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范益
Basic Medical Sciences
南京医科大学
江苏
Language: 中文, 英文
神经药理学
神经精神疾病
病理机制
药物治疗
胶质细胞
帕金森病
抑郁症
脑卒中
神经保护
Α7烟碱型乙酰胆碱受体
Areas of Focus
- 神经药理学
Work Experience
- 2021年10月至今 - 南京医科大学 - 教授，药理学系
- 2011年11月至2013年08月 - 美国乔治亚医学院 - 访问学者
- 2011年01月至2021年09月 - 南京医科大学 - 副教授，药理学系
- 2007年09月至2011年01月 - 南京医科大学 - 讲师，药理学系
Academic Background & Achievements
- 2002-2007 博士，药理学：南京医科大学
- 1997-2002 学士，临床医学：南京医科大学
Publications
- Stimulation of Α7-NAChRs Coordinates Autophagy and Apoptosis Signaling in Experimental Knee Osteoarthritis., Liu Y, Xu S, Zhang H, Qian K, Huang J, Gu X, Li Y, Fan Y*, Hu J*., 2021
- Activation of α7-nAChRs promotes the clearance of α-Synuclein and protects against apoptotic cell death induced by exogenous α-Synuclein fibrils., Zhao JF, Li Y, Li Y, Xu S, Tao TT, Hua Y, Zhang J*, Fan Y*., 2021
- Minocycline promotes functional recovery in ischemic stroke by modulating microglia polarization through STAT1/STAT6 pathways., Lu YN, Zhou MM, Li Y, Li Y, Hua Y*, Fan Y*., 2021
- Activation of α7 nicotinic acetylcholine receptor protects against 1-methyl-4-phenylpyridinium-induced astroglial apoptosis., Hua Y, Yang BB, Chen Q, Zhang J, Hu J, Fan Y*., 2019
- Enhancing the astrocytic clearance of extracellular a-synuclein aggregates by Ginkgolides attenuates neural cell injury., Hua J, Yin N, Xu S, Chen Q, Tao TT, Zhang J, Ding JH, Fan Y*, Hu G*., 2019
- Activation of α7-nAChRs protects SH-SY5Y cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death via ERK/p53 signaling pathway., Xu S, Yang B, Tao T, Zhang J, Liu Y, Hu J, Fan Y*, Zhang G*., 2019
- Ginkgolide B and bilobalide ameliorate neural cell apoptosis in α-synuclein aggregates., Hua J, Yin N, Yang B, Zhang J, Ding JH, Fan Y*, Hu G*., 2017
- GPER Agonist G1 Attenuates neuroinflammation and dopaminergic neurodegeneration in Parkinson disease., Guan J, Yang BB, Fan Y*, Zhang J*., 2017
- Aquaporin-4 mediates the suppressive effect of lipopolysaccharide on hippocampal neurogenesis., Liang R, Yong S, Huang X, Kong H, Hu G, Fan Y*., 2016
- Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson‘s disease., Sun HB, Liang R, Yang BB, Zhou Y, Liu MD, Fang F, Ding JH, Fan Y*, Hu G*., 2016
- Aquaporin-4 deficiency diminishes the differential degeneration of midbrain dopaminergic neurons in experimental Parkinson ‘s disease., Zhang J, Yang BB, Sun HB, Zhou Y, Liu MD, Ding JH, Fang F, Fan Y*, Hu G., 2016
- ATP-sensitive potassium channels: uncovering novel targets for treating depression., Fan Y, Kong H, Ye XH, Ding JH, and Hu G*., 2016
- Glia Protein Aquaporin-4 Regulates Aversive Motivation of Spatial Memory in Morris Water Maze., Zhang J, Li Y, Chen ZG, Dang H, Ding JH, Fan Y*, Hu G., 2013
- Aquaporin-4 promotes memory consolidation in Morris water maze., Fan Y, Liu M, Wu X, Wang F, Ding J, Chen J, Hu G*., 2013
- A single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of alpha2A-adrenergic receptor., Fan Y, Li C, Guo J, Hu G, Wu G*., 2012
- Novel role of aquaporin-4 in CD4+ CD25+ T regulatory cell development and severity of Parkinson's disease., Chi Y#, Fan Y#, He L, Liu W, Wen X, Zhou S, Wang X, Zhang C, Kong H, Sonoda L, Tripathi P, Li CJ, Yu MS, Su C*, Hu G., 2011
- Hypersensitivity of Aquaporin 4-Deficient Mice to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyrindine and Astrocytic Modulation., Fan Y, Kong H, Shi X, Sun X, Ding J, Wu J, Hu G*., 2008
- Sex- and Region-Specific Alterations of Basal Amino Acid and Monoamine Metabolism in the Brain of Aquaporin-4 Knockout Mice., Fan Y, Zhang J, Sun XL, Gao L, Zeng XN, Ding JH, Cao C, Niu L, Hu G*., 2005
- Alterations of Striatal Neurotransmitter Release in Aquaporin-4 Deficient Mice: An in Vivo Microdialysis Study., Ding JH, Sha LL, Chang J, Zhou XQ, Fan Y*, Hu G., 2007
