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Lin Wang
Basic Medical Sciences
Peking Union Medical College
Beijing
Language: English, Chinese
Metabolomics
Spatial Imaging
Metabolic Flux
Quantitative Analysis
Mass Spectrometry
Disease Metabolites
Metabolic Targets
Bioinformatics
Multi-Omics
Population Cohort
Areas of Focus
- Metabolomics and spatially resolved metabolic imaging
- Targeted quantitative metabolomics and untargeted metabolic analysis
- High-throughput multi-omics analysis based on population cohort biosamples
Work Experience
- 2015-09 to 2017 - Beijing University of Technology - Research in single-cell mass spectrometry
- 2017 to 2021-11 - Princeton University - Postdoctoral Research
- 2021-11 to present - Chinese Academy of Medical Sciences & Peking Union Medical College - Researcher
Academic Background & Achievements
- 2015 - PhD in Science: Zhejiang University
- Selected for National Youth Talent Program
Publications
- Gut bacterial nutrient preferences quantified in vivo, Zeng, X., Xing, X., Gupta, M., Keber, F. C., Lopez, J. G., Lee, Y. J., Roichman, A., Wang, L., Neinast, M. D., Donia, M. S., WÜhr, M., Jang, C., Rabinowitz, J. D., 2022
- Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth, Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M., Lu, W., Davidson, S., Liang, G., Oh, T. G., Downes, M., Evans, R., Von Hoff, D., Guo, J. Y., Han, H., Rabinowitz, J. D., 2022
- Spatially-resolved isotope tracing reveals tissue metabolic activity, Wang, L., Xing, X., Zeng, X. F., Jackson, S. R., TeSlaa, T., Wolff, J., Yang, L. F., McReynolds, M. R., Li, X., Rabinowitz, J. D., Davidson, S. M., 2022
- Metabolite discovery through global annotation of untargeted metabolomics data, Chen, L., Lu, W., Wang, L., Xing, X., Chen, Z., Teng, X., Zeng, X., Muscarella, A. D., Shen, Y., Cowan, A., McReynolds, M. R., Kennedy, B. J., Lato, A. M., Campagna, S. R., Singh, M., Rabinowitz, J. D., 2021
- Methionine synthase supports tumour tetrahydrogolate pools, Ghergurovich, J. M., Xu, X., Wang, J. Z., Yang, L., Ryseck, R., Wang, L., Rabinowitz, J. D., 2021
- A genetic model of methionine restriction extends Drosophila health and lifespan, Parkhitko A. A., Wang, L., Filine, E., Jouandin, P., Leshchiner, D., Binari, R., Asara, J. M., Rabinowitz, J. D., Perrimon, N., 2021
- The source of glycolytic intermediates in mammalian tissues, TeSlaa, T., Bartman, C. R., Jankowski, C., Zhang, Z., Xu, X., Xing, X., Wang, L., Lu, W., Hui, S., Rabinowitz, J. D., 2021
- Metabolic excretion associated with nutrient growth dysregulation promotes the rapid evolution of an overt metabolic defect, Green, R., Wang, L., Hart, S. F. M., Lu, W., Shelding, D., Burton, J. C., Mi, H., Capel, A., Chen, H. A., Lin, A., Subramaniam, A. R., Rabinowitz, J. D., Shou, W., 2020
- Quantitative fluxomics of circulating metabolites, Hui, S., Cowan, A. J., Zeng X., Yang, L., TeSlaa, T., Li, X., Bartman, C., Zhang, Z., Jang, C., Wang, L., Lu, W., Rojas, J., Baur, J., Rabinowitz, J. D., 2020
- Sensitive bromine-labeled probe D-BPBr for simultaneous identification and quantification of chiral amino acids and amino containing metabolites profiling in human biofluid by HPLC/MS, Shen, K. X., Wang, L., He, Q., Jin, Z., Chen, W. Y., Sun, C. R., Pan, Y. J., 2020
- Serine catabolism feeds NADH when respiration is impaired, Yang, L. F., Canaveras, J. C. G., Chen, Z. H., Wang, L., Jang, C., Morsher, R. J., Zhang, Z. Z., Ghergurovich, J. M., Su, X. Y., Mayr, J. A., Rabinowitz, J. D., 2020
- Gas phase reaction between chromones and solvent in an electrospray ionization source, Liu, Z., Shao, Y. L., Wang, L., 2019
- Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene, Benson, K. K., Hu, W., Weller, A. H., Chen, E. R., Khetarpal, S. A., Yoshino, S., Bone, W. P., Wang, L., Rabinowitz, J. D., Voight, B. F., Soccio, R. E., 2019
- Metabolite exchange between mammalian organs quantified in pigs, Jang, C., Hui, S., Zeng, X., Cowan, A. J., Wang, L., Chen, L., Mrscher, R. J., Reyes, J., Frezza,C., Hwang, H. Y., Imai, A., Saito, Y., Okamoto, K., Vaspoli, C., Kasprenski, L., Zsido, G. A., Gorman, J. H., Gorman, R. C., Rabinowitz, J. D., 2019
- Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics, Wang, L., Xing, X., Chen, L., Yang, L., Su, X., Rabitz, H. A., Lu, W., Rabinowitz, J. D., 2018
- Extraction and quantitation of nicotinamide adenine dinucleotide redox cofactors, Lu, W., Wang, L., Chen, L., Hui, S., Rabinowitz, J. D., 2018
- Pair of stereodynamic chiral benzylicaldehyde probes for determination of absolute configuration of amino acid residues in peptides by mass spectrometry, Wang, L., Zhe, J., Wang, X., Zeng, S., Sun, C., Pan, Y., 2017
Awards
- Selected for National Youth Talent Program
