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Yingying Pu
Immunology and Metabolion
Wuhan University
Hubei
Language: Chinese, English
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Pathogens Biology Bacteria Resistance Infection Immunity Antibiotics Therapy Molecular Biology Biotechnology
Areas of Focus
  • Pathogen Biology
  • Bacterial Resistance
  • Bacterial Infection and Immunity
Work Experience
  • 2011 - 2015 Postdoctoral Researcher at BIOPIC, Peking University
  • 2012 - 2012 Visiting Scholar at Department of Chemistry and Chemical Biology, Harvard University
  • 2015 - 2018 Assistant Researcher at BIOPIC, Peking University
  • 2019 - Present Professor at Medical Research Institute/Center for Advanced Studies in Immunology and Metabolism, Wuhan University
  • 2019 - Present Adjunct Professor at Wuhan University Dental Hospital
Academic Background & Achievements
  • 2001 - 2005 Bachelor in Biotechnology: Shanghai Jiao Tong University
  • 2005 - 2011 PhD in Biotechnology: Peking University
Publications
  • Combatting persister cells: The daunting task in post-antibiotics era, Zhou, Y., Liao, H., Pei, L., and Pu, Y*, 2023
  • Nanoparticles Promote Bacterial Antibiotic Tolerance via Inducing Hyperosmotic Stress Response, Zhang P, Qiu Y, Wang Y, Xiao Y, Yu S, Shi M, Ni Y, Miron R J, Pu Y*, Zhang Y*, 2022
  • Photothermal Therapy may be a Double-edge Sword by Inducing the Formation of Bacterial Antibiotic Tolerance, Qiu Y, Yu S, Wang Y, Xiao L, Pei L, Pu Y*, Zhang Y*, 2022
  • Genomic and Transcriptomic Profiling of Hepatoid Adenocarcinoma of the Stomach, Liu Z, Wang A, Pu Y, Li Z, Xue D, Zhang C, Xiang X, E J, Bu Z, Bai F & Ji J, 2021
  • Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p, Tong, Y., Zhang, J., Sun, N., Wang, X., Wei, Q., Zhang, Y., Huang, R., Pu, Y., Dai, H., Ren, B., Pei, G., Song, F., Zhu, G., Wang, X., Xia, X., Chen, X., Jiang, L., Zhang, J., Ouyang, L., Zhang, B., Jiang, Y., Liu, X., Calderone, R., Bai, F.*, Zhang, L.*, Alterovitz, G, 2021
  • A General Workflow for Characterization of Nernstian Dyes and Their Effects on Bacterial Physiology, Mancini L, Terradot G, Tian T, Pu Y, Li Y, Lo C, Bai F and Pilizota T, 2020
  • ATP-dependent dynamic protein aggregation regulates bacterial dormancy depth critical for antibiotic tolerance, Pu Y, Li Y, Bai F, et al., 2019
  • Active efflux in dormant bacterial cells - New insights into antibiotic persistence, Pu Y, Ke Y, Bai F, 2017
  • Rice Dwarf Virus P2 Protein Hijacks Auxin Signaling by Directly Targeting the Rice OsIAA10 Protein, Enhancing Viral Infection and Disease Development, Jin L, Qin Q, Wang Y, Pu Y, Li Y, et al., 2017
  • Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells, Pu Y, Zhao Z, Li Y, Bai F, Xie X, et al., 2016
  • Real Time Visualization of Perylene Nano-clusters (PNCs) in Water and Their Partitioning to Graphene Surface and Macrophage Cells, Guo X, Jin X, Lv X, Pu Y, Bai F*, 2015
  • Bacterial Persistence, Liu Y, Yang J, Zhao Z, Pu Y*, Bai F*, 2014
  • Rice dwarf viruses with dysfunctional genomes generated in plants are filtered out in vector insects -implications for the virus origin, Pu Y, Kikuchi A, Moriyasu Y, Tomara M, Jin Y, Suga H, Wei T, Li Y, Omura T, 2011
  • Crystal Structure and Octamerization of the Viroplasm Matrix Protein P9-1 of Rice Black Streaked Dwarf Virus, Akita F, Higashiura A, Shimizi T, Pu Y, Suzuki M, Ichiki T, Sasaya T, Kanamaru S, Arisaka F, Tsukihara T, Nakagawa A, Omura T, 2012
  • The P2 capsid protein of the nonenveloped rice dwarf phytoreovirus induces membrane fusionin insect host cells, Zhou F, Pu Y, Wei T, Liu H, Deng W, Wei CH, Ding B, Omura T, Li Y, 2007
  • Interaction of rice dwarf virus outer capsid P8 protein with rice glycolate oxidase mediates relocalization of P8, Zhou F, Wu G, Deng W, Pu Y, Wei C, Li Y, 2007
Awards
  • 2021: Youth Top-notch Talent by the Organization Department of the Central Committee
  • 2021: Chutian Scholar Distinguished Professor, Hubei Province
  • 2022: Hubei Province Outstanding Youth Project
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