Professor | Yan You | Asia Growth Partners

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Name	Yan You
Contact Information	yyou@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Yan You

Contact Information

yyou@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	2008.9-2012.6 Bachelor's Degree: Lanzhou University 2012.9-2015.6 Master's Degree: Sun Yat-sen University 2015.9-2018.6 Ph.D.: Fudan University
Work Experience	2018.9-2021.4 - National Institutes of Health (NIH) - Postdoctoral Researcher 2021.5-Present - Fudan University School of Pharmacy - Associate Researcher
Awards	Shanghai Pharmaceutical Society 7th Pharmacology Youth Paper Presentation - Excellent Paper Second Prize (2018) Shanghai Pharmaceutical Society 5th Pharmacology Youth Paper Presentation - Excellent Paper Second Prize (2016)

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

2008.9-2012.6 Bachelor's Degree: Lanzhou University
2012.9-2015.6 Master's Degree: Sun Yat-sen University
2015.9-2018.6 Ph.D.: Fudan University

Work Experience

2018.9-2021.4 - National Institutes of Health (NIH) - Postdoctoral Researcher
2021.5-Present - Fudan University School of Pharmacy - Associate Researcher

Awards

Shanghai Pharmaceutical Society 7th Pharmacology Youth Paper Presentation - Excellent Paper Second Prize (2018)
Shanghai Pharmaceutical Society 5th Pharmacology Youth Paper Presentation - Excellent Paper Second Prize (2016)

Areas of Focus	Pathological mechanisms and key target discovery of metabolic immune diseases Signal regulation of endosome/lysosome pathway Targeted drug screening and molecular pharmacology mechanism research
Publications	Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-dependent TFEB Signaling Pathway, You Y, Bao WL, Zhang S, et al., 2020 Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation, Bao W, Liu X, You Y*, et al., 2021 A crisper-based method for testing the essentiality of a gene, You Y and Sharmila GR, 2020 SNX10 deficiency restricts foam cell formation and protects against atherosclerosis by suppressing CD36-Lyn axis, Fan YJ, Yang JL and You Y#, 2020 SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy, You Y, Li WZ, Zhang S, et al., 2018 Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis, You Y, Zhou C, Li D, et al., 2016 Deficiency of sorting nexin 10 prevents bone erosion in collagen induced mouse arthritis through promoting NFATc1 degradation, Zhou C, You Y, Zhu YZ, et al., 2016

Areas of Focus

Pathological mechanisms and key target discovery of metabolic immune diseases
Signal regulation of endosome/lysosome pathway
Targeted drug screening and molecular pharmacology mechanism research

Publications

Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-dependent TFEB Signaling Pathway, You Y, Bao WL, Zhang S, et al., 2020
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation, Bao W*, Liu X*, You Y*, et al., 2021
A crisper-based method for testing the essentiality of a gene, You Y and Sharmila GR, 2020
SNX10 deficiency restricts foam cell formation and protects against atherosclerosis by suppressing CD36-Lyn axis, Fan YJ, Yang JL and You Y#, 2020
SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy, You Y, Li WZ, Zhang S, et al., 2018
Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis, You Y, Zhou C, Li D, et al., 2016
Deficiency of sorting nexin 10 prevents bone erosion in collagen induced mouse arthritis through promoting NFATc1 degradation, Zhou C, You Y, Zhu YZ, et al., 2016

Metabolic Diseases Immune Diseases Pathological Mechanisms Key Targets Endosome Lysosome Signal Regulation Drug Screening Molecular Pharmacology Research

Huang Hai - Fudan University

Xiaoyan Shen - Fudan University

Xue-Mei Zhang - Fudan University

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