Professor | Daxing Gao | Asia Growth Partners

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Name	Daxing Gao
Contact Information	daxing@ustc.edu.cn
Language ability	English, Chinese
Province	Anhui

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Name

Daxing Gao

Contact Information

daxing@ustc.edu.cn

Language ability

English, Chinese

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Basic Medical Sciences
Academic Background & Achievements	2006-2010 Bachelor: University of Science and Technology of China 2010-2015 PhD in Immunology: University of Texas Southwestern Medical Center 2018 Revson Fellowship
Work Experience	2016-2019 Postdoctoral Research: Rockefeller University 2019-present Professor: University of Science and Technology of China
Awards	2014 Chinese Government Award for Outstanding Self-financed Students Abroad 2014 American Association of Immunologists Young Investigator Award 2015 Streilein Chair Freedom Award

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Basic Medical Sciences

Academic Background & Achievements

2006-2010 Bachelor: University of Science and Technology of China
2010-2015 PhD in Immunology: University of Texas Southwestern Medical Center
2018 Revson Fellowship

Work Experience

2016-2019 Postdoctoral Research: Rockefeller University
2019-present Professor: University of Science and Technology of China

Awards

2014 Chinese Government Award for Outstanding Self-financed Students Abroad
2014 American Association of Immunologists Young Investigator Award
2015 Streilein Chair Freedom Award

Areas of Focus	Antiviral innate immunity mechanisms Role of innate immune signaling in auto-inflammation Development of novel tumor treatment strategies
Publications	cGAS-activated endothelial cell-T cell cross-talk initiates tertiary lymphoid structure formation, R. Zhao, J. Zhang, J. Ma, Y. Qu, Z. Yang, Z. Yin, F. Li, Z. Dong, Q. Sun, S. Zhu, Z. J. Chen, D. Gao, 2024 Human DBR1 deficiency impairs stress granule-dependent PKR antiviral immunity, Shuo Ru, Sisi Tang, Hui Xu, Jiahao Yin, Yan Guo, Liuping Song, Zhenyu Jin, Danyel Lee, Yi-Hao Chan, Xingyao Chen, Luke Buerer, William Fairbrother, Weidong Jia, Jean-Laurent Casanova, Shen-Ying Zhang, Daxing Gao, 2024 SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency, Y.-H. Chan, V. Lundberg, J. Le Pen, J. Yuan, D. Lee, F. Pinci, S. Volpi, K. Nakajima, V. Bondet, S. Åkesson, N. V. Khobrekar, A. Bodansky, L. Du, T. Melander, A.-A. Mariaggi, Y. Seeleuthner, T. S. Saleh, D. Chakravarty, P. Marits, K. Dobbs, S. Vonlanthen, V. Hennings, K. Thörn, D. Rinchai, L. Bizien, M. Chaldebas, A. Sobh, T. Özçelik, S. Keles, S. A. AlKhater, C. Prando, I. Meyts, COVID Human Genetic Effort, M. R. Wilson, J. Rosain, E. Jouanguy, M. Aubart, L. Abel, T. H. Mogensen, Q. Pan-Hammarström, D. Gao, D. Duffy, A. Cobat, S. Berg, L. D. Notarangelo, O. Harschnitz, C. M. Rice, L. Studer, J.-L. Casanova, O. Ekwall, S.-Y. Zhang, 2024 TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons, D. Gao, M. J. Ciancanelli, P. Zhang, O. Harschnitz, V. Bondet, M. Hasek, J. Chen, X. Mu, Y. Itan, A. Cobat, V. Sancho-Shimizu, B. Bigio, L. Lorenzo, G. Ciceri, J. McAlpine, E. Anguiano, E. Jouanguy, D. Chaussabel, I. Meyts, M. S. Diamond, L. Abel, S. Hur, G. A. Smith, L. Notarangelo, D. Duffy, L. Studer, J.-L. Casanova, S.-Y. Zhang, 2021 Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis, F. G. Lafaille, O. Harschnitz, Y. S. Lee, P. Zhang, M. L. Hasek, G. Kerner, Y. Itan, O. Ewaleifoh, F. Rapaport, T. M. Carlile, M. E. Carter-Timofte, D. Paquet, K. Dobbs, B. Zimmer, D. Gao, M. F. Rojas-Duran, D. Kwart, V. Rattina, M. J. Ciancanelli, J. L. McAlpine, L. Lorenzo, S. Boucherit, F. Rozenberg, R. Halwani, B. Henry, N. Amenzoui, Z. Alsum, L. Marques, J. A. Church, S. Al-Muhsen, M. Tardieu, A. A. Bousfiha, S. R. Paludan, T. H. Mogensen, L. Quintana-Murci, M. Tessier-Lavigne, G. A. Smith, L. D. Notarangelo, L. Studer, W. Gilbert, L. Abel, J. L. Casanova, S. Y. Zhang, 2019 Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases, D. Gao, T. Li, X.-D. Li, X. Chen, Q.-Z. Li, M. Wight-Carter, Z. J. Chen, 2015 Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses, D. Gao, J. Wu, Y. T. Wu, F. Du, C. Aroh, N. Yan, L. Sun, Z. J. Chen, 2013 Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects, X. D. Li, J. Wu, D. Gao, H. Wang, L. Sun, Z. J. Chen, 2013 Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins, D. Ma, A. Xie, J. Lv, X. Min, X. Zhang, Q. Zhou, D. Gao, E. Wang, L. Gao, L. Cheng, S. Liu, 2024

Areas of Focus

Antiviral innate immunity mechanisms
Role of innate immune signaling in auto-inflammation
Development of novel tumor treatment strategies

Publications

cGAS-activated endothelial cell-T cell cross-talk initiates tertiary lymphoid structure formation, R. Zhao, J. Zhang, J. Ma, Y. Qu, Z. Yang, Z. Yin, F. Li, Z. Dong, Q. Sun, S. Zhu, Z. J. Chen, D. Gao, 2024
Human DBR1 deficiency impairs stress granule-dependent PKR antiviral immunity, Shuo Ru, Sisi Tang, Hui Xu, Jiahao Yin, Yan Guo, Liuping Song, Zhenyu Jin, Danyel Lee, Yi-Hao Chan, Xingyao Chen, Luke Buerer, William Fairbrother, Weidong Jia, Jean-Laurent Casanova, Shen-Ying Zhang, Daxing Gao, 2024
SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency, Y.-H. Chan, V. Lundberg, J. Le Pen, J. Yuan, D. Lee, F. Pinci, S. Volpi, K. Nakajima, V. Bondet, S. Åkesson, N. V. Khobrekar, A. Bodansky, L. Du, T. Melander, A.-A. Mariaggi, Y. Seeleuthner, T. S. Saleh, D. Chakravarty, P. Marits, K. Dobbs, S. Vonlanthen, V. Hennings, K. Thörn, D. Rinchai, L. Bizien, M. Chaldebas, A. Sobh, T. Özçelik, S. Keles, S. A. AlKhater, C. Prando, I. Meyts, COVID Human Genetic Effort, M. R. Wilson, J. Rosain, E. Jouanguy, M. Aubart, L. Abel, T. H. Mogensen, Q. Pan-Hammarström, D. Gao, D. Duffy, A. Cobat, S. Berg, L. D. Notarangelo, O. Harschnitz, C. M. Rice, L. Studer, J.-L. Casanova, O. Ekwall, S.-Y. Zhang, 2024
TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons, D. Gao, M. J. Ciancanelli, P. Zhang, O. Harschnitz, V. Bondet, M. Hasek, J. Chen, X. Mu, Y. Itan, A. Cobat, V. Sancho-Shimizu, B. Bigio, L. Lorenzo, G. Ciceri, J. McAlpine, E. Anguiano, E. Jouanguy, D. Chaussabel, I. Meyts, M. S. Diamond, L. Abel, S. Hur, G. A. Smith, L. Notarangelo, D. Duffy, L. Studer, J.-L. Casanova, S.-Y. Zhang, 2021
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis, F. G. Lafaille, O. Harschnitz, Y. S. Lee, P. Zhang, M. L. Hasek, G. Kerner, Y. Itan, O. Ewaleifoh, F. Rapaport, T. M. Carlile, M. E. Carter-Timofte, D. Paquet, K. Dobbs, B. Zimmer, D. Gao, M. F. Rojas-Duran, D. Kwart, V. Rattina, M. J. Ciancanelli, J. L. McAlpine, L. Lorenzo, S. Boucherit, F. Rozenberg, R. Halwani, B. Henry, N. Amenzoui, Z. Alsum, L. Marques, J. A. Church, S. Al-Muhsen, M. Tardieu, A. A. Bousfiha, S. R. Paludan, T. H. Mogensen, L. Quintana-Murci, M. Tessier-Lavigne, G. A. Smith, L. D. Notarangelo, L. Studer, W. Gilbert, L. Abel, J. L. Casanova, S. Y. Zhang, 2019
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases, D. Gao, T. Li, X.-D. Li, X. Chen, Q.-Z. Li, M. Wight-Carter, Z. J. Chen, 2015
Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses, D. Gao, J. Wu, Y. T. Wu, F. Du, C. Aroh, N. Yan, L. Sun, Z. J. Chen, 2013
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects, X. D. Li, J. Wu, D. Gao, H. Wang, L. Sun, Z. J. Chen, 2013
Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins, D. Ma, A. Xie, J. Lv, X. Min, X. Zhang, Q. Zhou, D. Gao, E. Wang, L. Gao, L. Cheng, S. Liu, 2024

Antiviral Innate Immunity Mechanisms Auto-Inflammation Immune Signaling Tumor Treatment Strategies Novel Development

Fuping You - Peking University

Dan Lu - Peking University

Tao Li - Fudan University

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