Professor | Jin Xu | Asia Growth Partners

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Name	Jin Xu
Contact Information	xujin7@mail.sysu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Jin Xu

Contact Information

xujin7@mail.sysu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Sun Yat-Sen University
Faculty	Life Sciences
Academic Background & Achievements	2019-present: Professor at Sun Yat-sen University 2014-2019: Postdoctoral Researcher at Stanford University School of Medicine (Supervisor: Howard Y. Chang) 2008-2014: Ph.D. in Bioinformatics, Beijing Institute of Genomics, Chinese Academy of Sciences (Supervisor: Chung-I Wu) 2003-2007: Bachelor's in Software Engineering, Northeast Normal University 2019: Recruited under Sun Yat-sen University's 'Hundred Talents Program'
Work Experience	2019-present - Sun Yat-sen University - Professor 2014-2019 - Stanford University School of Medicine - Postdoctoral Researcher
Awards	2019: Recruited under Sun Yat-sen University's 'Hundred Talents Program'

University/Lab Affiliation and Title

Sun Yat-Sen University

Faculty

Life Sciences

Academic Background & Achievements

2019-present: Professor at Sun Yat-sen University
2014-2019: Postdoctoral Researcher at Stanford University School of Medicine (Supervisor: Howard Y. Chang)
2008-2014: Ph.D. in Bioinformatics, Beijing Institute of Genomics, Chinese Academy of Sciences (Supervisor: Chung-I Wu)
2003-2007: Bachelor's in Software Engineering, Northeast Normal University
2019: Recruited under Sun Yat-sen University's 'Hundred Talents Program'

Work Experience

2019-present - Sun Yat-sen University - Professor
2014-2019 - Stanford University School of Medicine - Postdoctoral Researcher

Awards

2019: Recruited under Sun Yat-sen University's 'Hundred Talents Program'

Areas of Focus	Single-cell sequencing technology Comparative genomics and functional genomics Mitochondrial mutations in cells
Publications	MitoSort: Robust Demultiplexing of Pooled Single-cell Genomics Data Using Endogenous Mitochondrial Variants., Zhongjie Tang, Weixing Zhang, Peiyu Shi, Sijun Li, Xinhui Li, Yueming Li, Yicong Xu, Yaqing Shu, Zheng Hu, Jin Xu, 2024 Regulatory mechanisms orchestrating cellular diversity of Cd36+ olfactory sensory neurons revealed by scRNA-seq and scATAC-seq analysis., Jiawen Yang, Peiyu Shi, Yiheng Li, Yachao Zuo, Yage Nie, Tao Xu, Dongjie Peng, Ziyang An, Tingting Huang, Jingyi Zhang, Weixing Zhang, Yicong Xu, Zhongjie Tang, Anan Li, Jin Xu, 2024 Soma-germline communication drives sex maintenance in the Drosophila testis., Rui Zhang, Peiyu Shi, Shuyang Xu, Zhe Ming, Zicong Liu, Yuanyuan He, Junbiao Dai, Erika Matunis, Jin Xu, Qing Ma, 2024 Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer’s disease., Min Yu, Yage Nie, Jiawen Yang, Shilun Yang, Rui Li, Varsha Rao, Xiaoyan Hu, Cheng Fang, Simeng Li, Dengpan Song, Fuyou Guo, Michael P Snyder, Howard Y Chang, Calvin J Kuo, Jin Xu, Junlei Chang, 2023 Fundamental and practical approaches for single-cell ATAC-seq analysis., Peiyu Shi, Yage Nie, Jiawen Yang, Weixing Zhang, Zhongjie Tang, Jin Xu, 2022 A Genetic Bottleneck of Mitochondiral DNA during Human Lymphocyte Development., Zhongjie Tang, Zhaolian Lu, Baizhen Chen, Weixing Zhang, Howard Y. Chang, Zheng Hu, Jin Xu, 2022 Run or Die in the Evolution of New MicroRNAs—Testing the Red Queen Hypothesis on De Novo New Genes., Yixin Zhao, Guang-An Lu, Hao Yang, Pei Lin, Zhongqi Liufu, Tian Tang, Jin Xu, 2021 Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA., Xu, Jin; Nuno, Kevin; Litzenburger, Ulrike M; Qi, Yanyan; Corces, M Ryan; Majeti, Ravindra; Chang, Howard Y., 2019 Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element., Cho, Seung Woo; Xu, Jin; Sun, Ruping; Mumbach, Maxwell R; Carter, Ava C; Chen, Y Grace; Yost, Kathryn E; Kim, Jeewon; He, Jing; Nevins, Stephanie A; et.al, 2018 Free-living human cells reconfigure their chromosomes in the evolution back to uni-cellularity., Xu, Jin; Peng, Xinxin; Chen, Yuxin; Zhang, Yuezheng; Ma, Qin; Liang, Liang; Carter, Ava C; Lu, Xuemei; Wu, Chung-I., 2017 Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells., Xu, Jin; Carter, Ava C; Gendrel, Anne-Valerie; Attia, Mikael; Loftus, Joshua; Greenleaf, William J; Tibshirani, Robert; Heard, Edith; Chang, Howard Y., 2017 Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome., Huang, Wei-Hsiang; Guenthner, Casey J; Xu, Jin; Nguyen, Tiffany; Schwarz, Lindsay A; Wilkinson, Alex W; Gozani, Or; Chang, Howard Y; Shamloo, Mehrdad; Luo, Liqun., 2016 Structural organization of the inactive X chromosome in the mouse., Giorgetti, Luca; Lajoie, Bryan R; Carter, Ava C; Attia, Mikael; Zhan, Ye; Xu, Jin; Chen, Chong Jian; Kaplan, Noam; Chang, Howard Y; Heard, Edith., 2016 The evolution of evolvability in microRNA target sites in vertebrates., Xu, Jin; Zhang, Rui; Shen, Yang; Liu, Guojing; Lu, Xuemei; Wu, Chung-I., 2013

Areas of Focus

Single-cell sequencing technology
Comparative genomics and functional genomics
Mitochondrial mutations in cells

Publications

MitoSort: Robust Demultiplexing of Pooled Single-cell Genomics Data Using Endogenous Mitochondrial Variants., Zhongjie Tang, Weixing Zhang, Peiyu Shi, Sijun Li, Xinhui Li, Yueming Li, Yicong Xu, Yaqing Shu, Zheng Hu, Jin Xu, 2024
Regulatory mechanisms orchestrating cellular diversity of Cd36+ olfactory sensory neurons revealed by scRNA-seq and scATAC-seq analysis., Jiawen Yang, Peiyu Shi, Yiheng Li, Yachao Zuo, Yage Nie, Tao Xu, Dongjie Peng, Ziyang An, Tingting Huang, Jingyi Zhang, Weixing Zhang, Yicong Xu, Zhongjie Tang, Anan Li, Jin Xu, 2024
Soma-germline communication drives sex maintenance in the Drosophila testis., Rui Zhang, Peiyu Shi, Shuyang Xu, Zhe Ming, Zicong Liu, Yuanyuan He, Junbiao Dai, Erika Matunis, Jin Xu, Qing Ma, 2024
Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer’s disease., Min Yu, Yage Nie, Jiawen Yang, Shilun Yang, Rui Li, Varsha Rao, Xiaoyan Hu, Cheng Fang, Simeng Li, Dengpan Song, Fuyou Guo, Michael P Snyder, Howard Y Chang, Calvin J Kuo, Jin Xu, Junlei Chang, 2023
Fundamental and practical approaches for single-cell ATAC-seq analysis., Peiyu Shi, Yage Nie, Jiawen Yang, Weixing Zhang, Zhongjie Tang, Jin Xu, 2022
A Genetic Bottleneck of Mitochondiral DNA during Human Lymphocyte Development., Zhongjie Tang, Zhaolian Lu, Baizhen Chen, Weixing Zhang, Howard Y. Chang, Zheng Hu, Jin Xu, 2022
Run or Die in the Evolution of New MicroRNAs—Testing the Red Queen Hypothesis on De Novo New Genes., Yixin Zhao, Guang-An Lu, Hao Yang, Pei Lin, Zhongqi Liufu, Tian Tang, Jin Xu, 2021
Single-cell lineage tracing by endogenous mutations enriched in transposase accessible mitochondrial DNA., Xu, Jin; Nuno, Kevin; Litzenburger, Ulrike M; Qi, Yanyan; Corces, M Ryan; Majeti, Ravindra; Chang, Howard Y., 2019
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element., Cho, Seung Woo; Xu, Jin; Sun, Ruping; Mumbach, Maxwell R; Carter, Ava C; Chen, Y Grace; Yost, Kathryn E; Kim, Jeewon; He, Jing; Nevins, Stephanie A; et.al, 2018
Free-living human cells reconfigure their chromosomes in the evolution back to uni-cellularity., Xu, Jin; Peng, Xinxin; Chen, Yuxin; Zhang, Yuezheng; Ma, Qin; Liang, Liang; Carter, Ava C; Lu, Xuemei; Wu, Chung-I., 2017
Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells., Xu, Jin; Carter, Ava C; Gendrel, Anne-Valerie; Attia, Mikael; Loftus, Joshua; Greenleaf, William J; Tibshirani, Robert; Heard, Edith; Chang, Howard Y., 2017
Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome., Huang, Wei-Hsiang; Guenthner, Casey J; Xu, Jin; Nguyen, Tiffany; Schwarz, Lindsay A; Wilkinson, Alex W; Gozani, Or; Chang, Howard Y; Shamloo, Mehrdad; Luo, Liqun., 2016
Structural organization of the inactive X chromosome in the mouse., Giorgetti, Luca; Lajoie, Bryan R; Carter, Ava C; Attia, Mikael; Zhan, Ye; Xu, Jin; Chen, Chong Jian; Kaplan, Noam; Chang, Howard Y; Heard, Edith., 2016
The evolution of evolvability in microRNA target sites in vertebrates., Xu, Jin; Zhang, Rui; Shen, Yang; Liu, Guojing; Lu, Xuemei; Wu, Chung-I., 2013

Single-Cell Sequencing Scatacseq Scrnaseq Epigenetics Neuroscience Comparative Genomics Functional Genomics Mitochondrial Mutations Cellular Heterogeneity Bioinformatics

Chenfei Wang - Tongji University

Xiaocui Xu - Tongji University

Aiping Lu - Tongji University

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