Areas of Focus
- Targeted Anti-tumor Drug Research
- Novel Antibody-Drug Conjugates Research
Work Experience
- 2015-11~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
- 2008-10~2009-10 - University of Bern, Switzerland - Postdoctoral Researcher
- 2000-07~2015-10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Research Intern, Assistant Researcher, Associate Researcher
Academic Background & Achievements
- 2002-08--2007-05 Ph.D. in Science: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- 1996-09--2000-05 Bachelor's in Science: School of Pharmacy, Fudan University
Publications
- Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer., Oncotarget, 2016
- Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents, Eur. J. Med. Chem., 2016
- Ga(OTf)(3)-promoted synthesis of functionalized 2-carbonyl-imidazo[1,2-a]pyridines derived from ethyl alpha-benzotriazolyl-alpha-morpholinoacetate., Rsc Adv, 2015
- Discovery and optimization of 4,5-diarylisoxazoles as potent dual inhibitors of pyruvate dehydrogenase kinase and heat shock protein 90, J. Med. Chem., 2014
- An efficient synthesis of novel dibenzoxdiazepine-fused heterocycles through a multicomponent reaction, Rsc Adv., 2014
- Synthesis and biological evaluation of 6H-pyrido[2 ',1 ':2,3] imidazo[4,5-c] isoquinolin-5(6H)-ones as antimitotic agents and inhibitors of tubulin polymerization, Bioorgan Med Chem, 2014
