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Yangyang Shao
Life Science
Zhejiang University
Zhejiang
Language: English, Chinese
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Synthetic Biology Eukaryotic Chromosome Artificial Design New Function Research Dna Cloning Dna Delivery Crispr/Cas9 Genome Editing Yeast Cells Biomedical Applications
Areas of Focus
  • Synthetic Biology
  • Eukaryotic Chromosome Artificial Design and New Function Research
  • Development of New Technologies for Mega Base DNA Cloning and Delivery
Work Experience
  • 2021-present: Researcher and Group Leader at Zhejiang University, School of Life Sciences
  • 2021: Assistant Researcher at CAS Center for Excellence in Molecular Plant Sciences
  • 2018-2021: Postdoctoral Fellow at CAS Center for Excellence in Molecular Plant Sciences
  • 2011-2017: PhD Candidate at Shanghai Institute for Biological Sciences, CAS
Academic Background & Achievements
  • 2011-2017: PhD in Microbiology, Shanghai Institute for Biological Sciences, CAS
  • Published as first author in journals like Nature, Nature Protocols, and Cell Research
  • Selected achievements include 'Top Ten Scientific Advances in China' and 'Top Ten Advances in Life Sciences in China'
Publications
  • Creating a functional single chromosome yeast, Yangyang Shao et al., 2018
  • A single circular chromosome yeast, Yangyang Shao et al., 2019
  • Creating functional chromosome fusions in yeast with CRISPR–Cas9, Yangyang Shao et al., 2019
  • CRISPR-Cas9 facilitated multiple-chromosome fusion in Saccharomyces cerevisiae, Yangyang Shao et al., 2018
  • MEGA (Multiple Essential Genes Assembling) Deletion and Replacement Method for Genome Reduction in Escherichia coli, Xiaoli Xue et al., 2015
  • Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusions, Zhi-Jing Wu et al., 2020
Awards
  • Multiple awards and grants including Young Talent Support Plan, Zhejiang Outstanding Youth Fund
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