growth Partners

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Name	Hua Cai
Contact Information	chjorbe@hotmail.com
Language ability	Chinese, English
Province	Guangdong

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Name

Hua Cai

Contact Information

chjorbe@hotmail.com

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Guangzhou Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	PhD: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
Awards	Guangzhou High-Level Talent - Outstanding Expert First Guangdong Association for Science and Technology Young Talent Returned Overseas Scholar

University/Lab Affiliation and Title

Guangzhou Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

PhD: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

Awards

Guangzhou High-Level Talent - Outstanding Expert
First Guangdong Association for Science and Technology Young Talent
Returned Overseas Scholar

Areas of Focus	Study of antiviral innate immunity induced by the interaction of viral components with pattern recognition receptors using Drosophila and mammals as models
Publications	Two cGAS-like receptors induce Sting-dependent antiviral immunity in Drosophila melanogaster, Andreas Holleufer, Kasper Grønbjerg Winther, Hans Henrik Gad, Xianlong Ai, Yuqiang Chen, Lihua Li, Ziming Wei, Huimin Deng, Jiyong Liu, Ninna Ahlmann Frederiksen, Bine Simonsen, Line Lykke Andersen, Karin Kleigrewe, Louise Dalskov, Andreas Pichlmair, Hua Cai, Jean-Luc Imler, Rune Hartmann, 2021 cGAS-like receptors control RNA sensing and 3’2’-cGAMP antiviral signaling in Drosophila, Slavik KM, Morehouse BR, Ragucci AE, Zhou W, Ai X, Chen Y, Li L, Wei Z, Bähre H, König M, Seifert R, Cai H, Imler JL, Kranzusch P, 2021 2'3'-cGAMP triggers a STING- and NF-kappaB-dependent broad antiviral response in Drosophila, Cai, H., Holleufer, A., Simonsen, B., Schneider, J., Lemoine, A., Gad, H. H., Huang, J., Huang, J., Chen, D., Peng, T., Marques, J. T., Hartmann, R., Martins, N. E., and Imler, J. L., 2020 cGAS-STING: insight on the evolution of a primordial antiviral signaling cassette, Hua Cai, Jean-Luc Imler, 2021 cGAS-like receptor-mediated immunity: the insect perspective, Hua Cai, Carine Meignin & Jean-Luc Imler, 2022 The Kinase IKKbeta Regulates a STING- and NF-kappaB-Dependent Antiviral Response Pathway in Drosophila, Goto, A., Okado, K., Martins, N., Cai, H., Barbier, V., Lamiable, O., Troxler, L., Santiago, E., Kuhn, L., Paik, D., Silverman, N., Holleufer, A., Hartmann, R., Liu, J., Peng, T., Hoffmann, J. A., Meignin, C., Daeffler, L., and Imler, J. L., 2018 The cellular and viral circRNAome induced by respiratory syncytial virus infection, Wenxia Yao, Jinghui Pan, Zhaoyu Liu, Zhijie Dong, Min Liang, Shu Xia, Yao Xiao, Xiaodan Cai, Tao Peng, Xinke Zhou, Hua Cai, 2021 Apolipoprotein M, identified as a novel hepatitis C virus (HCV) particle associated protein, contributes to HCV assembly and interacts with E2 protein, Cai, H., Yao, W., Huang, J., Xiao, J., Chen, W., Hu, L., Mai, R., Liang, M., Chen, D., Jiang, N., Zhou, L., Peng, T., 2020 Cell-death-inducing DFFA-like Effector B Contributes to the Assembly of Hepatitis C Virus (HCV) Particles and Interacts with HCV NS5A, Cai, H., Yao, W., Li, L., Li, X., Hu, L., Mai, R., and Peng, T, 2016 Endoplasmic Reticulum Stress Links Hepatitis C Virus RNA Replication to Wild-Type PGC-1alpha/Liver-Specific PGC-1alpha Upregulation, Wenxia Yao, Hua Cai, Xinlei Li, Ting Li, Longbo Hu, Tao Peng, 2014

Areas of Focus

Study of antiviral innate immunity induced by the interaction of viral components with pattern recognition receptors using Drosophila and mammals as models

Publications

Two cGAS-like receptors induce Sting-dependent antiviral immunity in Drosophila melanogaster, Andreas Holleufer, Kasper Grønbjerg Winther, Hans Henrik Gad, Xianlong Ai, Yuqiang Chen, Lihua Li, Ziming Wei, Huimin Deng, Jiyong Liu, Ninna Ahlmann Frederiksen, Bine Simonsen, Line Lykke Andersen, Karin Kleigrewe, Louise Dalskov, Andreas Pichlmair, Hua Cai, Jean-Luc Imler, Rune Hartmann, 2021
cGAS-like receptors control RNA sensing and 3’2’-cGAMP antiviral signaling in Drosophila, Slavik KM, Morehouse BR, Ragucci AE, Zhou W, Ai X, Chen Y, Li L, Wei Z, Bähre H, König M, Seifert R, Cai H, Imler JL, Kranzusch P, 2021
2'3'-cGAMP triggers a STING- and NF-kappaB-dependent broad antiviral response in Drosophila, Cai, H., Holleufer, A., Simonsen, B., Schneider, J., Lemoine, A., Gad, H. H., Huang, J., Huang, J., Chen, D., Peng, T., Marques, J. T., Hartmann, R., Martins, N. E., and Imler, J. L., 2020
cGAS-STING: insight on the evolution of a primordial antiviral signaling cassette, Hua Cai, Jean-Luc Imler, 2021
cGAS-like receptor-mediated immunity: the insect perspective, Hua Cai, Carine Meignin & Jean-Luc Imler, 2022
The Kinase IKKbeta Regulates a STING- and NF-kappaB-Dependent Antiviral Response Pathway in Drosophila, Goto, A., Okado, K., Martins, N., Cai, H., Barbier, V., Lamiable, O., Troxler, L., Santiago, E., Kuhn, L., Paik, D., Silverman, N., Holleufer, A., Hartmann, R., Liu, J., Peng, T., Hoffmann, J. A., Meignin, C., Daeffler, L., and Imler, J. L., 2018
The cellular and viral circRNAome induced by respiratory syncytial virus infection, Wenxia Yao, Jinghui Pan, Zhaoyu Liu, Zhijie Dong, Min Liang, Shu Xia, Yao Xiao, Xiaodan Cai, Tao Peng, Xinke Zhou, Hua Cai, 2021
Apolipoprotein M, identified as a novel hepatitis C virus (HCV) particle associated protein, contributes to HCV assembly and interacts with E2 protein, Cai, H., Yao, W., Huang, J., Xiao, J., Chen, W., Hu, L., Mai, R., Liang, M., Chen, D., Jiang, N., Zhou, L., Peng, T., 2020
Cell-death-inducing DFFA-like Effector B Contributes to the Assembly of Hepatitis C Virus (HCV) Particles and Interacts with HCV NS5A, Cai, H., Yao, W., Li, L., Li, X., Hu, L., Mai, R., and Peng, T, 2016
Endoplasmic Reticulum Stress Links Hepatitis C Virus RNA Replication to Wild-Type PGC-1alpha/Liver-Specific PGC-1alpha Upregulation, Wenxia Yao, Hua Cai, Xinlei Li, Ting Li, Longbo Hu, Tao Peng, 2014

Antiviral Innate Immunity Drosophila Mammals Viral Components Pattern Recognition Receptors Evolution Immune Response Model Organisms Research

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