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Peiran Yang
Basic Medical Sciences
Peking Union Medical College
Beijing
Language: English, Chinese
Pulmonary Hypertension
Pneumoconiosis
Chronic Obstructive Pulmonary Disease
Molecular Mechanisms
Pathophysiology
Intervention Strategies
New Targets
Preclinical Experiments
Translational Research
Multidisciplinary Collaboration
Areas of Focus
- Research on pulmonary vascular diseases and respiratory diseases
Work Experience
- 2021-present - Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College - Group Leader, Doctoral Supervisor
Academic Background & Achievements
- 2008-2017 Bachelor's, Master's, and PhD: University of Cambridge
- 2017-2020 Postdoctoral: Harvard Medical School
- 2021- Talent Introduction: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College
Publications
- Sotatercept for Pulmonary Arterial Hypertension. (Letter to Editor), Yang P, Bocobo GA, Yu PB, 2021
- The role of bone morphogenetic protein signaling in vascular calcification. (Review), Yang P, Troncone L, Augur ZM, Kim SSJ, McNeil ME, Yu PB, 2020
- ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension., Yung LM, Yang P, Joshi S, Augur ZM, Kim SSJ, Bocobo GA, Dinter T, Troncone L, Chen PS, McNeil ME, Southwood M, Poli de Frias S, Knopf J, Rosas IO, Sako D, Pearsall RS, Quisel JD, Li G, Kumar R, Yu PB, 2020
- A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Morrell NW, Davenport AP, Maguire JJ, 2019
- Elabela/Toddler Is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP, 2017
- [Pyr1]Apelin(1-12) is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr1]Apelin-13., Yang P, Kuc RE, Brame AL, Dyson A, Singer M, Glen RC, Cheriyan J, Wilkinson IB, Davenport AP, Maguire JJ, 2017
- Cardiac action of the first G protein biased small molecule apelin agonist., Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP, 2016
- Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. (Review), Yang P, Maguire JJ, Davenport AP, 2015
