Areas of Focus
- Identification and confirmation of new targets of active natural products
- Screening of active natural products based on drug targets and NMR technology
- Evaluation of the druggability of active natural products
Academic Background & Achievements
- 2003-09--2008-07 PhD: University of Science and Technology of China
- 1999-09--2003-06 Bachelor's: Sichuan University
Publications
- Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase, Liu, Jiangxin, Ren, Jian, Yang, Kun, Chen, Shuang, Yang, Xinni, Zhao, Qin-Shi, 2022
- Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism, Liu, Jiangxin; Wu, Xing-De; Li, Wenyan; Yuan, Zaifeng; Yang, Kun; Zhao, Qin-Shi, 2021
- Eleven undescribed alkaloids from the rhizomes of Sinomenium acutum and their IDO1 and TDO inhibitory activities, Bi, Ran; Yang, Xinni; Zhou, Haofeng; Peng Liyan; Liu, Jiangxin; Zhao Qin-Shi, 2022
- NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches, Yang Emily, Yoo Chan, Liu Jiangxin, Wang He, Cao Jun, Li Fay-Wei, Pryer Kathleen M., Sun Tai-ping, Weigel Detlef, Zhou Pei, Chen Meng, 2019
- Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum, Nuan Ning, Zhao Qiyu, Duan Zilei, Ji Mengyao, Xing Meichen, Zhu Tengyu, Mwangi James, Rong Mingqiang, Liu Jiangxin, Lai Ren, 2019
- A sodium channel inhibitor ISTX-I with a novel structure provides a new hint at the evolutionary link between two toxin folds, Rong, Mingqiang, Liu, Jiangxin, Zhang, Meilin, Wang, Gan, Zhao,Gang, Wang, Guodong, Zhang, Yaping, Hu, Kaifeng, Lai, Ren, 2016
- Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors, Shao, Li-Dong, Su, Jia, Ye, Baixin, Liu, Jiang-Xin, Zuo, Zhi-Li, Li, Yan, Wang, Yue-Ying, Xia, Chengfeng, Zhao, Qin-Shi, 2017
- Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat, Liu, Jiangxin; Fan, Shilong; Lee, Chul-Jin; Arno, L Greenleaf; Zhou, Pei, 2013
- Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa, Wojtaszek, Jessica, Liu, Jiangxin, Souza, Sanjay, Wang, Su, Xue, yaohua, Walker, Graham C, Zhou, Pei, 2013
- Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factor, Liu, Jiangxin; Zhang, Jiahai; Yang, Yinshan; Huang, Hongda; Shen, Weiqun; Hu, Qi; Wang, Xingsheng; Wu, Jihui; Shi, Yunyu, 2008
