Professor | Linquan Bai | Asia Growth Partners

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Name	Linquan Bai
Contact Information	bailq@sjtu.edu.cn
Language ability	English, Chinese, German
Province	Shanghai

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Name

Linquan Bai

Contact Information

bailq@sjtu.edu.cn

Language ability

English, Chinese, German

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	1992 Bachelor of Science in Microbiology, Shandong University 1995 Master of Science in Microbiology, Huazhong Agricultural University 1998 Doctor of Science in Molecular Biology, Huazhong Agricultural University
Work Experience	1999-2002 Postdoctoral Researcher, Department of Chemistry, University of Washington, USA 2006-2007 Research on biosynthetic regulation at the Microbiology Institute, University of Tuebingen, Germany
Awards	2006 Top Ten Scientific and Technological Progress in Chinese Universities 2007 Second Prize of Natural Science, Ministry of Education 2008 Second Prize of National Natural Science

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

1992 Bachelor of Science in Microbiology, Shandong University
1995 Master of Science in Microbiology, Huazhong Agricultural University
1998 Doctor of Science in Molecular Biology, Huazhong Agricultural University

Work Experience

1999-2002 Postdoctoral Researcher, Department of Chemistry, University of Washington, USA
2006-2007 Research on biosynthetic regulation at the Microbiology Institute, University of Tuebingen, Germany

Awards

2006 Top Ten Scientific and Technological Progress in Chinese Universities
2007 Second Prize of Natural Science, Ministry of Education
2008 Second Prize of National Natural Science

Areas of Focus	Biosynthesis of Jinggangmycin/Validamycin Biosynthetic mechanisms and combinatorial biosynthesis of ansamycin antibiotics Bioprospecting of secondary metabolite biosynthetic gene resources Research on the rice sheath blight antibiotic Jinggangmycin
Publications	Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis, Zheng L, Zhou X, Zhang H, Ji X, Li L, Huang L, Bai L, Zhang H, 2012 Unveiling the biosynthetic puzzle of destruxins in Metarhizium species, Wang B, Kang Q, Lu Y, Bai L, Wang C, 2012 Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis, Li Y, Zhao P, Kang Q, Ma J, Bai L, Deng Z, 2011 Biosynthesis of 3,5-AHBA-derived natural products, Kang Q, Shen Y, Bai L, 2012 Cloning and characterization of the polyether salinomycin biosynthesis gene cluster of Streptomyces albus XM211, Jiang C, Wang H, Kang Q, Liu J, Bai L, 2012 Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008, Zhou X, Wu H, Li Z, Zhou X, Bai L, Deng Z, 2011 Toward steadfast growth of antibiotic research in China: From natural products to engineered biosynthesis, Kang Q, Bai L, Deng Z, 2011 Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis, Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L, Deng Z, 2011 N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis, Wu Y, Kang Q, Shen Y, Su W, Bai L, Floss HG, 2011 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS, Wu Y, Kang Q, Shen Y, Su W, Bai L, 2011

Areas of Focus

Biosynthesis of Jinggangmycin/Validamycin
Biosynthetic mechanisms and combinatorial biosynthesis of ansamycin antibiotics
Bioprospecting of secondary metabolite biosynthetic gene resources
Research on the rice sheath blight antibiotic Jinggangmycin

Publications

Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis, Zheng L, Zhou X, Zhang H, Ji X, Li L, Huang L, Bai L*, Zhang H*, 2012
Unveiling the biosynthetic puzzle of destruxins in Metarhizium species, Wang B, Kang Q, Lu Y, Bai L, Wang C, 2012
Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis, Li Y, Zhao P, Kang Q, Ma J, Bai L*, Deng Z, 2011
Biosynthesis of 3,5-AHBA-derived natural products, Kang Q, Shen Y, Bai L*, 2012
Cloning and characterization of the polyether salinomycin biosynthesis gene cluster of Streptomyces albus XM211, Jiang C, Wang H, Kang Q, Liu J, Bai L*, 2012
Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008, Zhou X, Wu H, Li Z, Zhou X, Bai L*, Deng Z, 2011
Toward steadfast growth of antibiotic research in China: From natural products to engineered biosynthesis, Kang Q, Bai L*, Deng Z, 2011
Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis, Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L*, Deng Z, 2011
N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis, Wu Y, Kang Q, Shen Y, Su W, Bai L*, Floss HG, 2011
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS, Wu Y, Kang Q, Shen Y, Su W, Bai L*, 2011

Biosynthesis Jinggangmycin Validamycin Ansamycin Antibiotics Bioprospecting Gene Resources Secondary Metabolites Rice Sheath Blight Antibiotic Research

Yinhua Lu - Shanghai Normal University

Hua Yuan - Shanghai Normal University

Shuangjun Lin - Shanghai Jiao Tong University

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