1999.9-2003.6 Bachelor: Wuhan University, School of Life Sciences, Biotechnology
2003.9-2008.6 Doctorate: Wuhan University, School of Life Sciences, Cell Biology
2009.2-2012.4 - University of Chicago, Department of Hematology and Oncology - Postdoctoral Researcher
2012.5-2013.12 - Stanford University, Cardiovascular Institute - Postdoctoral Researcher
2014.1-2020.9 - Wuhan University, School of Basic Medical Sciences - Associate Professor
2020.10-present - Huazhong Agricultural University, School of Biomedical and Health Sciences - Professor
Wuhan University Luojia Young Scholar (2014)
Wuhan University Zhu Yubi Medical Award (2014)
Hubei Province Talent Program (2016)
Hubei Province Natural Science and Technology Progress Award Second Prize (2021)
Research
Role and regulatory mechanisms of non-coding RNA in tissue homeostasis and tumor development Intercellular communication and immune cell regulatory networks in hematopoietic homeostasis and leukemia
circRIP: an accurate tool for identifying circRNA-RBP interactions, Dong X, Chen K, Chen W, Wang J, Chang L, Deng J, Wei L, Han L, Huang C, He C, 2022
YTHDF1 promotes mRNA degradation via YTHDF1-AGO2 interaction and phase separation, Li J, Chen K, Dong X, Xu Y, Sun Q, Wang H, Chen Z, Liu C, Liu R, Yang Z, Mei X, Zhang R, Chang L, Tian Z, Chen J, Liang K, He C, Luo M, 2022
CSCD 2.0: An integrated interactional database of cancer-specific circular RNA, Feng J, Chen W, Dong X, Wang J, Mei X, Deng J, Yang S, Zhuo C, Huang X, Shao L, Zhang R, Guo J, Ma R, Liu J, Li F, Wu Y, Han L, He C, 2021
ADEIP: an integrated platform of age-dependent expression and immune profiles across human tissues, Liu X, Chen W, Fang Y, Yang S, Chang L, Chen X, Ye H, Tang X, Zhong S, Zhang W, Dong Z, Han L, He C, 2021
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy, Shao L, Jiang G, Yang X, Zeng M, Cheng J, Kong S, Dong X, Chen T, Han S, Yin J, Liu W, He X, He C, Peng B, 2021
CircRNA inhibits DNA damage repair by interacting with host gene, Xu X, Zhang J, Tian Y, Gao Y, Dong X, Chen W, Yuan X, Yin W, Xu J, Chen K, He C, Wei L, 2020
The RNA N(6)-methyladenosine modification landscape of human fetal tissues, Xiao S, Cao S, Huang Q, Xia L, Deng M, Yang M, Jia G, Liu X, Shi J, Wang W, Li Y, Liu S, Zhu H, Tan K, Luo Q, Zhong M, He C, Xia L, 2019
Genome-wide identification of cancer-specific alternative splicing in circRNA, Feng J, Chen K, Dong X, Xu X, Jin Y, Zhang X, Chen W, Han Y, Shao L, Gao Y, He C, 2019
CVm6A: A Visualization and Exploration Database for m6As in Cell Lines, Han Y, Feng J, Xia L, Dong X, Zhang X, Zhang S, Miao Y, Xu Q, Xiao S, Zuo Z, Xia L, He C, 2019
CircView: a visualization and exploration tool for circular RNAs, Feng J, Xiang Y, Xia S, Liu H, Wang J, Ozguc F, Lei L, Kong R, Diao L, He C, Han L, 2018
Genome-wide characterization of lncRNAs in acute myeloid leukemia, Lei L, Xia S, Liu D, Li X, Feng J, Zhu Y, Hu J, Xia L, Guo L, Chen F, Cheng H, Chen K, Hu H, Chen X, Li F, Zhong S, Mittal N, Yang G, Qian Z, Han L, He C, 2018
CSCD: A database for cancer-specific circular RNAs, Xia S, Feng J, Chen K, Ma Y, Gong J, Cai F, Jin Y, Gao Y, Xia L, Chang H, Wei L, Han L, He C, 2018
Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes, Xia S, Feng J, Lei L, Hu J, Xia L, Wang J, Xiang Y, Liu L, Zhong S, Han L, He C, 2017
Systematic Characterization of Long Non-Coding RNAs Reveals the Contrasting Coordination of Cis- and Trans- Molecular Regulation in Human Fetal and Adult Heart, He C, Hu H, Wilson KD, Wu H, Feng J, Xia S, Churko J, Qu K, Chang HY, Wu JC, 2016
Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study, Li Z, Herold T, He C, Valk PJ, Chen P, Jurinovic V, Mansmann U, Radmacher MD, Maharry KS, Sun M, Yang X, Huang H, Jiang X, Sauerland MC, Büchner T, Hiddemann W, Elkahloun A, Neilly MB, Zhang Y, Larson RA, Le Beau MM, Caligiuri MA, Döhner K, Bullinger L, Liu PP, Delwel R, Marcucci G, Lowenberg B, Bloomfield CD, Rowley JD, Bohlander SK, Chen J, 2013
Young intragenic miRNAs are less coexpressed with host genes than old ones: implications of miRNA-host gene coevolution, He C, Li Z, Chen P, Huang H, Hurst LD, Chen J, 2012
Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia, Mi S, Li Z, Chen P, He C, Cao D, Elkahloun A, Lu J, Pelloso LA, Wunderlich M, Huang H, Luo RT, Sun M, He M, Neilly MB, Zeleznik-Le NJ, Thirman MJ, Mulloy JC, Liu PP, Rowley JD, Chen J, 2010
A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis, He C, Zhou F, Zuo Z, Cheng H, Zhou R, 2009
GATA family of transcription factors of vertebrates: phylogenetics and chromosomal synteny, He C, Cheng H, Zhou R, 2007
Genome-wide detection of testis- and testicular cancer-specific alternative splicing, He C, Zuo Z, Chen H, Zhang L, Zhou F, Cheng H, Zhou R, 2007
Area of Focus
Molecular Genetics | Epigenetics | Tumors | Liver Cancer | Esophageal Cancer | Gastric Cancer | Rna Editing | Tumor Development | Cancer Stem Cells | Regulatory Mechanisms
