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Yue Zhao
yzhao30@cmu.edu.cn
Chinese, English, Japanese
Liaoning
China Medical University
Life Sciences
  • 2003 - PhD in Organ Function and Internal Medicine: Kyushu University, Japan
  • Postdoctoral Research: Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan
  • Liaoning Province Distinguished Professor
  • Member of the Youth Committee of the Chinese Society for Cell Biology
  • 2003-2008 - Postdoctoral Researcher - University of Tokyo, Japan
  • 2008-present - Director of Chromatin Biology Research Laboratory - China Medical University
  • 2013: Awarded 'March 8th Red Banner Holder' by China Medical University
  • 2015: Selected as Liaoning Province Distinguished Professor
  • 2016: Awarded 'Outstanding Communist Party Member in Shenyang Education and Science System'
  • 2016: Selected for Liaoning Province Hundred-Thousand-Ten Thousand Talent Project
  • 2017: Awarded 'Outstanding Scientific Worker' by China Medical University
  • 2018: Selected as High-Level Talent in Shenyang
  • 2018: Awarded 'National Advanced Individual of Returned Overseas Chinese and Their Relatives'
  • 2020: Awarded 'Liaoning Province Campus Pioneer Demonstration Post'
  • 2020: Awarded 'Outstanding Scientific Worker' by China Medical University
  • 2021: Awarded 'Outstanding Scientific Worker' by China Medical University
  • 2021: Nominated for 'Outstanding Party Affairs Worker in Liaoning Province Universities'
Screening, identification, and functional analysis of new genes
Regulation of gene transcription mediated by nuclear receptors
Role and molecular mechanism of nuclear receptor co-regulators in the development of hormone-related tumors
  • MYSM1 acts as a novel co-activator of ERa to confer antiestrogen resistance in breast cancer., Ruina Luan, Mingcong He, Hao Li, Yu Bai, Anqi Wang, Ge Sun, Baosheng Zhou, Manlin Wang, Chunyu Wang, Shengli Wang, Kai Zeng, Jianwei Feng, Lin Lin, Yuntao Wei, Shigeaki Kato, Qiang Zhang, Yue Zhao, 2023
  • USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma., Kai Zeng, Weiwen Xie, Chunyu Wang, Shengli Wang, Wei Liu, Yingjie Su, Lin Lin, Renlong Zou, Ge Sun, Baosheng Zhou, Manlin Wang, Ruina Luan, Yu Bai, Yunlong Huo, Shigeaki Kato, Xinping Zhong, Yue Zhao, 2023
  • BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression., Wei Liu, Shengi Wang, Linlin, Renlong Zou, Hongmiao Sun, Kai Zeng, Yi Wu, Yiling Li, Shigeaki Kato, Xiuxia Wang, Chunyu Wang, Yue Zhao, 2023
  • BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer., Ge Sun, Yuntao Wei, Baosheng Zhou, Manlin Wang, Ruina Luan, Yu Bai, Hao Li, Shan Wang, Dantong Zheng, Chunyu Wang, Shengli Wang, Kai Zeng, Shuchang Liu, Lin Lin, Mingcong He, Qiang Zhang, Yue Zhao, 2023
  • Ubiquitin-specific peptidase 14 maintains estrogen receptor α stability via its deubiquitination activity in endometrial cancer., Yingjie Su, Kai Zeng, Shuchang Liu, Yi Wu, Chunyu Wang, Shengli Wang, Lin Lin, Renlong Zou, Ge Sun, Ruina Luan, Baosheng Zhou, Yu Bai, Jumin Niu, Yi Zhang, Yue Zhao, 2023
  • RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression., Tingting Zhou, Shengli Wang, Xiaoyu Song, Wensu Liu, Fang Dong, Yunlong Huo, Renlong Zou, Chunyu Wang, Siyi Zhang, Wei Liu, Ge Sun, Lin Lin, Kai Zeng, Xiang Dong, Qiqiang Guo, Fei Yi, Zhuo Wang, Xiaoman Li, Bo Jiang, Liu Cao, Yue Zhao, 2022
  • High phosphorylated cyclin-dependent kinase 2 expression indicates poor prognosis of luminal androgen receptor triple-negative breast cancer., Zining Jin, Qingfu Zhang, Chunyu Wang, Shengli Wang, Lin Lin, Renlong Zou, Ge Sun, Kai Zeng, Baosheng Zhou, Yuxin Tong, Bo Chen, Yue Zhao, 2022
  • MOF upregulates the estrogen receptor α signaling pathway by its acetylase activity in hepatocellular carcinoma., Shan Wei, Wei Liu, Ning Sun, Yi Wu, Huijuan Song, Chunyu Wang, Shengli Wang, Renlong Zou, Lin Lin, Kai Zeng, Baosheng Zhou, Manlin Wang, Ruina Luan, Fan Yang, Yue Zhao, 2021
  • The function of BAP18 on modulation of androgen receptor action in luteinized granulosa cells from normal weight women with and without PCOS., Tianyu Tang, Jiao Jiao, Da Li, Ge Sun, Lin Lin, Chunyu Wang, Shengli Wang, Renlong Zou, Wensu Liu, Yue Zhao, Xiuxia Wang, 2021
  • PRPF6 promotes androgen receptor/androgen receptor-variant 7 actions in castration-resistant prostate cancer cells., Wei Liu, Chunyu Wang, Shengli Wang, Kai Zeng, Shan Wei, Ning Sun, Ge Sun, Manlin Wang, Renlong Zou, Wensu Liu, Lin Lin, Huijuan Song, Zining Jin, Yue Zhao, 2021
  • ATXN7L3 positively regulates SMAD7 transcription in hepatocellular carcinoma with growth inhibitory function., Ning Sun, Xinping Zhong, Shengli Wang, Kai Zeng, Hongmiao Sun, Ge Sun, Renlong Zou, Wei Liu, Wensu Liu, Lin Lin, Huijuan Song, Chi Lv, Chunyu Wang, Yue Zhao, 2020
  • An H3K4me3 reader, BAP18 as an adaptor of COMPASS-like core subunits co-activates ERα action and associates with the sensitivity of antiestrogen in breast cancer., Ge Sun, Chunyu Wang, Shengli Wang, Hongmiao Sun, Kai Zeng, Renlong Zou, Lin Lin, Wei Liu, Ning Sun, Huijuan Song, Wensu Liu, Tingting Zhou, Feng Jin, Zhongyan Shan, Yue Zhao, 2020
  • Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinoma., Huijuan Song, Ning Sun, Lin Lin, Shan Wei, Kai Zeng, Wei Liu, Chunyu Wang, Xinping Zhong, Manlin Wang, Shengli Wang, Baosheng Zhou, Chi Lv, Wensu Liu, Yue Zhao, 2020
  • BAP18 is involved in upregulation of CCND1/2 transcription to promote cell growth in oral squamous cell carcinoma., Xue Wang, Chunyu Wang, Guangqi Yan, Yuanyuan Kang, Ge Sun, Shengli Wang, Renlong Zou, Hongmiao Sun, Kai Zeng, Huijuan Song, Wei Liu, Ning Sun, Wensu Liu, Yue Zhao, 2020
  • ASH2L is involved in promotion of endometrial cancer progression via upregulation of PAX2 transcription., Kai Zeng, Yi Wu, Chunyu Wang, Shengli Wang, Hongmiao Sun, Renglong Zou, Ge Sun, Huijuan Song, Wei Liu, Ning Sun, Shan Wei, Wensu Liu, Yingjie Sun, Tingting Zhou, Yi Zhang, Yue Zhao, 2020
  • USP22 positively modulates ERα action via its deubiquitinase activity in breast cancer., Shengli Wang, Xinping Zhong, Chunyu Wang, Hao Luo, Lin Lin, Hongmiao Sun, Ge Sun, Kai Zeng, Renlong Zou, Wei Liu, Ning Sun, Huijuan Song, Wensu Liu, Qiang Zhang, Zhixuan Liao, Xiaochun Teng, Tingting Zhou, Xun Sun, Yue Zhao, 2020
  • Histone Acetyltransferase MOF is involved in suppression of endometrial cancer and maintenance of ERα stability., Yi Wu, Kai Zeng, Chunyu Wang, Shengli Wang, Hongmiao Sun, Wensu Liu, Xiuxia Wang, Jumin Niu, Shu-yan Cong, Xin Zhou, Yue Zhao, 2019
  • RNF8 identified as a co-activator of estrogen receptor α promotes cell growth in breast cancer., Shengli Wang, Hao Luo, Chunyu Wang, Hongmiao Sun, Ge Sun, Ning Sun, Kai Zeng, Renlong Zou, Rijiao Cong, Lei Yang, Da Li, Xin Zhou, Xinping Zhong, Lin Lin, Jiao Jiao, Guangqi Yan, Xue Wang, Liu Cao, Yue Zhao, 2017
  • BAP18 carrying a SANT domain coactivates androgen receptor action and promotes prostate cancer progression., Shiying Sun, Xinping Zhong, Chunyu Wang, Hongmiao Sun, Shengli Wang, Tingting Zhou, Renlong Zou, Lin Lin, Ning Sun, Ge Sun, Liu Cao, Yue Zhao, 2016
  • MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer., Chunyu Wang, Hongmiao Sun, Renlong Zou, Tingting Zhou, Shengli Wang, Shiying Sun, Changci Tong, Hao Luo, Yanshu Li, Zhenhua Li, Enhua Wang, Yuhua Chen, Liu Cao, Feng Li, Yue Zhao, 2015
  • MDC1 enhances estrogen receptor-mediated transactivation and contributes to breast cancer suppression., Renlong Zou, Xinping Zhong, Chunyu Wang, Hongmiao Sun, Shengli Wang, Lin Lin, Shiying Sun, Changci Tong, Hao Luo, Peng Gao, Yanshu Li, Tingting Zhou, Da Li, Liu Cao, Yue Zhao, 2015
  • Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1., Tingting Zhou, Shuyan Cong, Shiying Sun, Hongmiao Sun, Renlong Zou, Shengli Wang, Chunyu Wang, Yue Zhao, 2013
  • A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing., Yue Zhao, Guillaume Lang, Saya Ito, Jacques Bonnet, Eric Metzger, Shun Sawatsubashi, Eriko Suzuki, Xavie Le Guezennec, Hendrik G Stunnenberg, Aleksey Krasnov, Sofia Georgieva, Roland Schule, Ken-Ichi Takeyama, Shigeaki Kato, Laszlo Tora, Didier Devys, 2008
  • Co-repressive function of CBP for Androgen Receptor in pericentric heterochromatin in a Drosophila experimental model system., Yue Zhao, Ken-ichi Takeyama, Shun Sawatusbashi, Saya Ito, Eriko Suzuki, Kaoru Yamagata, Yuko Shirode, Masahiko Tanabe, Feng Li, Shuhei Kimura, Alexander Kouzmenko, Testuya Tabata, Shigeaki Kato, 2009
  • Activation Function-1 domain of Androgen Receptor Contribute to the Interaction between Subnuclear Splicing Factor Compartment and Nuclear Receptor Compartment., Yue Zhao, Kiminobu Goto, Masayuki Saitoh, Toshihiko Yanase, Masatoshi Nomura, Taijiro Okabe, Ryoichi Takayanagi, Hajime Nawata, 2002
Gene Screening Gene Identification Functional Analysis Nuclear Receptors Gene Transcription Co-Regulators Hormone-Related Tumors Molecular Mechanisms Epigenetics Chromatin Biology

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