Professor | 张华 | 数字化转型顾问

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Name	张华
Contact Information	zhanghua@mail.hzau.edu.cn
Language ability	中文, 英文
Province	湖北

Upload Avatar (500 x 500)

Name

张华

Contact Information

zhanghua@mail.hzau.edu.cn

Language ability

中文, 英文

Province

湖北

University/Lab Affiliation and Title	华中农业大学
Faculty	Life Sciences
Academic Background & Achievements	1994-1998 工学学士学位：湖南农业大学，食品工程 2000-2003 理学硕士学位：西南农业大学，微生物学 2003-2008 理学博士学位：中国科学院沈阳应用生态研究所，微生物学
Work Experience	2008-至今 - 华中农业大学生命科学技术学院 - 讲师，副教授
Awards	2012-2014年：华中农业大学教学质量三等奖

University/Lab Affiliation and Title

华中农业大学

Faculty

Life Sciences

Academic Background & Achievements

1994-1998 工学学士学位：湖南农业大学，食品工程
2000-2003 理学硕士学位：西南农业大学，微生物学
2003-2008 理学博士学位：中国科学院沈阳应用生态研究所，微生物学

Work Experience

2008-至今 - 华中农业大学生命科学技术学院 - 讲师，副教授

Awards

2012-2014年：华中农业大学教学质量三等奖

Areas of Focus	从蛋白质-蛋白质相互作用及蛋白质-核酸相互作用出发，研究基因调控结核分枝杆菌生长及耐药相关的课题
Publications	NapM, a new nucleoid-associated protein, broadly regulates gene expression and affects mycobacterial resistance to anti-tuberculosis drugs., Liu Y, Wang H, Cui T, Zhou X, Jia Y, Zhang H, He ZG., 2016 Functional characterization of DnaB helicase and its modulation by single-stranded DNA-binding protein in Mycobacterium tuberculosis., Zhang H, Zhang Z, Yang J, He ZG., 2014 A novel marRAB operon contributes to the rifampicin resistance in Mycobacterium smegmatis., Zhang H, Gao L, Zhang J, Li W, Yang M, Zhang H, Gao C, He ZG., 2014 Mycobacterium smegmatis Lsr2 physically and functionally interacts with a new flavoprotein involved in bacterial resistance to oxidative stress., Du Y, Zhang H, He Y, Huang F, He ZG., 2012 Characterization of amino acid residues essential for tetramer formation and DNA-binding activity of ssDNA-binding protein of Mycobacterium tuberculosis., Zhang H#, Tian Y#, Liu Z, Huang F, Hu L, He ZG., 2011 Characterization of a bifunctional β-Lactamase/Ribonuclease and its interaction with a chaperone-like protein in the pathogen Mycobacterium tuberculosis H37Rv., Sun L, Zhang L, Zhang H, He ZG., 2011 Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv., Wang Y, Cui T, Zhang C, Yang M, Huang Y, Li W, Zhang L, Gao C, He Y, Li Y, Huang F, Zeng J, Huang C, Yang Q, Tian Y, Zhao C, Chen H, Zhang H, He ZG., 2010 The characterization of conserved binding motifs and potential target genes for M. tuberculosis MtrAB reveals a link between the two-component system and the drug resistance of M. smegmatis., Li Y, Zeng J, Zhang H, He ZG., 2010 Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules., Yang M, Gao C, Wang Y, Zhang H, He ZG., 2010 Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China., Zhang H, Bi L, Li C, Sun Z, Deng J, Zhang XE., 2009 Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase., Zhang H, Deng J, Bi L, Zhou Y, Zhang Z, Zhang C, Zhang Y. Zhang XE., 2008

Areas of Focus

从蛋白质-蛋白质相互作用及蛋白质-核酸相互作用出发，研究基因调控结核分枝杆菌生长及耐药相关的课题

Publications

NapM, a new nucleoid-associated protein, broadly regulates gene expression and affects mycobacterial resistance to anti-tuberculosis drugs., Liu Y, Wang H, Cui T, Zhou X, Jia Y, Zhang H*, He ZG*., 2016
Functional characterization of DnaB helicase and its modulation by single-stranded DNA-binding protein in Mycobacterium tuberculosis., Zhang H, Zhang Z, Yang J, He ZG., 2014
A novel marRAB operon contributes to the rifampicin resistance in Mycobacterium smegmatis., Zhang H, Gao L, Zhang J, Li W, Yang M, Zhang H, Gao C, He ZG., 2014
Mycobacterium smegmatis Lsr2 physically and functionally interacts with a new flavoprotein involved in bacterial resistance to oxidative stress., Du Y, Zhang H, He Y, Huang F, He ZG., 2012
Characterization of amino acid residues essential for tetramer formation and DNA-binding activity of ssDNA-binding protein of Mycobacterium tuberculosis., Zhang H#, Tian Y#, Liu Z, Huang F, Hu L, He ZG., 2011
Characterization of a bifunctional β-Lactamase/Ribonuclease and its interaction with a chaperone-like protein in the pathogen Mycobacterium tuberculosis H37Rv., Sun L, Zhang L, Zhang H, He ZG., 2011
Global protein-protein interaction network in the human pathogen Mycobacterium tuberculosis H37Rv., Wang Y, Cui T, Zhang C, Yang M, Huang Y, Li W, Zhang L, Gao C, He Y, Li Y, Huang F, Zeng J, Huang C, Yang Q, Tian Y, Zhao C, Chen H, Zhang H, He ZG., 2010
The characterization of conserved binding motifs and potential target genes for M. tuberculosis MtrAB reveals a link between the two-component system and the drug resistance of M. smegmatis., Li Y, Zeng J, Zhang H, He ZG., 2010
Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules., Yang M, Gao C, Wang Y, Zhang H, He ZG., 2010
Mutations found in the pncA gene of Mycobacterium tuberculosis in clinical pyrazinamide-resistant isolates from a local region of China., Zhang H, Bi L, Li C, Sun Z, Deng J, Zhang XE., 2009
Characterization of Mycobacterium tuberculosis nicotinamidase/pyrazinamidase., Zhang H, Deng J, Bi L, Zhou Y, Zhang Z, Zhang C, Zhang Y. Zhang XE., 2008

基因调控结核分枝杆菌耐药性蛋白质-蛋白质相互作用蛋白质-核酸相互作用微生物学生物化学分子生物学病原体抗生素耐药性

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