Professor | Peiran Yang | Asia Growth Partners

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Name	Peiran Yang
Contact Information	peiranyang@ibms.pumc.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Peiran Yang

Contact Information

peiranyang@ibms.pumc.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking Union Medical College
Faculty	Basic Medical Sciences
Academic Background & Achievements	2008-2017 Bachelor's, Master's, and PhD: University of Cambridge 2017-2020 Postdoctoral: Harvard Medical School 2021- Talent Introduction: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College
Work Experience	2021-present - Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College - Group Leader, Doctoral Supervisor

University/Lab Affiliation and Title

Peking Union Medical College

Faculty

Basic Medical Sciences

Academic Background & Achievements

2008-2017 Bachelor's, Master's, and PhD: University of Cambridge
2017-2020 Postdoctoral: Harvard Medical School
2021- Talent Introduction: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College

Work Experience

2021-present - Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College - Group Leader, Doctoral Supervisor

Areas of Focus	Research on pulmonary vascular diseases and respiratory diseases
Publications	Sotatercept for Pulmonary Arterial Hypertension. (Letter to Editor), Yang P, Bocobo GA, Yu PB, 2021 The role of bone morphogenetic protein signaling in vascular calcification. (Review), Yang P, Troncone L, Augur ZM, Kim SSJ, McNeil ME, Yu PB, 2020 ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension., Yung LM, Yang P, Joshi S, Augur ZM, Kim SSJ, Bocobo GA, Dinter T, Troncone L, Chen PS, McNeil ME, Southwood M, Poli de Frias S, Knopf J, Rosas IO, Sako D, Pearsall RS, Quisel JD, Li G, Kumar R, Yu PB, 2020 A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Morrell NW, Davenport AP, Maguire JJ, 2019 Elabela/Toddler Is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP, 2017 [Pyr1]Apelin(1-12) is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr1]Apelin-13., Yang P, Kuc RE, Brame AL, Dyson A, Singer M, Glen RC, Cheriyan J, Wilkinson IB, Davenport AP, Maguire JJ, 2017 Cardiac action of the first G protein biased small molecule apelin agonist., Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP, 2016 Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. (Review), Yang P, Maguire JJ, Davenport AP, 2015

Areas of Focus

Research on pulmonary vascular diseases and respiratory diseases

Publications

Sotatercept for Pulmonary Arterial Hypertension. (Letter to Editor), Yang P, Bocobo GA, Yu PB, 2021
The role of bone morphogenetic protein signaling in vascular calcification. (Review), Yang P, Troncone L, Augur ZM, Kim SSJ, McNeil ME, Yu PB, 2020
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension., Yung LM, Yang P, Joshi S, Augur ZM, Kim SSJ, Bocobo GA, Dinter T, Troncone L, Chen PS, McNeil ME, Southwood M, Poli de Frias S, Knopf J, Rosas IO, Sako D, Pearsall RS, Quisel JD, Li G, Kumar R, Yu PB, 2020
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Morrell NW, Davenport AP, Maguire JJ, 2019
Elabela/Toddler Is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP, 2017
[Pyr1]Apelin(1-12) is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr1]Apelin-13., Yang P, Kuc RE, Brame AL, Dyson A, Singer M, Glen RC, Cheriyan J, Wilkinson IB, Davenport AP, Maguire JJ, 2017
Cardiac action of the first G protein biased small molecule apelin agonist., Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP, 2016
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. (Review), Yang P, Maguire JJ, Davenport AP, 2015

Pulmonary Hypertension Pneumoconiosis Chronic Obstructive Pulmonary Disease Molecular Mechanisms Pathophysiology Intervention Strategies New Targets Preclinical Experiments Translational Research Multidisciplinary Collaboration

Zhou Jing - Peking University

Lin He - Peking University

Fei Li - Fudan University

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