Professor | Lin Wang | Asia Growth Partners

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Name	Lin Wang
Contact Information	linwang@ibms.pumc.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Lin Wang

Contact Information

linwang@ibms.pumc.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking Union Medical College
Faculty	Basic Medical Sciences
Academic Background & Achievements	2015 - PhD in Science: Zhejiang University Selected for National Youth Talent Program
Work Experience	2015-09 to 2017 - Beijing University of Technology - Research in single-cell mass spectrometry 2017 to 2021-11 - Princeton University - Postdoctoral Research 2021-11 to present - Chinese Academy of Medical Sciences & Peking Union Medical College - Researcher
Awards	Selected for National Youth Talent Program

University/Lab Affiliation and Title

Peking Union Medical College

Faculty

Basic Medical Sciences

Academic Background & Achievements

2015 - PhD in Science: Zhejiang University
Selected for National Youth Talent Program

Work Experience

2015-09 to 2017 - Beijing University of Technology - Research in single-cell mass spectrometry
2017 to 2021-11 - Princeton University - Postdoctoral Research
2021-11 to present - Chinese Academy of Medical Sciences & Peking Union Medical College - Researcher

Awards

Selected for National Youth Talent Program

Areas of Focus	Metabolomics and spatially resolved metabolic imaging Targeted quantitative metabolomics and untargeted metabolic analysis High-throughput multi-omics analysis based on population cohort biosamples
Publications	Gut bacterial nutrient preferences quantified in vivo, Zeng, X., Xing, X., Gupta, M., Keber, F. C., Lopez, J. G., Lee, Y. J., Roichman, A., Wang, L., Neinast, M. D., Donia, M. S., WÜhr, M., Jang, C., Rabinowitz, J. D., 2022 Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth, Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M., Lu, W., Davidson, S., Liang, G., Oh, T. G., Downes, M., Evans, R., Von Hoff, D., Guo, J. Y., Han, H., Rabinowitz, J. D., 2022 Spatially-resolved isotope tracing reveals tissue metabolic activity, Wang, L., Xing, X., Zeng, X. F., Jackson, S. R., TeSlaa, T., Wolff, J., Yang, L. F., McReynolds, M. R., Li, X., Rabinowitz, J. D., Davidson, S. M., 2022 Metabolite discovery through global annotation of untargeted metabolomics data, Chen, L., Lu, W., Wang, L., Xing, X., Chen, Z., Teng, X., Zeng, X., Muscarella, A. D., Shen, Y., Cowan, A., McReynolds, M. R., Kennedy, B. J., Lato, A. M., Campagna, S. R., Singh, M., Rabinowitz, J. D., 2021 Methionine synthase supports tumour tetrahydrogolate pools, Ghergurovich, J. M., Xu, X., Wang, J. Z., Yang, L., Ryseck, R., Wang, L., Rabinowitz, J. D., 2021 A genetic model of methionine restriction extends Drosophila health and lifespan, Parkhitko A. A., Wang, L., Filine, E., Jouandin, P., Leshchiner, D., Binari, R., Asara, J. M., Rabinowitz, J. D., Perrimon, N., 2021 The source of glycolytic intermediates in mammalian tissues, TeSlaa, T., Bartman, C. R., Jankowski, C., Zhang, Z., Xu, X., Xing, X., Wang, L., Lu, W., Hui, S., Rabinowitz, J. D., 2021 Metabolic excretion associated with nutrient growth dysregulation promotes the rapid evolution of an overt metabolic defect, Green, R., Wang, L., Hart, S. F. M., Lu, W., Shelding, D., Burton, J. C., Mi, H., Capel, A., Chen, H. A., Lin, A., Subramaniam, A. R., Rabinowitz, J. D., Shou, W., 2020 Quantitative fluxomics of circulating metabolites, Hui, S., Cowan, A. J., Zeng X., Yang, L., TeSlaa, T., Li, X., Bartman, C., Zhang, Z., Jang, C., Wang, L., Lu, W., Rojas, J., Baur, J., Rabinowitz, J. D., 2020 Sensitive bromine-labeled probe D-BPBr for simultaneous identification and quantification of chiral amino acids and amino containing metabolites profiling in human biofluid by HPLC/MS, Shen, K. X., Wang, L., He, Q., Jin, Z., Chen, W. Y., Sun, C. R., Pan, Y. J., 2020 Serine catabolism feeds NADH when respiration is impaired, Yang, L. F., Canaveras, J. C. G., Chen, Z. H., Wang, L., Jang, C., Morsher, R. J., Zhang, Z. Z., Ghergurovich, J. M., Su, X. Y., Mayr, J. A., Rabinowitz, J. D., 2020 Gas phase reaction between chromones and solvent in an electrospray ionization source, Liu, Z., Shao, Y. L., Wang, L., 2019 Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene, Benson, K. K., Hu, W., Weller, A. H., Chen, E. R., Khetarpal, S. A., Yoshino, S., Bone, W. P., Wang, L., Rabinowitz, J. D., Voight, B. F., Soccio, R. E., 2019 Metabolite exchange between mammalian organs quantified in pigs, Jang, C., Hui, S., Zeng, X., Cowan, A. J., Wang, L., Chen, L., Mrscher, R. J., Reyes, J., Frezza,C., Hwang, H. Y., Imai, A., Saito, Y., Okamoto, K., Vaspoli, C., Kasprenski, L., Zsido, G. A., Gorman, J. H., Gorman, R. C., Rabinowitz, J. D., 2019 Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics, Wang, L., Xing, X., Chen, L., Yang, L., Su, X., Rabitz, H. A., Lu, W., Rabinowitz, J. D., 2018 Extraction and quantitation of nicotinamide adenine dinucleotide redox cofactors, Lu, W., Wang, L., Chen, L., Hui, S., Rabinowitz, J. D., 2018 Pair of stereodynamic chiral benzylicaldehyde probes for determination of absolute configuration of amino acid residues in peptides by mass spectrometry, Wang, L., Zhe, J., Wang, X., Zeng, S., Sun, C., Pan, Y., 2017

Areas of Focus

Metabolomics and spatially resolved metabolic imaging
Targeted quantitative metabolomics and untargeted metabolic analysis
High-throughput multi-omics analysis based on population cohort biosamples

Publications

Gut bacterial nutrient preferences quantified in vivo, Zeng, X., Xing, X., Gupta, M., Keber, F. C., Lopez, J. G., Lee, Y. J., Roichman, A., Wang, L., Neinast, M. D., Donia, M. S., WÜhr, M., Jang, C., Rabinowitz, J. D., 2022
Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth, Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M., Lu, W., Davidson, S., Liang, G., Oh, T. G., Downes, M., Evans, R., Von Hoff, D., Guo, J. Y., Han, H., Rabinowitz, J. D., 2022
Spatially-resolved isotope tracing reveals tissue metabolic activity, Wang, L., Xing, X., Zeng, X. F., Jackson, S. R., TeSlaa, T., Wolff, J., Yang, L. F., McReynolds, M. R., Li, X., Rabinowitz, J. D., Davidson, S. M., 2022
Metabolite discovery through global annotation of untargeted metabolomics data, Chen, L., Lu, W., Wang, L., Xing, X., Chen, Z., Teng, X., Zeng, X., Muscarella, A. D., Shen, Y., Cowan, A., McReynolds, M. R., Kennedy, B. J., Lato, A. M., Campagna, S. R., Singh, M., Rabinowitz, J. D., 2021
Methionine synthase supports tumour tetrahydrogolate pools, Ghergurovich, J. M., Xu, X., Wang, J. Z., Yang, L., Ryseck, R., Wang, L., Rabinowitz, J. D., 2021
A genetic model of methionine restriction extends Drosophila health and lifespan, Parkhitko A. A., Wang, L., Filine, E., Jouandin, P., Leshchiner, D., Binari, R., Asara, J. M., Rabinowitz, J. D., Perrimon, N., 2021
The source of glycolytic intermediates in mammalian tissues, TeSlaa, T., Bartman, C. R., Jankowski, C., Zhang, Z., Xu, X., Xing, X., Wang, L., Lu, W., Hui, S., Rabinowitz, J. D., 2021
Metabolic excretion associated with nutrient growth dysregulation promotes the rapid evolution of an overt metabolic defect, Green, R., Wang, L., Hart, S. F. M., Lu, W., Shelding, D., Burton, J. C., Mi, H., Capel, A., Chen, H. A., Lin, A., Subramaniam, A. R., Rabinowitz, J. D., Shou, W., 2020
Quantitative fluxomics of circulating metabolites, Hui, S., Cowan, A. J., Zeng X., Yang, L., TeSlaa, T., Li, X., Bartman, C., Zhang, Z., Jang, C., Wang, L., Lu, W., Rojas, J., Baur, J., Rabinowitz, J. D., 2020
Sensitive bromine-labeled probe D-BPBr for simultaneous identification and quantification of chiral amino acids and amino containing metabolites profiling in human biofluid by HPLC/MS, Shen, K. X., Wang, L., He, Q., Jin, Z., Chen, W. Y., Sun, C. R., Pan, Y. J., 2020
Serine catabolism feeds NADH when respiration is impaired, Yang, L. F., Canaveras, J. C. G., Chen, Z. H., Wang, L., Jang, C., Morsher, R. J., Zhang, Z. Z., Ghergurovich, J. M., Su, X. Y., Mayr, J. A., Rabinowitz, J. D., 2020
Gas phase reaction between chromones and solvent in an electrospray ionization source, Liu, Z., Shao, Y. L., Wang, L., 2019
Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene, Benson, K. K., Hu, W., Weller, A. H., Chen, E. R., Khetarpal, S. A., Yoshino, S., Bone, W. P., Wang, L., Rabinowitz, J. D., Voight, B. F., Soccio, R. E., 2019
Metabolite exchange between mammalian organs quantified in pigs, Jang, C., Hui, S., Zeng, X., Cowan, A. J., Wang, L., Chen, L., Mrscher, R. J., Reyes, J., Frezza,C., Hwang, H. Y., Imai, A., Saito, Y., Okamoto, K., Vaspoli, C., Kasprenski, L., Zsido, G. A., Gorman, J. H., Gorman, R. C., Rabinowitz, J. D., 2019
Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics, Wang, L., Xing, X., Chen, L., Yang, L., Su, X., Rabitz, H. A., Lu, W., Rabinowitz, J. D., 2018
Extraction and quantitation of nicotinamide adenine dinucleotide redox cofactors, Lu, W., Wang, L., Chen, L., Hui, S., Rabinowitz, J. D., 2018
Pair of stereodynamic chiral benzylicaldehyde probes for determination of absolute configuration of amino acid residues in peptides by mass spectrometry, Wang, L., Zhe, J., Wang, X., Zeng, S., Sun, C., Pan, Y., 2017

Metabolomics Spatial Imaging Metabolic Flux Quantitative Analysis Mass Spectrometry Disease Metabolites Metabolic Targets Bioinformatics Multi-Omics Population Cohort

Dongyu Zhao - Peking University

Hua-Jun Wu - Peking University

Xianjiang Lan - Fudan University

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