Professor | 蔡华 | 数字化转型顾问

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Name	蔡华
Contact Information	chjorbe@hotmail.com
Language ability	中文, 英文
Province	广东

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Name

蔡华

Contact Information

chjorbe@hotmail.com

Language ability

中文, 英文

Province

广东

University/Lab Affiliation and Title	广州医科大学
Faculty	Basic Medical Sciences
Academic Background & Achievements	博士: 中科院广州生物医药与健康研究院
Awards	广州市高层次人才——优秀专家首届广东省科学技术协会青年培育人才海外归国留学人员

University/Lab Affiliation and Title

广州医科大学

Faculty

Basic Medical Sciences

Academic Background & Achievements

博士: 中科院广州生物医药与健康研究院

Awards

广州市高层次人才——优秀专家
首届广东省科学技术协会青年培育人才
海外归国留学人员

Areas of Focus	利用果蝇和哺乳动物为模型，研究病毒组分与模式识别受体结合诱导的抗病毒天然免疫及其进化
Publications	Two cGAS-like receptors induce Sting-dependent antiviral immunity in Drosophila melanogaster, Andreas Holleufer, Kasper Grønbjerg Winther, Hans Henrik Gad, Xianlong Ai, Yuqiang Chen, Lihua Li, Ziming Wei, Huimin Deng, Jiyong Liu, Ninna Ahlmann Frederiksen, Bine Simonsen, Line Lykke Andersen, Karin Kleigrewe, Louise Dalskov, Andreas Pichlmair, Hua Cai, Jean-Luc Imler, Rune Hartmann, 2021 cGAS-like receptors control RNA sensing and 3’2’-cGAMP antiviral signaling in Drosophila, Slavik KM, Morehouse BR, Ragucci AE, Zhou W, Ai X, Chen Y, Li L, Wei Z, Bähre H, König M, Seifert R, Cai H, Imler JL, Kranzusch P, 2021 2'3'-cGAMP triggers a STING- and NF-kappaB-dependent broad antiviral response in Drosophila, Cai, H., Holleufer, A., Simonsen, B., Schneider, J., Lemoine, A., Gad, H. H., Huang, J., Huang, J., Chen, D., Peng, T., Marques, J. T., Hartmann, R., Martins, N. E., and Imler, J. L., 2020 cGAS-STING: insight on the evolution of a primordial antiviral signaling cassette, Hua Cai, Jean-Luc Imler, 2021 cGAS-like receptor-mediated immunity: the insect perspective, Hua Cai, Carine Meignin & Jean-Luc Imler, 2022 The Kinase IKKbeta Regulates a STING- and NF-kappaB-Dependent Antiviral Response Pathway in Drosophila, Goto, A., Okado, K., Martins, N., Cai, H., Barbier, V., Lamiable, O., Troxler, L., Santiago, E., Kuhn, L., Paik, D., Silverman, N., Holleufer, A., Hartmann, R., Liu, J., Peng, T., Hoffmann, J. A., Meignin, C., Daeffler, L., and Imler, J. L., 2018 The cellular and viral circRNAome induced by respiratory syncytial virus infection, Wenxia Yao, Jinghui Pan, Zhaoyu Liu, Zhijie Dong, Min Liang, Shu Xia, Yao Xiao, Xiaodan Cai, Tao Peng, Xinke Zhou, Hua Cai, 2021 Apolipoprotein M, identified as a novel hepatitis C virus (HCV) particle associated protein, contributes to HCV assembly and interacts with E2 protein, Cai, H., Yao, W., Huang, J., Xiao, J., Chen, W., Hu, L., Mai, R., Liang, M., Chen, D., Jiang, N., Zhou, L., Peng, T., 2020 Cell-death-inducing DFFA-like Effector B Contributes to the Assembly of Hepatitis C Virus (HCV) Particles and Interacts with HCV NS5A, Cai, H., Yao, W., Li, L., Li, X., Hu, L., Mai, R., and Peng, T, 2016 Endoplasmic Reticulum Stress Links Hepatitis C Virus RNA Replication to Wild-Type PGC-1alpha/Liver-Specific PGC-1alpha Upregulation, Wenxia Yao, Hua Cai, Xinlei Li, Ting Li, Longbo Hu, Tao Peng, 2014

Areas of Focus

利用果蝇和哺乳动物为模型，研究病毒组分与模式识别受体结合诱导的抗病毒天然免疫及其进化

Publications

Two cGAS-like receptors induce Sting-dependent antiviral immunity in Drosophila melanogaster, Andreas Holleufer, Kasper Grønbjerg Winther, Hans Henrik Gad, Xianlong Ai, Yuqiang Chen, Lihua Li, Ziming Wei, Huimin Deng, Jiyong Liu, Ninna Ahlmann Frederiksen, Bine Simonsen, Line Lykke Andersen, Karin Kleigrewe, Louise Dalskov, Andreas Pichlmair, Hua Cai, Jean-Luc Imler, Rune Hartmann, 2021
cGAS-like receptors control RNA sensing and 3’2’-cGAMP antiviral signaling in Drosophila, Slavik KM, Morehouse BR, Ragucci AE, Zhou W, Ai X, Chen Y, Li L, Wei Z, Bähre H, König M, Seifert R, Cai H, Imler JL, Kranzusch P, 2021
2'3'-cGAMP triggers a STING- and NF-kappaB-dependent broad antiviral response in Drosophila, Cai, H., Holleufer, A., Simonsen, B., Schneider, J., Lemoine, A., Gad, H. H., Huang, J., Huang, J., Chen, D., Peng, T., Marques, J. T., Hartmann, R., Martins, N. E., and Imler, J. L., 2020
cGAS-STING: insight on the evolution of a primordial antiviral signaling cassette, Hua Cai, Jean-Luc Imler, 2021
cGAS-like receptor-mediated immunity: the insect perspective, Hua Cai, Carine Meignin & Jean-Luc Imler, 2022
The Kinase IKKbeta Regulates a STING- and NF-kappaB-Dependent Antiviral Response Pathway in Drosophila, Goto, A., Okado, K., Martins, N., Cai, H., Barbier, V., Lamiable, O., Troxler, L., Santiago, E., Kuhn, L., Paik, D., Silverman, N., Holleufer, A., Hartmann, R., Liu, J., Peng, T., Hoffmann, J. A., Meignin, C., Daeffler, L., and Imler, J. L., 2018
The cellular and viral circRNAome induced by respiratory syncytial virus infection, Wenxia Yao, Jinghui Pan, Zhaoyu Liu, Zhijie Dong, Min Liang, Shu Xia, Yao Xiao, Xiaodan Cai, Tao Peng, Xinke Zhou, Hua Cai, 2021
Apolipoprotein M, identified as a novel hepatitis C virus (HCV) particle associated protein, contributes to HCV assembly and interacts with E2 protein, Cai, H., Yao, W., Huang, J., Xiao, J., Chen, W., Hu, L., Mai, R., Liang, M., Chen, D., Jiang, N., Zhou, L., Peng, T., 2020
Cell-death-inducing DFFA-like Effector B Contributes to the Assembly of Hepatitis C Virus (HCV) Particles and Interacts with HCV NS5A, Cai, H., Yao, W., Li, L., Li, X., Hu, L., Mai, R., and Peng, T, 2016
Endoplasmic Reticulum Stress Links Hepatitis C Virus RNA Replication to Wild-Type PGC-1alpha/Liver-Specific PGC-1alpha Upregulation, Wenxia Yao, Hua Cai, Xinlei Li, Ting Li, Longbo Hu, Tao Peng, 2014

抗病毒天然免疫果蝇哺乳动物病毒组分模式识别受体进化免疫反应模型生物研究

夏朋延 - 北京大学

谈新提 - 武汉大学

Area of Focus
肿瘤 | 免疫学 | 癌症 | 细胞 | 分子 | 治疗 | 免疫反应 | 肿瘤学 | 研究 | 临床试验

黎明 - 中南大学

Area of Focus
肿瘤 | 免疫学 | 癌症 | 细胞 | 治疗 | 免疫反应 | 分子 | 研究 | 临床试验 | 生物标志物

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