Professor | 王琳 | 数字化转型顾问

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Name	王琳
Contact Information	linwang@ibms.pumc.edu.cn
Language ability	英语, 中文
Province	北京

Upload Avatar (500 x 500)

Name

王琳

Contact Information

linwang@ibms.pumc.edu.cn

Language ability

英语, 中文

Province

北京

University/Lab Affiliation and Title	北京协和医学院
Faculty	Basic Medical Sciences
Academic Background & Achievements	2015 - 理学博士: 浙江大学入选国家级青年人才项目
Work Experience	2015-09 至 2017 - 北京工业大学 - 单细胞质谱分析研究 2017 至 2021-11 - 普林斯顿大学 - 博士后研究 2021-11 至今 - 中国医学科学院基础医学研究所&北京协和医学院 - 研究员
Awards	入选国家级青年人才项目

University/Lab Affiliation and Title

北京协和医学院

Faculty

Basic Medical Sciences

Academic Background & Achievements

2015 - 理学博士: 浙江大学
入选国家级青年人才项目

Work Experience

2015-09 至 2017 - 北京工业大学 - 单细胞质谱分析研究
2017 至 2021-11 - 普林斯顿大学 - 博士后研究
2021-11 至今 - 中国医学科学院基础医学研究所&北京协和医学院 - 研究员

Awards

入选国家级青年人才项目

Areas of Focus	代谢组学及空间分辨的代谢成像靶向定量代谢组学及非靶向代谢分析基于人群队列生物样本的高通量多组学分析
Publications	Gut bacterial nutrient preferences quantified in vivo, Zeng, X., Xing, X., Gupta, M., Keber, F. C., Lopez, J. G., Lee, Y. J., Roichman, A., Wang, L., Neinast, M. D., Donia, M. S., WÜhr, M., Jang, C., Rabinowitz, J. D., 2022 Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth, Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M., Lu, W., Davidson, S., Liang, G., Oh, T. G., Downes, M., Evans, R., Von Hoff, D., Guo, J. Y., Han, H., Rabinowitz, J. D., 2022 Spatially-resolved isotope tracing reveals tissue metabolic activity, Wang, L., Xing, X., Zeng, X. F., Jackson, S. R., TeSlaa, T., Wolff, J., Yang, L. F., McReynolds, M. R., Li, X., Rabinowitz, J. D., Davidson, S. M., 2022 Metabolite discovery through global annotation of untargeted metabolomics data, Chen, L., Lu, W., Wang, L., Xing, X., Chen, Z., Teng, X., Zeng, X., Muscarella, A. D., Shen, Y., Cowan, A., McReynolds, M. R., Kennedy, B. J., Lato, A. M., Campagna, S. R., Singh, M., Rabinowitz, J. D., 2021 Methionine synthase supports tumour tetrahydrogolate pools, Ghergurovich, J. M., Xu, X., Wang, J. Z., Yang, L., Ryseck, R., Wang, L., Rabinowitz, J. D., 2021 A genetic model of methionine restriction extends Drosophila health and lifespan, Parkhitko A. A., Wang, L., Filine, E., Jouandin, P., Leshchiner, D., Binari, R., Asara, J. M., Rabinowitz, J. D., Perrimon, N., 2021 The source of glycolytic intermediates in mammalian tissues, TeSlaa, T., Bartman, C. R., Jankowski, C., Zhang, Z., Xu, X., Xing, X., Wang, L., Lu, W., Hui, S., Rabinowitz, J. D., 2021 Metabolic excretion associated with nutrient growth dysregulation promotes the rapid evolution of an overt metabolic defect, Green, R., Wang, L., Hart, S. F. M., Lu, W., Shelding, D., Burton, J. C., Mi, H., Capel, A., Chen, H. A., Lin, A., Subramaniam, A. R., Rabinowitz, J. D., Shou, W., 2020 Quantitative fluxomics of circulating metabolites, Hui, S., Cowan, A. J., Zeng X., Yang, L., TeSlaa, T., Li, X., Bartman, C., Zhang, Z., Jang, C., Wang, L., Lu, W., Rojas, J., Baur, J., Rabinowitz, J. D., 2020 Sensitive bromine-labeled probe D-BPBr for simultaneous identification and quantification of chiral amino acids and amino containing metabolites profiling in human biofluid by HPLC/MS, Shen, K. X., Wang, L., He, Q., Jin, Z., Chen, W. Y., Sun, C. R., Pan, Y. J., 2020 Serine catabolism feeds NADH when respiration is impaired, Yang, L. F., Canaveras, J. C. G., Chen, Z. H., Wang, L., Jang, C., Morsher, R. J., Zhang, Z. Z., Ghergurovich, J. M., Su, X. Y., Mayr, J. A., Rabinowitz, J. D., 2020 Gas phase reaction between chromones and solvent in an electrospray ionization source, Liu, Z., Shao, Y. L., Wang, L., 2019 Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene, Benson, K. K., Hu, W., Weller, A. H., Chen, E. R., Khetarpal, S. A., Yoshino, S., Bone, W. P., Wang, L., Rabinowitz, J. D., Voight, B. F., Soccio, R. E., 2019 Metabolite exchange between mammalian organs quantified in pigs, Jang, C., Hui, S., Zeng, X., Cowan, A. J., Wang, L., Chen, L., Mrscher, R. J., Reyes, J., Frezza,C., Hwang, H. Y., Imai, A., Saito, Y., Okamoto, K., Vaspoli, C., Kasprenski, L., Zsido, G. A., Gorman, J. H., Gorman, R. C., Rabinowitz, J. D., 2019 Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics, Wang, L., Xing, X., Chen, L., Yang, L., Su, X., Rabitz, H. A., Lu, W., Rabinowitz, J. D., 2018 Extraction and quantitation of nicotinamide adenine dinucleotide redox cofactors, Lu, W., Wang, L., Chen, L., Hui, S., Rabinowitz, J. D., 2018 Pair of stereodynamic chiral benzylicaldehyde probes for determination of absolute configuration of amino acid residues in peptides by mass spectrometry, Wang, L., Zhe, J., Wang, X., Zeng, S., Sun, C., Pan, Y., 2017

Areas of Focus

代谢组学及空间分辨的代谢成像
靶向定量代谢组学及非靶向代谢分析
基于人群队列生物样本的高通量多组学分析

Publications

Gut bacterial nutrient preferences quantified in vivo, Zeng, X., Xing, X., Gupta, M., Keber, F. C., Lopez, J. G., Lee, Y. J., Roichman, A., Wang, L., Neinast, M. D., Donia, M. S., WÜhr, M., Jang, C., Rabinowitz, J. D., 2022
Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth, Yang, L., TeSlaa, T., Ng, S., Nofal, M., Wang, L., Lan, T., Zeng, X., Cowan, A., McBride, M., Lu, W., Davidson, S., Liang, G., Oh, T. G., Downes, M., Evans, R., Von Hoff, D., Guo, J. Y., Han, H., Rabinowitz, J. D., 2022
Spatially-resolved isotope tracing reveals tissue metabolic activity, Wang, L., Xing, X., Zeng, X. F., Jackson, S. R., TeSlaa, T., Wolff, J., Yang, L. F., McReynolds, M. R., Li, X., Rabinowitz, J. D., Davidson, S. M., 2022
Metabolite discovery through global annotation of untargeted metabolomics data, Chen, L., Lu, W., Wang, L., Xing, X., Chen, Z., Teng, X., Zeng, X., Muscarella, A. D., Shen, Y., Cowan, A., McReynolds, M. R., Kennedy, B. J., Lato, A. M., Campagna, S. R., Singh, M., Rabinowitz, J. D., 2021
Methionine synthase supports tumour tetrahydrogolate pools, Ghergurovich, J. M., Xu, X., Wang, J. Z., Yang, L., Ryseck, R., Wang, L., Rabinowitz, J. D., 2021
A genetic model of methionine restriction extends Drosophila health and lifespan, Parkhitko A. A., Wang, L., Filine, E., Jouandin, P., Leshchiner, D., Binari, R., Asara, J. M., Rabinowitz, J. D., Perrimon, N., 2021
The source of glycolytic intermediates in mammalian tissues, TeSlaa, T., Bartman, C. R., Jankowski, C., Zhang, Z., Xu, X., Xing, X., Wang, L., Lu, W., Hui, S., Rabinowitz, J. D., 2021
Metabolic excretion associated with nutrient growth dysregulation promotes the rapid evolution of an overt metabolic defect, Green, R., Wang, L., Hart, S. F. M., Lu, W., Shelding, D., Burton, J. C., Mi, H., Capel, A., Chen, H. A., Lin, A., Subramaniam, A. R., Rabinowitz, J. D., Shou, W., 2020
Quantitative fluxomics of circulating metabolites, Hui, S., Cowan, A. J., Zeng X., Yang, L., TeSlaa, T., Li, X., Bartman, C., Zhang, Z., Jang, C., Wang, L., Lu, W., Rojas, J., Baur, J., Rabinowitz, J. D., 2020
Sensitive bromine-labeled probe D-BPBr for simultaneous identification and quantification of chiral amino acids and amino containing metabolites profiling in human biofluid by HPLC/MS, Shen, K. X., Wang, L., He, Q., Jin, Z., Chen, W. Y., Sun, C. R., Pan, Y. J., 2020
Serine catabolism feeds NADH when respiration is impaired, Yang, L. F., Canaveras, J. C. G., Chen, Z. H., Wang, L., Jang, C., Morsher, R. J., Zhang, Z. Z., Ghergurovich, J. M., Su, X. Y., Mayr, J. A., Rabinowitz, J. D., 2020
Gas phase reaction between chromones and solvent in an electrospray ionization source, Liu, Z., Shao, Y. L., Wang, L., 2019
Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene, Benson, K. K., Hu, W., Weller, A. H., Chen, E. R., Khetarpal, S. A., Yoshino, S., Bone, W. P., Wang, L., Rabinowitz, J. D., Voight, B. F., Soccio, R. E., 2019
Metabolite exchange between mammalian organs quantified in pigs, Jang, C., Hui, S., Zeng, X., Cowan, A. J., Wang, L., Chen, L., Mrscher, R. J., Reyes, J., Frezza,C., Hwang, H. Y., Imai, A., Saito, Y., Okamoto, K., Vaspoli, C., Kasprenski, L., Zsido, G. A., Gorman, J. H., Gorman, R. C., Rabinowitz, J. D., 2019
Peak annotation and verification engine (PAVE) for untargeted LC-MS metabolomics, Wang, L., Xing, X., Chen, L., Yang, L., Su, X., Rabitz, H. A., Lu, W., Rabinowitz, J. D., 2018
Extraction and quantitation of nicotinamide adenine dinucleotide redox cofactors, Lu, W., Wang, L., Chen, L., Hui, S., Rabinowitz, J. D., 2018
Pair of stereodynamic chiral benzylicaldehyde probes for determination of absolute configuration of amino acid residues in peptides by mass spectrometry, Wang, L., Zhe, J., Wang, X., Zeng, S., Sun, C., Pan, Y., 2017

代谢组学空间成像代谢流定量分析质谱疾病代谢物代谢靶点生物信息学多组学人群队列

王光熙 - 北京大学

赵东宇 - 北京大学

吴华君 - 北京大学

Area of Focus
多组学 | 统计 | 数据分析 | 癌症 | 基因组学 | 生物信息学 | 计算生物学 | 研究 | 开发 | 应用

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