Professor | 孟韬 | 数字化转型顾问

Name

孟韬

Contact Information

tmeng@sibs.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2002-08--2007-05 理学博士: 中国科学院上海药物研究所 1996-09--2000-05 理学学士: 复旦大学药学院
Work Experience	2015-11~现在 - 中国科学院上海药物研究所 - 研究员 2008-10~2009-10 - 瑞士Bern大学 - 博士后 2000-07~2015-10 - 中国科学院上海药物研究所 - 研究实习员，助理研究员，副研究员

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

Work Experience

Areas of Focus	靶向抗肿瘤药物研究新型抗体偶联药物研究
Publications	Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer., Oncotarget, 2016 Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents, Eur. J. Med. Chem., 2016 Ga(OTf)(3)-promoted synthesis of functionalized 2-carbonyl-imidazo[1,2-a]pyridines derived from ethyl alpha-benzotriazolyl-alpha-morpholinoacetate., Rsc Adv, 2015 Discovery and optimization of 4,5-diarylisoxazoles as potent dual inhibitors of pyruvate dehydrogenase kinase and heat shock protein 90, J. Med. Chem., 2014 An efficient synthesis of novel dibenzoxdiazepine-fused heterocycles through a multicomponent reaction, Rsc Adv., 2014 Synthesis and biological evaluation of 6H-pyrido[2 ',1 ':2,3] imidazo[4,5-c] isoquinolin-5(6H)-ones as antimitotic agents and inhibitors of tubulin polymerization, Bioorgan Med Chem, 2014

Areas of Focus

靶向抗肿瘤药物研究
新型抗体偶联药物研究

Publications

Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer., Oncotarget, 2016
Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents, Eur. J. Med. Chem., 2016
Ga(OTf)(3)-promoted synthesis of functionalized 2-carbonyl-imidazo[1,2-a]pyridines derived from ethyl alpha-benzotriazolyl-alpha-morpholinoacetate., Rsc Adv, 2015
Discovery and optimization of 4,5-diarylisoxazoles as potent dual inhibitors of pyruvate dehydrogenase kinase and heat shock protein 90, J. Med. Chem., 2014
An efficient synthesis of novel dibenzoxdiazepine-fused heterocycles through a multicomponent reaction, Rsc Adv., 2014
Synthesis and biological evaluation of 6H-pyrido[2 ',1 ':2,3] imidazo[4,5-c] isoquinolin-5(6H)-ones as antimitotic agents and inhibitors of tubulin polymerization, Bioorgan Med Chem, 2014

靶向治疗抗肿瘤药物研究抗体-药物偶联物癌症治疗药理学化疗生物技术分子生物学肿瘤学

胡坚杨 - 南方科技大学

宋军伟 - 南方科技大学

张宝童 - 南方科技大学

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