Professor | Yi Fan | Asia Growth Partners

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Name	Yi Fan
Contact Information	yfan@njmu.edu.cn
Language ability	Chinese, English
Province	Jiangsu

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Name

Yi Fan

Contact Information

yfan@njmu.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2002-2007 PhD in Pharmacology: Nanjing Medical University 1997-2002 Bachelor's in Clinical Medicine: Nanjing Medical University
Work Experience	2021-10 to Present - Nanjing Medical University - Professor, Department of Pharmacology 2011-11 to 2013-08 - Medical College of Georgia - Visiting Scholar 2011-01 to 2021-09 - Nanjing Medical University - Associate Professor, Department of Pharmacology 2007-09 to 2011-01 - Nanjing Medical University - Lecturer, Department of Pharmacology

University/Lab Affiliation and Title

Nanjing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2002-2007 PhD in Pharmacology: Nanjing Medical University
1997-2002 Bachelor's in Clinical Medicine: Nanjing Medical University

Work Experience

2021-10 to Present - Nanjing Medical University - Professor, Department of Pharmacology
2011-11 to 2013-08 - Medical College of Georgia - Visiting Scholar
2011-01 to 2021-09 - Nanjing Medical University - Associate Professor, Department of Pharmacology
2007-09 to 2011-01 - Nanjing Medical University - Lecturer, Department of Pharmacology

Areas of Focus	Neuropharmacology
Publications	Stimulation of Α7-NAChRs Coordinates Autophagy and Apoptosis Signaling in Experimental Knee Osteoarthritis., Liu Y, Xu S, Zhang H, Qian K, Huang J, Gu X, Li Y, Fan Y, Hu J., 2021 Activation of α7-nAChRs promotes the clearance of α-Synuclein and protects against apoptotic cell death induced by exogenous α-Synuclein fibrils., Zhao JF, Li Y, Li Y, Xu S, Tao TT, Hua Y, Zhang J, Fan Y., 2021 Minocycline promotes functional recovery in ischemic stroke by modulating microglia polarization through STAT1/STAT6 pathways., Lu YN, Zhou MM, Li Y, Li Y, Hua Y, Fan Y., 2021 Activation of α7 nicotinic acetylcholine receptor protects against 1-methyl-4-phenylpyridinium-induced astroglial apoptosis., Hua Y, Yang BB, Chen Q, Zhang J, Hu J, Fan Y., 2019 Enhancing the astrocytic clearance of extracellular a-synuclein aggregates by Ginkgolides attenuates neural cell injury., Hua J, Yin N, Xu S, Chen Q, Tao TT, Zhang J, Ding JH, Fan Y, Hu G., 2019 Activation of α7-nAChRs protects SH-SY5Y cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death via ERK/p53 signaling pathway., Xu S, Yang B, Tao T, Zhang J, Liu Y, Hu J, Fan Y, Zhang G., 2019 Ginkgolide B and bilobalide ameliorate neural cell apoptosis in α-synuclein aggregates., Hua J, Yin N, Yang B, Zhang J, Ding JH, Fan Y, Hu G., 2017 GPER Agonist G1 Attenuates neuroinflammation and dopaminergic neurodegeneration in Parkinson disease., Guan J, Yang BB, Fan Y, Zhang J., 2017 Aquaporin-4 mediates the suppressive effect of lipopolysaccharide on hippocampal neurogenesis., Liang R, Yong S, Huang X, Kong H, Hu G, Fan Y., 2016 Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson‘s disease., Sun HB, Liang R, Yang BB, Zhou Y, Liu MD, Fang F, Ding JH, Fan Y, Hu G., 2016 Aquaporin-4 deficiency diminishes the differential degeneration of midbrain dopaminergic neurons in experimental Parkinson ‘s disease., Zhang J, Yang BB, Sun HB, Zhou Y, Liu MD, Ding JH, Fang F, Fan Y, Hu G., 2016 ATP-sensitive potassium channels: uncovering novel targets for treating depression., Fan Y, Kong H, Ye XH, Ding JH, and Hu G., 2016 Glia Protein Aquaporin-4 Regulates Aversive Motivation of Spatial Memory in Morris Water Maze., Zhang J, Li Y, Chen ZG, Dang H, Ding JH, Fan Y, Hu G., 2013 Aquaporin-4 promotes memory consolidation in Morris water maze., Fan Y, Liu M, Wu X, Wang F, Ding J, Chen J, Hu G., 2013 A single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of alpha2A-adrenergic receptor., Fan Y, Li C, Guo J, Hu G, Wu G., 2012 Novel role of aquaporin-4 in CD4+ CD25+ T regulatory cell development and severity of Parkinson's disease., Chi Y#, Fan Y#, He L, Liu W, Wen X, Zhou S, Wang X, Zhang C, Kong H, Sonoda L, Tripathi P, Li CJ, Yu MS, Su C, Hu G., 2011 Hypersensitivity of Aquaporin 4-Deficient Mice to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyrindine and Astrocytic Modulation., Fan Y, Kong H, Shi X, Sun X, Ding J, Wu J, Hu G., 2008 Sex- and Region-Specific Alterations of Basal Amino Acid and Monoamine Metabolism in the Brain of Aquaporin-4 Knockout Mice., Fan Y, Zhang J, Sun XL, Gao L, Zeng XN, Ding JH, Cao C, Niu L, Hu G., 2005 Alterations of Striatal Neurotransmitter Release in Aquaporin-4 Deficient Mice: An in Vivo Microdialysis Study., Ding JH, Sha LL, Chang J, Zhou XQ, Fan Y*, Hu G., 2007

Areas of Focus

Neuropharmacology

Publications

Stimulation of Α7-NAChRs Coordinates Autophagy and Apoptosis Signaling in Experimental Knee Osteoarthritis., Liu Y, Xu S, Zhang H, Qian K, Huang J, Gu X, Li Y, Fan Y*, Hu J*., 2021
Activation of α7-nAChRs promotes the clearance of α-Synuclein and protects against apoptotic cell death induced by exogenous α-Synuclein fibrils., Zhao JF, Li Y, Li Y, Xu S, Tao TT, Hua Y, Zhang J*, Fan Y*., 2021
Minocycline promotes functional recovery in ischemic stroke by modulating microglia polarization through STAT1/STAT6 pathways., Lu YN, Zhou MM, Li Y, Li Y, Hua Y*, Fan Y*., 2021
Activation of α7 nicotinic acetylcholine receptor protects against 1-methyl-4-phenylpyridinium-induced astroglial apoptosis., Hua Y, Yang BB, Chen Q, Zhang J, Hu J, Fan Y*., 2019
Enhancing the astrocytic clearance of extracellular a-synuclein aggregates by Ginkgolides attenuates neural cell injury., Hua J, Yin N, Xu S, Chen Q, Tao TT, Zhang J, Ding JH, Fan Y*, Hu G*., 2019
Activation of α7-nAChRs protects SH-SY5Y cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death via ERK/p53 signaling pathway., Xu S, Yang B, Tao T, Zhang J, Liu Y, Hu J, Fan Y*, Zhang G*., 2019
Ginkgolide B and bilobalide ameliorate neural cell apoptosis in α-synuclein aggregates., Hua J, Yin N, Yang B, Zhang J, Ding JH, Fan Y*, Hu G*., 2017
GPER Agonist G1 Attenuates neuroinflammation and dopaminergic neurodegeneration in Parkinson disease., Guan J, Yang BB, Fan Y*, Zhang J*., 2017
Aquaporin-4 mediates the suppressive effect of lipopolysaccharide on hippocampal neurogenesis., Liang R, Yong S, Huang X, Kong H, Hu G, Fan Y*., 2016
Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson‘s disease., Sun HB, Liang R, Yang BB, Zhou Y, Liu MD, Fang F, Ding JH, Fan Y*, Hu G*., 2016
Aquaporin-4 deficiency diminishes the differential degeneration of midbrain dopaminergic neurons in experimental Parkinson ‘s disease., Zhang J, Yang BB, Sun HB, Zhou Y, Liu MD, Ding JH, Fang F, Fan Y*, Hu G., 2016
ATP-sensitive potassium channels: uncovering novel targets for treating depression., Fan Y, Kong H, Ye XH, Ding JH, and Hu G*., 2016
Glia Protein Aquaporin-4 Regulates Aversive Motivation of Spatial Memory in Morris Water Maze., Zhang J, Li Y, Chen ZG, Dang H, Ding JH, Fan Y*, Hu G., 2013
Aquaporin-4 promotes memory consolidation in Morris water maze., Fan Y, Liu M, Wu X, Wang F, Ding J, Chen J, Hu G*., 2013
A single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of alpha2A-adrenergic receptor., Fan Y, Li C, Guo J, Hu G, Wu G*., 2012
Novel role of aquaporin-4 in CD4+ CD25+ T regulatory cell development and severity of Parkinson's disease., Chi Y#, Fan Y#, He L, Liu W, Wen X, Zhou S, Wang X, Zhang C, Kong H, Sonoda L, Tripathi P, Li CJ, Yu MS, Su C*, Hu G., 2011
Hypersensitivity of Aquaporin 4-Deficient Mice to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyrindine and Astrocytic Modulation., Fan Y, Kong H, Shi X, Sun X, Ding J, Wu J, Hu G*., 2008
Sex- and Region-Specific Alterations of Basal Amino Acid and Monoamine Metabolism in the Brain of Aquaporin-4 Knockout Mice., Fan Y, Zhang J, Sun XL, Gao L, Zeng XN, Ding JH, Cao C, Niu L, Hu G*., 2005
Alterations of Striatal Neurotransmitter Release in Aquaporin-4 Deficient Mice: An in Vivo Microdialysis Study., Ding JH, Sha LL, Chang J, Zhou XQ, Fan Y*, Hu G., 2007

Neuropharmacology Neuropsychiatric Disorders Pathological Mechanisms Drug Therapy Glial Cells Parkinson'S Disease Depression Stroke Neuroprotection Α7-Nicotinic Acetylcholine Receptor

Wenbing Chen - Guangzhou Medical University

Xiu-Lan Sun - Nanjing Medical University

Ming Lu - Nanjing Medical University

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