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Yan You
Pharmaceutical Sciences
Fudan University
Shanghai
Language: Chinese, English
Metabolic Diseases
Immune Diseases
Pathological Mechanisms
Key Targets
Endosome
Lysosome
Signal Regulation
Drug Screening
Molecular Pharmacology
Research
Areas of Focus
- Pathological mechanisms and key target discovery of metabolic immune diseases
- Signal regulation of endosome/lysosome pathway
- Targeted drug screening and molecular pharmacology mechanism research
Work Experience
- 2018.9-2021.4 - National Institutes of Health (NIH) - Postdoctoral Researcher
- 2021.5-Present - Fudan University School of Pharmacy - Associate Researcher
Academic Background & Achievements
- 2008.9-2012.6 Bachelor's Degree: Lanzhou University
- 2012.9-2015.6 Master's Degree: Sun Yat-sen University
- 2015.9-2018.6 Ph.D.: Fudan University
Publications
- Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-dependent TFEB Signaling Pathway, You Y, Bao WL, Zhang S, et al., 2020
- Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation, Bao W*, Liu X*, You Y*, et al., 2021
- A crisper-based method for testing the essentiality of a gene, You Y and Sharmila GR, 2020
- SNX10 deficiency restricts foam cell formation and protects against atherosclerosis by suppressing CD36-Lyn axis, Fan YJ, Yang JL and You Y#, 2020
- SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy, You Y, Li WZ, Zhang S, et al., 2018
- Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis, You Y, Zhou C, Li D, et al., 2016
- Deficiency of sorting nexin 10 prevents bone erosion in collagen induced mouse arthritis through promoting NFATc1 degradation, Zhou C, You Y, Zhu YZ, et al., 2016
Awards
- Shanghai Pharmaceutical Society 7th Pharmacology Youth Paper Presentation - Excellent Paper Second Prize (2018)
- Shanghai Pharmaceutical Society 5th Pharmacology Youth Paper Presentation - Excellent Paper Second Prize (2016)
