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Hua Zhang
Life Science
Huazhong Agricultural University
Hubei
Language: Chinese, English
Gene Regulation
Mycobacterium Tuberculosis
Drug Resistance
Protein-Protein Interaction
Protein-Nucleic Acid Interaction
Microbiology
Biochemistry
Molecular Biology
Pathogen
Antibiotic Resistance
Areas of Focus
- Research on gene regulation of Mycobacterium tuberculosis growth and drug resistance from protein-protein and protein-nucleic acid interactions
Work Experience
- 2008-present - Huazhong Agricultural University, College of Life Science and Technology - Lecturer, Associate Professor
Academic Background & Achievements
- 1994-1998 Bachelor of Engineering: Hunan Agricultural University, Food Engineering
- 2000-2003 Master of Science: Southwest Agricultural University, Microbiology
- 2003-2008 Doctor of Science: Institute of Applied Ecology, Chinese Academy of Sciences, Microbiology
Publications
- NapM, a new nucleoid-associated protein, broadly regulates gene expression and affects mycobacterial resistance to anti-tuberculosis drugs., Liu Y, Wang H, Cui T, Zhou X, Jia Y, Zhang H*, He ZG*., 2016
- Functional characterization of DnaB helicase and its modulation by single-stranded DNA-binding protein in Mycobacterium tuberculosis., Zhang H, Zhang Z, Yang J, He ZG., 2014
- A novel marRAB operon contributes to the rifampicin resistance in Mycobacterium smegmatis., Zhang H, Gao L, Zhang J, Li W, Yang M, Zhang H, Gao C, He ZG., 2014
- Mycobacterium smegmatis Lsr2 physically and functionally interacts with a new flavoprotein involved in bacterial resistance to oxidative stress., Du Y, Zhang H, He Y, Huang F, He ZG., 2012
- Characterization of amino acid residues essential for tetramer formation and DNA-binding activity of ssDNA-binding protein of Mycobacterium tuberculosis., Zhang H#, Tian Y#, Liu Z, Huang F, Hu L, He ZG., 2011
- Characterization of a bifunctional β-Lactamase/Ribonuclease and its interaction with a chaperone-like protein in the pathogen Mycobacterium tuberculosis H37Rv., Sun L, Zhang L, Zhang H, He ZG., 2011
- Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv., Wang Y, Cui T, Zhang C, Yang M, Huang Y, Li W, Zhang L, Gao C, He Y, Li Y, Huang F, Zeng J, Huang C, Yang Q, Tian Y, Zhao C, Chen H, Zhang H, He ZG., 2010
- The characterization of conserved binding motifs and potential target genes for M. tuberculosis MtrAB reveals a link between the two-component system and the drug resistance of M. smegmatis., Li Y, Zeng J, Zhang H, He ZG., 2010
- Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules., Yang M, Gao C, Wang Y, Zhang H, He ZG., 2010
- Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China., Zhang H, Bi L, Li C, Sun Z, Deng J, Zhang XE., 2009
- Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase., Zhang H, Deng J, Bi L, Zhou Y, Zhang Z, Zhang C, Zhang Y. Zhang XE., 2008
Awards
- 2012-2014: Third Prize for Teaching Quality at Huazhong Agricultural University
