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Xuezhu Feng
Life Science
University of Science and Technology of China
Anhui
Language: English, Chinese
Rna Expression
Rna Processing
Eukaryotic Cells
Transcriptional Regulation
Non-Coding Rna
Pluripotent Stem Cells
Biological Functions
Gene Expression
Molecular Biology
Cellular Biology
Areas of Focus
- Regulation of RNA expression and processing in eukaryotic cells
- Transcriptional regulation mechanisms in eukaryotes
- Expression and regulation mechanisms of non-coding RNA in human pluripotent stem cells and their biological functions
Work Experience
- 1999-2001 - Lecturer: Beijing Medical University, Department of Embryology
- 2007-2014 - Senior Scientist: Cellular Dynamics International Inc.
- 2014-present - Special Researcher: University of Science and Technology of China, School of Life Sciences
Academic Background & Achievements
- 1999 - Bachelor's degree in Clinical Medicine: Beijing Medical University
- 2007 - PhD in Molecular and Cellular Biology: University of Wisconsin-Madison
Publications
- Functional Proteomics Identifies a PICS Complex Required for piRNA Maturation and Chromosome Segregation, Chenming Zeng, Chenchun Weng, Xiaoyang Wang, Yong-Hong Yan, Wen-Jun Li, Demin Xu, Minjie Hong, Shanhui Liao, Meng-Qiu Dong, Xuezhu Feng, Chao Xu, Shouhong Guang, 2019
- The USTC complex co-opts an ancient machinery to drive piRNA transcription in C. elegans, Chenchun Weng, Joanna Kosalka, Ahmet C. Berkyurek, Przemyslaw Stempor, Xuezhu Feng, Hui Mao, Chenming Zeng, Wen-Jun Li, Yong-Hong Yan, Meng-Qiu Dong, Natalia Rosalía Morero, Cecilia Zuliani, Orsolya Barabas, Julie Ahringer, Shouhong Guang, Eric A. Miska, 2018
- Erroneous ribosomal RNAs promote the generation of antisense ribosomal siRNA, Chengming Zhu, Qi Yan, Chenchun Weng, Xinhao Hou, Hui Mao, Dun Liu, Xuezhu Feng, Shouhong Guang, 2018
- A cytoplasmic Argonaute protein promotes the inheritance of RNAi, Fei Xu, Xuezhu Feng, Xiangyang Chen, Chenchun Weng, Qi Yan, Ting Xu, Minjie Hong, Shouhong Guang, 2018
- RNA-dependent RNA polymerases-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway in C. elegans, Xufei Zhou, Xuezhu Feng, Hui Mao, Mu Li, Fei Xu, Kai Hu, Shouhong Guang, 2017
- The Nrde pathway mediates small RNA-directed histone H3 lysine 27 trimethylation in Caenorhabditis elegans, Hui Mao, Chengming Zhu, Dandan Zong, Chenchun Weng, Xiangwei Yang, Hui Huang, Dun Liu, Xuezhu Feng, Shouhong Guang, 2015
- Targeted Chromosomal Rearrangements via a Combinatorial Use of CRISPR/Cas9 and Cre/LoxP Technologies in Caenorhabditis elegans, Chen X, Liao S, Huang X, Xu T, Feng X, Guang S, 2018
- Targeted Chromosomal Translocations and Essential Gene Knockout Using CRISPR/Cas9 Technology in Caenorhabditis elegans, Xiangyang Chen, Mu Li, Xuezhu Feng, Shouhong Guang, 2015
- Nuclear RNAi Contributes to the Silencing of Off-Target Genes and Repetitive Sequences in Caenorhabditis elegans, Zhou X, Xu F, Mao H, Ji J, Meng Y, Feng X, Guang S, 2014
- Protein kinase C mediated extraembryonic endoderm differentiation of human embryonic stem cells, Feng X, Zhang J, Smuga-Otto K, Tian S, Yu J, Stewart R, Thomson JA, 2012
- Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes, Matthew E. Brown, Elizabeth Rondon, Deepika Rajesh, Amanda Mack, Rachel Lewis, Xuezhu Feng, Laura Jo Zitur, Randall D. Learish, Emile F. Nuwaysir, 2010
- Mass spectrometry identifies and quantifies 74 unique histone H4 isoforms in differentiating human embryonic stem cells, Phanstiel D, Brumbaugh J, Berggren WT, Conard K, Feng X, Levenstein ME, McAlister GC, Thomson JA, Coon JJ, 2008
- Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells, Xu RH, Peck RM, Li DS, Feng X, Ludwig T, Thomson JA, 2005
