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杜仁红
Basic Medical Sciences
南京医科大学
江苏
Language: 中文, 英语
神经退行性疾病
发病机制
药物靶点
神经药理学
帕金森病
小胶质细胞
星形胶质细胞
炎症
线粒体自噬
Nlrp3炎症小体
Areas of Focus
- 神经退行性疾病的发病机制与药物靶点研究
Work Experience
- 2010-2018 - 南京医科大学 - 药理学讲师
- 2018-至今 - 南京医科大学 - 药理学副教授
Academic Background & Achievements
- 1998-2003 临床医学: 皖南医学院
- 2005-2010 药理学博士: 中山大学
- 以第一作者/通讯作者发表16篇SCI论文，累计影响因子达80
Publications
- Astragaloside IV inhibits astrocyte senescence: implication in Parkinson's disease, Xia ML, Xie XH, Ding JH, Du RH*, Hu G*, 2020
- Kir6.1/K-ATP channel on astrocytes protects against dopaminergic neurodegeneration in the MPTP mouse model of Parkinson's disease via promoting mitophagy, Hu ZL, Sun T, Lu M, Ding JH, Du RH*, Hu G*, 2019
- Astrocyte-specific deletion of Kir6.1/K-ATP channel aggravates cerebral ischemia/reperfusion injury through endoplasmic reticulum stress in mice, Zhong CJ, Chen MM, Lu M, Ding JH, Du RH*, Hu G*, 2019
- The pore-forming subunit Kir6.1 of the K-ATP channel negatively regulates the NLRP3 inflammasome to control insulin resistance by interacting with NLRP3, Du RH, Lu M, Wang C, Ding JH, Wu G, Hu G*, 2019
- Kir6.1/K-ATP channel modulates microglia phenotypes: implication in Parkinson's disease, Du RH, Sun HB, Hu ZL, Lu M, Ding JH, Hu G*, 2018
- α-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering β-arrestin2-TAB1 interaction in astrocytes, Du RH#, Zhou Y#, Xia ML, Lu M, Ding JH, Hu G, 2018
- MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease, Zhou Y#, Lu M#, Du RH#, Qiao C, Jiang CY, Zhang KZ, Ding JH, and Hu G*, 2016
- Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression, Du RH#, Wu FF#, Lu M#, Shu XD, Ding JH, Wu G, Hu G*, 2016
- Fluoxetine Inhibits NLRP3 Inflammasome Activation: Implication in Depression, Du RH, Tan J, Sun XY, Lu M, Ding JH, Hu G, 2016
- Endophilin A2 Influences Volume-Regulated Chloride Current by Mediating ClC-3 Trafficking in Vascular Smooth Muscle Cells, Liu CZ#, Li XY#, Du RH#, Gao M, Ma MM, Li FY, Huang EW, Sun HS, Wang GL, Guan YY, 2016
- β-Arrestin 2 mediates the anti-inflammatory effects of fluoxetine in lipopolysaccharide-stimulated microglial cells, Du RW, Du RH*, Bu WG*, 2014
- Kir6.2-containing ATP-sensitive K(+) channel is required for cardioprotection of resveratrol in mice, Du RH, Dai T, Cao WJ, Lu M, Ding JH, Hu G, 2014
- Kir6.2 knockout aggravates lipopolysaccharide-induced mouse liver injury via enhancing NLRP3 inflammasome activation, Du RH, Tan J, Yan N, Wang L, Qiao C, Ding JH, Lu M, Hu G, 2014
