Professor | Yinhua Zhu | Asia Growth Partners

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Name	Yinhua Zhu
Contact Information	zhuyinhua@cau.edu.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Yinhua Zhu

Contact Information

zhuyinhua@cau.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	China Agricultural University
Faculty	department of nutrition and health
Academic Background & Achievements	2010.9-2017.7 PhD: China Agricultural University 2006.9-2010.7 Bachelor's: Huazhong Agricultural University
Work Experience	2023.6-present - China Agricultural University - Associate Professor 2021.9-2023.5 - China Academy of Chinese Medical Sciences - Assistant Researcher 2017.9-2021.8 - Peking University - Postdoctoral Research
Awards	Sanofi-Cell Research Outstanding Paper Award (2020): For the paper on β-galactosidase-targeted prodrug

University/Lab Affiliation and Title

China Agricultural University

Faculty

department of nutrition and health

Academic Background & Achievements

2010.9-2017.7 PhD: China Agricultural University
2006.9-2010.7 Bachelor's: Huazhong Agricultural University

Work Experience

2023.6-present - China Agricultural University - Associate Professor
2021.9-2023.5 - China Academy of Chinese Medical Sciences - Assistant Researcher
2017.9-2021.8 - Peking University - Postdoctoral Research

Awards

Sanofi-Cell Research Outstanding Paper Award (2020): For the paper on β-galactosidase-targeted prodrug

Areas of Focus	Chemical biology analysis of protein targets and mechanisms of natural products Development of high-activity anti-aging agents
Publications	Photoaffinity Labeling Coupled with Proteomics Identify PDI-ADAM17 Module is Targeted by (−)-Vinigrol to Induce TNFR1 Shedding and Ameliorate Rheumatoid Arthritis in Mice, Zhu Y, Wang L, Li J, Zhao Y, Yu X, Deng X, Liu J, Yang F, Zhang Y, Yu J, Lai L, Wang C, Li Z, Wang L and Luo T, 2024 Microplastics exposure causes the senescence of human lung epithelial cells and mouse lungs by inducing ROS signaling, Jin W, Zhang W, Tang H, Wang P, Zhang Y, Liu S, Qiu J, Chen H, Wang L, Wang R, Sun Y, Liu P, Tang H and Zhu Y, 2024 Gambogic acid suppresses the pentose phosphate pathway by covalently inhibiting 6PGD protein in cancer cells, Zhu Y, Zhang Y, Zhang Q, Ma A, Zhang Y, Wang C, Tang H, Gao P, Guo Q, Xia F, Tang H, Xu C, Wang J, 2022 Oridonin acts as a novel senolytics by targeting Glutathione S-Transferases to activate ROS-p38 signaling axis in senescent cells, Zhang Y, Zhang Q, Chu Z, Chen L, Chen J, Yang Y, Tang H, Cheng G, Ma A, Zhang Y, Wang C, Gao P, Xia F, Guo Q, Shi Q, Han G, Wang J and Zhu Y, 2022 Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice, Cai Y, Zhou H, Zhu Y, Sun Q, Ji Y, Xue A, Wang Y, Chen W, Yu X, Wang L, Chen H, Li C, Luo T and Deng H, 2020 Effective treatment of SARS-CoV-2-infected rhesus macaques by attenuating inflammation, Lu S, Zhao J, Dong J, Liu H, Zhu Y, Li H, Liu L, Yang Y, Sun S, Song Y, Zhao Y, She R, Luo T, Deng H, and Peng X, 2020 Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona, Tang H, Zhang Y, Yang T, Wang C, Zhu Y, Qiu L, Liu J, Song Y, Zhou L, Zhang J, Wong YK, Liu Y, Xu C, Wang H, Wang J, 2023 BAK1 plays contrasting roles in regulating abscisic acid-induced stomatal closure and abscisic acid-inhibited primary root growth in Arabidopsis, Deng J, Kong L, Zhu Y, Pei D, Chen X, Wang Y, Qi J, Song C, Yang S, Gong Z, 2022 Tonsillar Microbiome-Derived Lantibiotics Induce Structural Changes of IL-6 and IL-21 Receptors and Modulate Host Immunity, Li J, Jin J, Li S, Zhong Y, Jin Y, Zhang X, Xia B, Zhu Y, Guo R, Sun X, Guo J, Hu F, Xiao W, Huang F, Ye H, Li R, Zhou Y, Xiang X, Yao H, Yan Q, Su L, Wu L, Luo T, Liu Y, Guo X, Qin J, Qi H, He J, Wang J, Li Z, 2022 Surface chemistry of graphene tailoring the activity of digestive enzymes by modulating interfacial molecular interactions, Tang H, Yang T, Chen L, Zhang Y, Zhu Y, Wang C, Liu D, Guo Q, Cheng G, Xia F, Zhong T and Wang J, 2023 How eluents define proteomic fingerprinting of protein corona on nanoparticles, Qiu L, Zhang Y, Wei G, Wang C, Zhu Y, Yang T, Chu Z, Gao P, Cheng G, Ma A, Kwan Wong Y, Zhang J, Xu C, Wang J, Tang H, 2023 Chemoproteomics reveals Sofalcone inhibits the inflammatory response of Caco-2 cells by covalently targeting HMGB1, Yang T, Liu D, Li Y, Zhang Y, Zhu Y, Zhang J, Wang C, Zhang S, Wong YK, Luo P, Guo Q, Xia F, Zhong T, Tang H, Wang J, 2023 Chemical proteomic profiling with photoaffinity labeling strategy identifies antimalarial targets of artemisinin, Gao P, Chen J, Sun P, Wang J, Tang H, Xia F, Gu L, Zhang H, Wang C, Wong Y, Zhu Y, Xu C, Wang J, 2023 Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress, Wang Q, Huang Y, Li Y, Zhang L, Tang H, Zhang J, Cheng G, Zhao M, Lu T, Zhang Q, Luo P, Zhu Y, Xia F, Zhang Y, Liu D, Wang C, Li H, Qiu C, Wang J, Guo Q, 2022

Areas of Focus

Chemical biology analysis of protein targets and mechanisms of natural products
Development of high-activity anti-aging agents

Publications

Photoaffinity Labeling Coupled with Proteomics Identify PDI-ADAM17 Module is Targeted by (−)-Vinigrol to Induce TNFR1 Shedding and Ameliorate Rheumatoid Arthritis in Mice, Zhu Y, Wang L, Li J, Zhao Y, Yu X, Deng X, Liu J, Yang F, Zhang Y, Yu J, Lai L, Wang C, Li Z, Wang L and Luo T, 2024
Microplastics exposure causes the senescence of human lung epithelial cells and mouse lungs by inducing ROS signaling, Jin W, Zhang W, Tang H, Wang P, Zhang Y, Liu S, Qiu J, Chen H, Wang L, Wang R, Sun Y, Liu P, Tang H and Zhu Y, 2024
Gambogic acid suppresses the pentose phosphate pathway by covalently inhibiting 6PGD protein in cancer cells, Zhu Y, Zhang Y, Zhang Q, Ma A, Zhang Y, Wang C, Tang H, Gao P, Guo Q, Xia F, Tang H, Xu C, Wang J, 2022
Oridonin acts as a novel senolytics by targeting Glutathione S-Transferases to activate ROS-p38 signaling axis in senescent cells, Zhang Y, Zhang Q, Chu Z, Chen L, Chen J, Yang Y, Tang H, Cheng G, Ma A, Zhang Y, Wang C, Gao P, Xia F, Guo Q, Shi Q, Han G, Wang J and Zhu Y, 2022
Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice, Cai Y, Zhou H, Zhu Y, Sun Q, Ji Y, Xue A, Wang Y, Chen W, Yu X, Wang L, Chen H, Li C, Luo T and Deng H, 2020
Effective treatment of SARS-CoV-2-infected rhesus macaques by attenuating inflammation, Lu S, Zhao J, Dong J, Liu H, Zhu Y, Li H, Liu L, Yang Y, Sun S, Song Y, Zhao Y, She R, Luo T, Deng H, and Peng X, 2020
Cholesterol modulates the physiological response to nanoparticles by changing the composition of protein corona, Tang H, Zhang Y, Yang T, Wang C, Zhu Y, Qiu L, Liu J, Song Y, Zhou L, Zhang J, Wong YK, Liu Y, Xu C, Wang H, Wang J, 2023
BAK1 plays contrasting roles in regulating abscisic acid-induced stomatal closure and abscisic acid-inhibited primary root growth in Arabidopsis, Deng J, Kong L, Zhu Y, Pei D, Chen X, Wang Y, Qi J, Song C, Yang S, Gong Z, 2022
Tonsillar Microbiome-Derived Lantibiotics Induce Structural Changes of IL-6 and IL-21 Receptors and Modulate Host Immunity, Li J, Jin J, Li S, Zhong Y, Jin Y, Zhang X, Xia B, Zhu Y, Guo R, Sun X, Guo J, Hu F, Xiao W, Huang F, Ye H, Li R, Zhou Y, Xiang X, Yao H, Yan Q, Su L, Wu L, Luo T, Liu Y, Guo X, Qin J, Qi H, He J, Wang J, Li Z, 2022
Surface chemistry of graphene tailoring the activity of digestive enzymes by modulating interfacial molecular interactions, Tang H, Yang T, Chen L, Zhang Y, Zhu Y, Wang C, Liu D, Guo Q, Cheng G, Xia F, Zhong T and Wang J, 2023
How eluents define proteomic fingerprinting of protein corona on nanoparticles, Qiu L, Zhang Y, Wei G, Wang C, Zhu Y, Yang T, Chu Z, Gao P, Cheng G, Ma A, Kwan Wong Y, Zhang J, Xu C, Wang J, Tang H, 2023
Chemoproteomics reveals Sofalcone inhibits the inflammatory response of Caco-2 cells by covalently targeting HMGB1, Yang T, Liu D, Li Y, Zhang Y, Zhu Y, Zhang J, Wang C, Zhang S, Wong YK, Luo P, Guo Q, Xia F, Zhong T, Tang H, Wang J, 2023
Chemical proteomic profiling with photoaffinity labeling strategy identifies antimalarial targets of artemisinin, Gao P, Chen J, Sun P, Wang J, Tang H, Xia F, Gu L, Zhang H, Wang C, Wong Y, Zhu Y, Xu C, Wang J, 2023
Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress, Wang Q, Huang Y, Li Y, Zhang L, Tang H, Zhang J, Cheng G, Zhao M, Lu T, Zhang Q, Luo P, Zhu Y, Xia F, Zhang Y, Liu D, Wang C, Li H, Qiu C, Wang J, Guo Q, 2022

Chemical Biology Protein Targets Natural Products Mechanisms Anti-Aging High-Activity Agents Development Analysis Research

Jianping Xie - China Agricultural University

Jia Yue Guo - China Agricultural University

Zhang Hao - China Agricultural University

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