Professor | 杨沛然 | 数字化转型顾问

	Upload Avatar (500 x 500)
Name	杨沛然
Contact Information	peiranyang@ibms.pumc.edu.cn
Language ability	英语, 中文
Province	北京

Upload Avatar (500 x 500)

Name

杨沛然

Contact Information

peiranyang@ibms.pumc.edu.cn

Language ability

英语, 中文

Province

北京

University/Lab Affiliation and Title	北京协和医学院
Faculty	Basic Medical Sciences
Academic Background & Achievements	2008-2017 学士、硕士、博士学位: 英国剑桥大学 2017-2020 博士后: 美国哈佛大学医学院 2021- 引进人才: 中国医学科学院基础医学研究所&北京协和医学院基础学院
Work Experience	2021-至今 - 中国医学科学院基础医学研究所&北京协和医学院基础学院 - 课题组长, 博士研究生导师

University/Lab Affiliation and Title

北京协和医学院

Faculty

Basic Medical Sciences

Academic Background & Achievements

2008-2017 学士、硕士、博士学位: 英国剑桥大学
2017-2020 博士后: 美国哈佛大学医学院
2021- 引进人才: 中国医学科学院基础医学研究所&北京协和医学院基础学院

Work Experience

2021-至今 - 中国医学科学院基础医学研究所&北京协和医学院基础学院 - 课题组长, 博士研究生导师

Areas of Focus	肺血管病和呼吸系统疾病研究
Publications	Sotatercept for Pulmonary Arterial Hypertension. (Letter to Editor), Yang P, Bocobo GA, Yu PB, 2021 The role of bone morphogenetic protein signaling in vascular calcification. (Review), Yang P, Troncone L, Augur ZM, Kim SSJ, McNeil ME, Yu PB, 2020 ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension., Yung LM, Yang P, Joshi S, Augur ZM, Kim SSJ, Bocobo GA, Dinter T, Troncone L, Chen PS, McNeil ME, Southwood M, Poli de Frias S, Knopf J, Rosas IO, Sako D, Pearsall RS, Quisel JD, Li G, Kumar R, Yu PB, 2020 A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Morrell NW, Davenport AP, Maguire JJ, 2019 Elabela/Toddler Is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP, 2017 [Pyr1]Apelin(1-12) is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr1]Apelin-13., Yang P, Kuc RE, Brame AL, Dyson A, Singer M, Glen RC, Cheriyan J, Wilkinson IB, Davenport AP, Maguire JJ, 2017 Cardiac action of the first G protein biased small molecule apelin agonist., Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP, 2016 Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. (Review), Yang P, Maguire JJ, Davenport AP, 2015

Areas of Focus

肺血管病和呼吸系统疾病研究

Publications

Sotatercept for Pulmonary Arterial Hypertension. (Letter to Editor), Yang P, Bocobo GA, Yu PB, 2021
The role of bone morphogenetic protein signaling in vascular calcification. (Review), Yang P, Troncone L, Augur ZM, Kim SSJ, McNeil ME, Yu PB, 2020
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension., Yung LM, Yang P, Joshi S, Augur ZM, Kim SSJ, Bocobo GA, Dinter T, Troncone L, Chen PS, McNeil ME, Southwood M, Poli de Frias S, Knopf J, Rosas IO, Sako D, Pearsall RS, Quisel JD, Li G, Kumar R, Yu PB, 2020
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Nyimanu D, Williams TL, Crosby A, Buonincontri G, Southwood M, Sawiak SJ, Morrell NW, Davenport AP, Maguire JJ, 2019
Elabela/Toddler Is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary arterial hypertension., Yang P, Read C, Kuc RE, Buonincontri G, Southwood M, Torella R, Upton PD, Crosby A, Sawiak SJ, Carpenter TA, Glen RC, Morrell NW, Maguire JJ, Davenport AP, 2017
[Pyr1]Apelin(1-12) is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr1]Apelin-13., Yang P, Kuc RE, Brame AL, Dyson A, Singer M, Glen RC, Cheriyan J, Wilkinson IB, Davenport AP, Maguire JJ, 2017
Cardiac action of the first G protein biased small molecule apelin agonist., Read C, Fitzpatrick CM, Yang P, Kuc RE, Maguire JJ, Glen RC, Foster RE, Davenport AP, 2016
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. (Review), Yang P, Maguire JJ, Davenport AP, 2015

肺动脉高压尘肺病慢性阻塞性肺病分子机制病理生理学干预策略新靶点临床前实验转化研究多学科合作

战军 - 北京大学

Area of Focus
肿瘤 | 转移 | 耐药 | 分子机制 | 转化研究 | 癌症 | 化疗 | 诊断 | 预后 | Kindlin-2

何林 - 北京大学

王泽芬 - 武汉大学

Area of Focus
免疫学 | 微环境 | 大脑 | 损伤 | 胶质瘤 | 病理生理学 | 神经保护 | 细胞激活 | 炎症 | 分子机制

View All

Personal Information

Academic Information

Research

联系我们

还未创建账户?

Personal Information

Academic Information

Research

联系我们