Areas of Focus
- Development of more efficient and higher resolution cryo-EM methodologies
- Molecular mechanisms and regulation of nucleic acid quality control
- Coordination mechanisms of cytoskeleton and biomembrane systems
Work Experience
- 2001-2006 - Lawrence Berkeley National Laboratory, Life Sciences Division - Postdoctoral Researcher
- 2006-2008 - Lawrence Berkeley National Laboratory, Life Sciences Division - Research Scientist
- 2009-2011 - Yale University, Department of Molecular Biophysics and Biochemistry - Tenure-Track Assistant Professor
- 2010.12-present - Tsinghua University, School of Life Sciences - Professor, Doctoral Supervisor
Academic Background & Achievements
- 1992-1996 Bachelor: Department of Biological Sciences and Technology, Tsinghua University
- 1996-2001 PhD: Department of Biological Sciences and Technology, Tsinghua University
- Dean of the School of Life Sciences, Tsinghua University (2016.04-2021.04)
Publications
- Structural insights into the mechanism of GTP initiation of microtubule assembly, Zhou J, Wang A, Song Y, Liu N, Wang J, Li Y, Liang X, Li GH, Chu HY, Wang HW*, 2023
- Dual-Affinity Graphene Sheets for High-Resolution Cryo-Electron Microscopy, Cheng H, Zheng LM, Liu N, Huang CY, Xu J, Lu Y, Cui XY, Xu K, Hou Y, Tang JC, Zhang Z, Li J, Ni XD, Chen YN*, Peng HL*, Wang HW*, 2023
- In situ structure of the red algal phycobilisome–PSII–PSI–LHC megacomplex, You X, Zhang X, Cheng J, Xiao YN, Ma JF, Sun S, Zhang XZ*, Wang HW*, Sui SF*, 2023
- Uniform thin ice on ultraflat graphene for high-resolution cryo-EM, Zheng LM, Liu N*, Gao XY, Zhu WQ, Liu K, Wu C, Yan R, Zhang JC, Gao X, Yao YT, Deng B, Xu J, Lu Y, Liu, ZM, Li MS, Wei XD*, Wang HW*, Peng HL*, 2023
- Functionalized graphene grids with various charges for single-particle cryo-EM, Lu Y, Liu N*, Liu Y, Zheng LM, Yang JH, Wang J, Jia X, Zi QR, Peng HL*, Rao Y*, Wang HW*, 2022
- Structural insights into dsRNA processing by Drosophila Dicer-2-Loqs-PD, Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li XM, Huang Y, Wang HW*, Ma JB*, 2022
- Atomically Thin Bilayer Janus Membranes for Cryo-electron Microscopy, Zheng L, Liu N, Liu Y, Li N, Zhang J, Wang C, Zhu W, Chen Y, Ying D, Xu J, Yang Z, Gao X, Tang J, Wang X, Liang Z, Zou R, Li Y, Gao P, Wei X*, Wang HW*, Peng HL*, 2021
- Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM, Liu N, Zheng LM, Xu J, Wang J, Hu CX, Lan J, Zhang X, Zhang J, Xu K, Cheng H, Yang Z, Gao X, Wang X, Peng HL*, Chen YN*, Wang HW*, 2021
- Structural Basis for pri-miRNA Recognition by Drosha, Jin W, Wang J, Liu CP, Wang HW*, Xu RM*, 2020
- Robust ultraclean atomically thin membranes for atomic-resolution electron microscopy, Zheng L, Chen Y, Li N, Zhang J, Liu N, Liu J, Dang W, Deng B, Li Y, Gao X, Tan C, Yang Z, Xu S, Wang M, Yang H, Sun L, Cui Y, Wei X, Gao P*, Wang HW*, Peng H*, 2020
- Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution, Fan X, Wang J, Zhang X, Yang Z, Zhang JC, Zhao L, Peng HL, Lei J*, Wang HW*, 2019
- Bioactive Functionalized Monolayer Graphene for High-Resolution Cryo-Electron Microscopy, Liu N, Zhang J, Chen Y*, Liu C, Zhang X, Xu K, Wen J, Luo Z, Chen S, Gao P, Jia K, Liu Z, Peng H*, Wang HW*, 2019
- Ligand-triggered allosteric ADP release primes a plant NLR complex, Wang J, Wang J, Hu M, Wu S, Qi J, Wang G, Han Z, Qi Y, Gao N, Wang HW*, Zhou JM*, Chai J*, 2019
- Reconstitution and structure of a plant NLR resistosome conferring immunity, Wang J, Hu M, Wang J, Qi J, Han Z, Wang G, Qi Y, Wang HW*, Zhou JM*, Chai J*, 2019
- Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate, Wang J, Wang J, Cheng H, Ke X, Sun L, Zhang Q, Wang HW*, 2018
