Areas of Focus
- 代谢免疫性疾病的病理机制与关键靶点发现
- 内体/溶酶体途径的信号调控
- 靶向药物筛选及分子药理机制研究
Work Experience
- 2018.9-2021.4 - 美国国立卫生研究院 - 博士后研究员
- 2021.5-至今 - 复旦大学药学院 - 青年副研究员
Academic Background & Achievements
- 2008.9-2012.6 本科学位: 兰州大学
- 2012.9-2015.6 硕士学位: 中山大学
- 2015.9-2018.6 博士学位: 复旦大学
Publications
- Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-dependent TFEB Signaling Pathway, You Y, Bao WL, Zhang S, et al., 2020
- Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation, Bao W*, Liu X*, You Y*, et al., 2021
- A crisper-based method for testing the essentiality of a gene, You Y and Sharmila GR, 2020
- SNX10 deficiency restricts foam cell formation and protects against atherosclerosis by suppressing CD36-Lyn axis, Fan YJ, Yang JL and You Y#, 2020
- SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy, You Y, Li WZ, Zhang S, et al., 2018
- Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis, You Y, Zhou C, Li D, et al., 2016
- Deficiency of sorting nexin 10 prevents bone erosion in collagen induced mouse arthritis through promoting NFATc1 degradation, Zhou C, You Y, Zhu YZ, et al., 2016
Awards
- 上海市药学会第七届药理学青年论文报告会 - 优秀论文二等奖 (2018)
- 上海市药学会第五届药理学青年论文报告会 - 优秀论文二等奖 (2016)