Professor | Zhuohao He | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Zhuohao He
Contact Information	hezh@sioc.ac.cn
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Zhuohao He

Contact Information

hezh@sioc.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2005-09--2012-01 Ph.D. in Science: Institute of Neuroscience, Chinese Academy of Sciences 2001-09--2005-07 Bachelor's in Science: Wuhan University
Work Experience	2019-09~Present - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Researcher 2018-03~2019-08 - University of Pennsylvania - Associate Researcher 2013-03~2018-02 - University of Pennsylvania - Postdoctoral Researcher 2012-01~2012-11 - Institute of Neuroscience, Chinese Academy of Sciences - Assistant Researcher
Awards	Youth Neuroscientist Paper Award, 2nd Prize, Chinese Neuroscience Society, 2021 AAIC2019, 2019 Cold Spring Harbor Asia, 1st Prize, 2012

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2005-09--2012-01 Ph.D. in Science: Institute of Neuroscience, Chinese Academy of Sciences
2001-09--2005-07 Bachelor's in Science: Wuhan University

Work Experience

2019-09~Present - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Researcher
2018-03~2019-08 - University of Pennsylvania - Associate Researcher
2013-03~2018-02 - University of Pennsylvania - Postdoctoral Researcher
2012-01~2012-11 - Institute of Neuroscience, Chinese Academy of Sciences - Assistant Researcher

Awards

Youth Neuroscientist Paper Award, 2nd Prize, Chinese Neuroscience Society, 2021
AAIC2019, 2019
Cold Spring Harbor Asia, 1st Prize, 2012

Areas of Focus	Pathogenesis and model construction of neurodegenerative diseases
Publications	MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons, 3rd Author, 2024 A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury, Corresponding Author, 2023 Editorial: Multimodal interventions in Alzheimer's disease: from basic research to clinical practice, Corresponding Author, 2023 Concomitant protein pathogenesis in Parkinson's disease and perspective mechanisms, Corresponding Author, 2023 Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation- induced pathology, 13th Author, 2022 SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation, 8th Author, 2021 Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo, 3rd Author, 2020 Modulating TRADD to restore cellular homeostasis and inhibit apoptosis, 21st Author, 2020 Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau, 9th Author, 2020 Transmission of tauopathy strains is independent of their isoform composition, Corresponding Author, 2020 Abeta Plaques Enhance Alzheimer Brain Tau Seeded Pathologies Via Facilitating Neuritic Plaque Tau Aggregation., 1st Author, 2018 TRPC Channel Downstream Signaling Cascades, Corresponding Author, 2017 Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice, 4th Author, 2016 Ca2+ signaling initiated by canonical transient receptor potential channels in dendritic development, 2nd Author, 2015 TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production, 5th Author, 2015 TRPC5 Channel Is the Mediator of Neurotrophin-3 in Regulating Dendritic Growth via CaMKIIα in Rat Hippocampal Neurons, 1st Author, 2012 Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma, 2nd Author, 2010 Targeting TRPC6 channels in oesophageal carcinoma growth. Expert opinion on therapeutic targets, 1st Author, 2010 Critical role of TRPC6 channels in G2 phase transition and the development of human oesophageal cancer, Not mentioned, 2009 TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway, 6th Author, 2008 Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain, 7th Author

Areas of Focus

Pathogenesis and model construction of neurodegenerative diseases

Publications

MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons, 3rd Author, 2024
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury, Corresponding Author, 2023
Editorial: Multimodal interventions in Alzheimer's disease: from basic research to clinical practice, Corresponding Author, 2023
Concomitant protein pathogenesis in Parkinson's disease and perspective mechanisms, Corresponding Author, 2023
Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation- induced pathology, 13th Author, 2022
SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation, 8th Author, 2021
Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo, 3rd Author, 2020
Modulating TRADD to restore cellular homeostasis and inhibit apoptosis, 21st Author, 2020
Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau, 9th Author, 2020
Transmission of tauopathy strains is independent of their isoform composition, Corresponding Author, 2020
Abeta Plaques Enhance Alzheimer Brain Tau Seeded Pathologies Via Facilitating Neuritic Plaque Tau Aggregation., 1st Author, 2018
TRPC Channel Downstream Signaling Cascades, Corresponding Author, 2017
Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice, 4th Author, 2016
Ca2+ signaling initiated by canonical transient receptor potential channels in dendritic development, 2nd Author, 2015
TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production, 5th Author, 2015
TRPC5 Channel Is the Mediator of Neurotrophin-3 in Regulating Dendritic Growth via CaMKIIα in Rat Hippocampal Neurons, 1st Author, 2012
Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma, 2nd Author, 2010
Targeting TRPC6 channels in oesophageal carcinoma growth. Expert opinion on therapeutic targets, 1st Author, 2010
Critical role of TRPC6 channels in G2 phase transition and the development of human oesophageal cancer, Not mentioned, 2009
TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway, 6th Author, 2008
Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain, 7th Author

Neurodegenerative Diseases Pathogenesis Model Construction Alzheimer'S Disease Neurodegeneration Tau Protein Neuronal Signaling Protein Aggregation Brain Injury Cell Biology

Yujun Hou - Tongji University

Gang Pei - Tongji University

Ru Zhang - Tongji University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us