Professor | Li Fuzhuo | Asia Growth Partners

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Name	Li Fuzhuo
Contact Information	lifuzhuo@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Li Fuzhuo

Contact Information

lifuzhuo@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	2012-2017 Ph.D. in Chemistry: Peking University 2008-2012 B.Sc. in Chemistry: Lanzhou University
Work Experience	2022-present - Fudan University - Junior Researcher 2017-2022 - Scripps Research Institute - Postdoctoral Researcher
Awards	National Overseas High-Level Talent Introduction Youth Project (2024-2027) Shanghai Overseas High-Level Talent Introduction Program

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

2012-2017 Ph.D. in Chemistry: Peking University
2008-2012 B.Sc. in Chemistry: Lanzhou University

Work Experience

2022-present - Fudan University - Junior Researcher
2017-2022 - Scripps Research Institute - Postdoctoral Researcher

Awards

National Overseas High-Level Talent Introduction Youth Project (2024-2027)
Shanghai Overseas High-Level Talent Introduction Program

Areas of Focus	Directed evolution of proteins and development of novel enzymatic catalytic methodologies Application of chemoenzymatic strategies in the synthesis of bioactive natural products and chiral drugs Structure-activity relationship and mechanism of action studies of bioactive natural products
Publications	Chemoenzymatic Approaches for Exploring Structure–Activity Relationship Studies of Bioactive Natural Products, Li, F.; Deng, H.; Renata, H., 2023 Remote B-Ring Oxidation of Sclareol with an Engineered P450 Facilitates Divergent Access to Complex Terpenoids, Li, F.; Deng, H.; Renata, H., 2022 A Chiral-Pool-Based Strategy to Access Trans-Syn-Fused Drimane Meroterpenoids: Chemoenzymatic Total Syntheses of Polysin, N-Acetyl-Polyveoline and the Chrodrimanins, Li, F.; Renata, H., 2021 Stereoselective Synthesis of β-Branched α-Amino Acids via a Biocatalytic Dynamic Kinetic Resolution, Li, F.; Yang, L.-C.; Zhang, J.; Chen. J. S.; Renata, H., 2021 Merging Chemoenzymatic and Radical-Based Retrosynthetic Logic for Rapid and Modular Synthesis of Oxidized Meroterpenoids, Li, J.; Li, F.; King-Smith, E.; Renata, H., 2020 Enzymatic C–H Functionalizations for Natural Product Synthesis, Li, F.; Zhang, X.; Renata, H., 2019 Bioinspired Asymmetric Synthesis of Hispidanin A, Li, F.; Tu, Q.; Chen. S.; Zhu, L.; Lan, Y.; Gong, J.; Yang, Z., 2017 A Chiral Pool Approach for Asymmetric Syntheses of (-)-Antrocin, (+)-Asperolide C and (-)-trans-Ozic acid, Li, F.; Li, S.; Zhang, P.; Huang, Z.; Zhang, W.; Gong, J.-X.; Yang Z., 2016 Palladium-Catalyzed Carbonylative Cyclization of Aryl Alkenes/Alkenols: A New Reaction Mode for the Synthesis of Electron-Rich Chromanes, Li, S.; Li, F.; Gong, J.; Yang. Z., 2015 Asymmetric Total Synthesis of (-)-Maoecrystal V, Zhang, W.; Shao, W.; Li, F.; Gong, J., 2015 Collective Synthesis of Humulanolides Using a Metathesis Cascade Reaction, Han, J.; Li, F.; Li, C.-C., 2014 牛樟芝素的制备方法, 李付琸; 张伟滨; 张鹏鹏; 黄智辉; 龚建贤; 曾耀铭; 杨震, 2017

Areas of Focus

Directed evolution of proteins and development of novel enzymatic catalytic methodologies
Application of chemoenzymatic strategies in the synthesis of bioactive natural products and chiral drugs
Structure-activity relationship and mechanism of action studies of bioactive natural products

Publications

Chemoenzymatic Approaches for Exploring Structure–Activity Relationship Studies of Bioactive Natural Products, Li, F.; Deng, H.; Renata, H., 2023
Remote B-Ring Oxidation of Sclareol with an Engineered P450 Facilitates Divergent Access to Complex Terpenoids, Li, F.; Deng, H.; Renata, H., 2022
A Chiral-Pool-Based Strategy to Access Trans-Syn-Fused Drimane Meroterpenoids: Chemoenzymatic Total Syntheses of Polysin, N-Acetyl-Polyveoline and the Chrodrimanins, Li, F.; Renata, H., 2021
Stereoselective Synthesis of β-Branched α-Amino Acids via a Biocatalytic Dynamic Kinetic Resolution, Li, F.; Yang, L.-C.; Zhang, J.; Chen. J. S.; Renata, H., 2021
Merging Chemoenzymatic and Radical-Based Retrosynthetic Logic for Rapid and Modular Synthesis of Oxidized Meroterpenoids, Li, J.; Li, F.; King-Smith, E.; Renata, H., 2020
Enzymatic C–H Functionalizations for Natural Product Synthesis, Li, F.; Zhang, X.; Renata, H., 2019
Bioinspired Asymmetric Synthesis of Hispidanin A, Li, F.; Tu, Q.; Chen. S.; Zhu, L.; Lan, Y.; Gong, J.; Yang, Z., 2017
A Chiral Pool Approach for Asymmetric Syntheses of (-)-Antrocin, (+)-Asperolide C and (-)-trans-Ozic acid, Li, F.; Li, S.; Zhang, P.; Huang, Z.; Zhang, W.; Gong, J.-X.; Yang Z., 2016
Palladium-Catalyzed Carbonylative Cyclization of Aryl Alkenes/Alkenols: A New Reaction Mode for the Synthesis of Electron-Rich Chromanes, Li, S.; Li, F.; Gong, J.; Yang. Z., 2015
Asymmetric Total Synthesis of (-)-Maoecrystal V, Zhang, W.; Shao, W.; Li, F.; Gong, J., 2015
Collective Synthesis of Humulanolides Using a Metathesis Cascade Reaction, Han, J.; Li, F.; Li, C.-C., 2014
牛樟芝素的制备方法, 李付琸; 张伟滨; 张鹏鹏; 黄智辉; 龚建贤; 曾耀铭; 杨震, 2017

Protein Evolution Enzymatic Catalysis Chemoenzymatic Synthesis Bioactive Natural Products Chiral Drugs Structure-Activity Relationship Mechanism Of Action Green Chemistry Synthetic Biology Biocatalysis

Hongbin Zou - Zhejiang University

Lianli Sun - Zhejiang University

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